MansoorNSalehMD

Oncology • Birmingham, AL

Physician

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Office
2145 Bonner Way
Birmingham, AL 35243
Phone+1 205-978-0250

Fax+1 770-939-2887
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Education & Training

University of Alabama Medical CenterFellowship, Hematology and Medical Oncology, 1983 - 1985
Henry Ford HospitalResidency, Internal Medicine, 1980 - 1983
Ruprecht Karl University Faculty of MedicineClass of 1979

Certifications & Licensure

GA State Medical License 1994 - 2025
AL State Medical License 1983 - 2024
MI State Medical License 1982 - 2013
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2013

Clinical Trials

Liposomal Doxorubicin Plus Combination Chemotherapy in Treating Patients With AIDS-Associated Non-Hodgkin's Lymphoma Start of enrollment: 1997 Jun 01
Completed
Phase 1
ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer Start of enrollment: 1999 Jan 01
Terminated
Phase 2
Radioimmunotherapy in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma Start of enrollment: 1999 Nov 01
Completed
Phase 2
Open-label Study of CS-1008 for Subjects With Untreated and Unresectable Pancreatic Cancer Start of enrollment: 2007 Aug 15
Completed
Phase 2
Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65 Start of enrollment: 2010 Oct 01
Active, not recruiting
Phase 3
Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung Cancer Start of enrollment: 2011 Jan 11
Terminated
Phase 3
Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting Start of enrollment: 2010 Dec 02
Completed
Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer Start of enrollment: 2011 Apr 07
Completed
Phase 2
Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer Start of enrollment: 2011 Sep 30
Terminated
Phase 1, Phase 2
A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer Start of enrollment: 2012 Oct 01
Completed
Phase 1, Phase 2
A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL) Start of enrollment: 2012 Oct 31
Completed
Phase 2
A Phase 1 Study of MM-141 in Patients With Advanced Solid Tumors Start of enrollment: 2012 Nov 01
Completed
Phase 1
A Study That Switched Patients From Imatinib to Nilotinib and Then Was Followed by Treatment Cessation Start of enrollment: 2013 Aug 12
Completed
Phase 2
Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies Start of enrollment: 2013 Mar 14
Terminated
Phase 2
Study of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast Cancer.(MONALEESA-2) Start of enrollment: 2013 Dec 17
Completed
Phase 3
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 2
Phase 2 Trial of Carfilzomib for Metastatic Castration-resistant Prostate Cancer Following Treatment Start of enrollment: 2014 Apr 01
Completed
Phase 2
A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma Start of enrollment: 2015 Jan 01
Completed
Phase 1, Phase 2
A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents Start of enrollment: 2016 Oct 21
Completed
Phase 1
An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies Start of enrollment: 2017 May 25
Terminated
Phase 1
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Publications & Presentations

PubMed

4 citations
A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer.
Ernest Nadal, Mansoor Saleh, Santiago Ponce Aix, Maria Ochoa-de-Olza, Sandip Pravin Patel, Scott Antonia, Yumin Zhao, Ivelina Gueorguieva, Michael Man, Shawn T Estrem,...> ;BMC Cancer. 2023 Jul 28
5 citations
A signature ofanddepletion, and a link with bacterial glutamate degradation in the Kenyan colorectal cancer patients.
Sarah Obuya, Amr Elkholy, Nagavardhini Avuthu, Michael Behring, Prachi Bajpai, Sumit Agarwal, Hyung-Gyoon Kim, Nefertiti El-Nikhely, Pamela Akinyi, James Orwa, Farrukh...> ;Journal of Gastrointestinal Oncology. 2022 Oct 1
10 citations
Artificial intelligence and machine learning for early detection and diagnosis of colorectal cancer in sub-Saharan Africa.
Akbar K Waljee, Eileen M Weinheimer-Haus, Amina Abubakar, Anthony K Ngugi, Geoffrey H Siwo, Gifty Kwakye, Amit G Singal, Arvind Rao, Sameer D Saini, Andrew J Read, Jes...> ;Gut. 2022 Jul 1
84 citations
FIGHT-101, a first-in-human study of potent and selective FGFR 1-3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies.
V Subbiah, N O Iannotti, M Gutierrez, D C Smith, L Féliz, C F Lihou, C Tian, I M Silverman, T Ji, M Saleh> ;Annals of Oncology. 2022 May 1
23 citations
Targeting CD38 and PD-1 with isatuximab plus cemiplimab in patients with advanced solid malignancies: results from a phase I/II open-label, multicenter study.
Paolo Andrea Zucali, Chia-Chi Lin, Bradley C Carthon, Todd M Bauer, Marcello Tucci, Antoine Italiano, Roberto Iacovelli, Wu-Chou Su, Christophe Massard, Mansoor Saleh,...> ;Journal for Immunotherapy of Cancer. 2022 Jan 1
Treatment of immune thrombocytopenia with eltrombopag in patients who had and who had not received prior rituximab: post-hoc analysis of the EXTEND study.
Oliver Meyer, Raymond S.M. Wong, Abderrahim Khelif, Miona Stankovic, Joan Maier, Mansoor N. Saleh, James B. Bussel> ;British Journal of Haematology. 2021 Aug 30
45 citations
Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-Type TP53.
Mansoor N. Saleh, Manish R. Patel, Todd M. Bauer, Sanjay Goel, Gerald Steven Falchook, Geoffrey I. Shapiro, Ki Y. Chung, Jeffrey R. Infante, Robert M. Conry, Guilherme...> ;Clinical Cancer Research. 2021 Oct 1
10 citations
Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women.
Mansoor N. Saleh, Darshan S. Chandrashekar, Sayed Shahin, Sumit Agarwal, Hyung-Gyoon Kim, Michael Behring, Asim Jamal Shaikh, Zahir Moloo, Isam-Eldin Eltoum, Clayton Y...> ;Translational Oncology. 2021 Apr 8
7 citations
Association of premature atherosclerotic cardiovascular disease with higher risk of cancer: a behavioral risk factor surveillance system study.
Vardhmaan Jain, Mahmoud Al Rifai, Daria Brinzevich, Mehrunnissa Taj, Mansoor N. Saleh, Chayakrit Krittanawong, Jaideep Patel, Ashley Patel, Michelle T. Lee, Dhruv Maht...> ;European Journal of Preventive Cardiology. 2021 May 31
7 citations
Breast cancer risk factors in relation to molecular subtypes in breast cancer patients from Kenya.
Shahin Sayed, Shaoqi Fan, Zahir Moloo, Ronald Wasike, Peter Bird, Mansoor N. Saleh, Asim Jamal Shaikh, Jonine D. Figueroa, Richard Naidoo, Francis Makokha, Kevin Gardn...> ;Breast Cancer Research. 2021 Mar 3
3 citations
Phase I Study of Ramucirumab Plus Merestinib in Previously Treated Metastatic Colorectal Cancer: Safety, Preliminary Efficacy, and Pharmacokinetic Findings
Mansoor N. Saleh, Philippe A. Cassier, Lauriane Eberst, Gurudatta Naik, Van K. Morris, Shubham Pant, C. Terret, Ling Gao, Amanda Long, Huzhang Mao, Samuel McNeely, Eri...> ;The Oncologist. 2020 Nov 1
3 citations
Clinical Investigator Training Program (CITP) - A practical and pragmatic approach to conveying clinical investigator competencies and training to busy clinicians.
Mansoor N. Saleh, Gurudatta Naik, Penelope Jester, Cynthia I. Joiner, Elizabeth Westfall, David W. Kimberlin, James H. Willig, David T. Redden, Juliette Southworth, Ma...> ;Contemporary Clinical Trials Communications. 2020 Jun 12
33 citations
First-In-Human Phase 1 Clinical Trials - A Single-Center Experience In The Era Of Modern Oncotherapeutics
Ravi Kumar Paluri, Peng Li, Ashley M. Anderson, Lakshminarayana Nandagopal, Traci McArdle, Matthew D. Young, Franscisco Robert, Gurudatta Naik, Mansoor N. Saleh> ;Scientific Reports. 2020 May 13
8 citations
TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormon...
Christos Vaklavas, Brian S. Roberts, Katherine E. Varley, Nan Lin, Minetta C. Liu, Hope S. Rugo, Shannon Puhalla, Rita Nanda, Anna Maria Storniolo, Lisa A. Carey, Mans...> ;Breast Cancer Research. 2020 Feb 18
21 citations
Breast Cancer knowledge, perceptions and practices in a rural Community in Coastal Kenya
Shahin Sayed, Anthony K. Ngugi, Megan Mahoney, Jaameeta Kurji, Zohray Talib, Sarah B. Macfarlane, Theresa A. Wynn, Mansoor N. Saleh, Amyn Lakhani, Esther Nderitu, Feli...> ;BMC Public Health. 2019 Feb 12
19 citations
Changes in health-related quality of life with long-term eltrombopag treatment in adults with persistent/chronic immune thrombocytopenia: Findings from the EXTEND study.
Abderrahim Khelif, Mansoor N. Saleh, Abdulgabar Salama, Maria Socorro O Portella, Mei Sheng Duh, Jasmina I. Ivanova, Kelly M. Grotzinger, Anuja Roy, James B. Bussel> ;American Journal of Hematology. 2019 Feb 1
7 citations
Phase 1b trial of nintedanib in combination with bevacizumab in patients with advanced solid tumors
Ravi Kumar Paluri, Ankit Madan, Peng Li, Benjamin P Jones, Mansoor N. Saleh, Mary Jerome, Deborah Miley, Jennifer Keef, Francisco Robert> ;Cancer Chemotherapy and Pharmacology. 2019 Jan 2
60 citations
Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models
Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua M. Dempster, Mark A. Murakami, Kay Shigemori, Sara N. Morrow, Alexandria V...> ;Nature Communications. 2018 May 22
4 citations
So You Want to Be a Principal Investigator.
Mansoor N. Saleh, Gurudatta Naik> ;Journal of Oncology Practice. 2018 May 11
3 citations
Promoting clinical breast evaluations in a lower middle-income country setting: An approach toward achieving a sustainable breast health program
Roziya Buribekova, Irina Shukurbekova, Surayo Ilnazarova, Nekruz Jamshevov, Guldarbogh Sadonshoeva, Saleem Sayani, Aliya Aminmuhammad, Farin Amersi, Sheemain Asaria, M...> ;Journal of Global Oncology. 2018 Jan 25
8 citations
Ethnicity and breast cancer characteristics in Kenya.
Shahin Sayed, Zahir Moloo, Ronald Wasike, Peter Bird, Raymond Oigara, Faith Wambui Njoroge, Asim Jamal Shaikh, Satya Prasad, Sudhir Vinayak, Gretchen L. Gierach, Sanfo...> ;Breast Cancer Research and Treatment. 2018 Jan 1
61 citations
Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide.
Dana E. Rathkopf, Matthew R. Smith, Charles J. Ryan, William R. Berry, N.D. Shore, Glenn Liu, Celestia S. Higano, Joshi J. Alumkal, Ralph J. Hauke, Ronald F. Tutrone, ...> ;Annals of Oncology. 2017 Sep 1
194 citations
Safety and efficacy of long-term treatment of chronic/persistent ITP with eltrombopag: final results of the EXTEND study
Raymond S.M. Wong, Mansoor N. Saleh, Abderrahim Khelif, Abdulgabar Salama, Maria Socorro O Portella, Paul Burgess, James B. Bussel> ;Blood. 2017 Dec 7
1 citations
Academic Cancer Center Phase I Program Development
Arthur E. Frankel, Keith T. Flaherty, George J. Weiner, Robert T. Chen, Nilofer S. Azad, Michael J. Pishvaian, John A. Thompson, Matthew H. Taylor, Daruka Mahadevan, A...> ;The Oncologist. 2017 Apr 1
62 citations
Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone
Dana E. Rathkopf, Emmanuel S. Antonarakis, Neal D. Shore, Ronald F. Tutrone, Joshi J. Alumkal, Charles J. Ryan, Mansoor N. Saleh, Ralph J. Hauke, Rajesh Bandekar, Edna...> ;Clinical Cancer Research. 2017 Jul 15
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Press Mentions

Aga Khan University Hospital Launches Cancer Clinical Trials UnitNovember 6th, 2020
First Human Trials of Drug to Prevent Death Due to Severe Blood LossOctober 21st, 2015