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Marc Halterman, MD, Neurology, Buffalo, NY

MarcHaltermanMDPhD, FAHA

Neurology • Buffalo, NY

Professor of Neurology, Senior Associate Dean for Research

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Summary

  • Dr. Halterman is professor of neurology and the senior associate dean for research at the Jacobs School of Medicine and Biomedical Sciences. He received his B.S. in Chemistry from Georgetown University and M.D., Ph.D. from the University of Rochester. After completing his residency at the University of Rochester, he joined the Department of Neurology faculty in 2006. From 2020-2023, Dr. Halterman served as Chair of Neurology at Stony Brook University and Co-Director of the Stony Brook Neurosciences Institute. Work in the Halterman Lab focuses on defining novel therapies for acute stroke and cardiac arrest, neural-immune interactions, and basic mechanisms of reperfusion injury. These studies have received support from the NIH, DoD, and AHA. Dr. Halterman holds patents in the areas of gene transfer and drug discovery.

Education & Training

  • University of Rochester
    University of RochesterResidency, Neurology, 2003 - 2006
  • University of Rochester
    University of RochesterInternship, Internal Medicine, 2002 - 2003
  • University of Rochester School of Medicine and Dentistry
    University of Rochester School of Medicine and DentistryClass of 2002, MD, Distinction in Research
  • University of Rochester
    University of RochesterPh.D., Microbiology & Immunology, 2002
  • Georgetown University
    Georgetown UniversityB.S., Chemistry, 1992

Certifications & Licensure

  • NY State Medical License
    NY State Medical License 2005 - 2024
  • American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

  • Nominee, Landis Award for Outstanding Mentorship NINDS, 2018
  • Alpha Omega Alpha Medical Honor Society University of Rochester, 2002
  • Gilbert B. Forbes Prize in Pediatric Research University of Rochester, 1994
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Publications & Presentations

PubMed

Journal Articles

  • Chopper is pro death regardless of the effect of p75ICD on sensitivity to oxidative stress  
    Qazi A, Halterman MW, Mi Z., Zhang T. and NF Schor, Oxid Med Cell Longev, 1/1/2011
  • The Paradoxof the Neutrophil?s Role in Tissue Injury: A review  
    SegelGB, HaltermanMWand MA Lichtman, J Leukocyte Biol, 1/1/2010
  • In-tube protocol modification improves transfection rates in murine neuronal cultures  
    Halterman MW, Giuliano R, Schor NF, J Neurosci Meth, 1/1/2009
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Books/Book Chapters

  • Handbook of Experimental Pharmacology: CNS Neuroprotection 
    Chapter: Developing gene-based neuroprotection strategies using herpes amplicon vectors. 
    Halterman MW and HJ FederoffEditors: FW Marcoux and DW Choi.Springer-Verlag, New York, NY2002
  • The Synapse in Development, Health and Disease 
    Chapter: Molecular Modification of neural networks: altering synaptic function through the use of viral mediated gene transfer. 
    Halterman MW and Federoff HJEditors: B.W. Festoff.JAI Press, Greenwich, CT1997

Abstracts/Posters

  • Chronic brain dysfunction driven by acute systemic inflammation. Keystone Symposia on neuroinflammation:
    Trzeciak A, Lerman Y, Mai N, Halterman M, and Kim M, Concepts, Characteristics, Consequences, Keystone, CO, 1/19/2017
  • Lung redox state modulates neutrophil priming during systemic inflammation.
    Gates K, Mai N, Prifti L, and Halterman MW, Keystone Symposia on Neuroinflammation: Concepts, Characteristics, Consequences, Keystone, CO, 1/19/2017
  • 9-tert butyl doxycycline inhibits neuronal injury and neutrophil trafficking after global ischemia.
    Mai N, Prifti L, Halterman MW, International Stroke Conference, Los Angeles, CA, 1/1/2016
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Lectures

  • Targeting immune-mediated cerebral reperfusion injury in the post cardiac arrest syndrome (PCAS) 
    University of Massachusetts, Worchester, MA, 2017; University of Pittsburgh, Pittsburgh, PA, 2017; N - 1/15/2018
  • Priming effects of endotoxemia on neutrophil activation, neuroinflammation and reperfusion injury following transient global ischemia 
    Clearwater Beach, FL - 1/30/2017
  •  
    Hamilton College, Clinton, NY - 1/2/2017
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Press Mentions

  • AHA Grants Will Accelerate Search for New Stroke Therapies
    AHA Grants Will Accelerate Search for New Stroke TherapiesJune 27th, 2018

Grant Support

  • Defining Neurotherapeutic Targets In Hypoxia-Induced CHOP-10 Signaling NetworksNational Institute Of Neurological Disorders And Stroke2010–2012
  • Targeting Phosphatase Regulated Cleavage Of Hif-1-Alpha In Ischemic Brain InjuryNational Institute Of Neurological Disorders And Stroke2011
  • Defining Neurotherapeutic Targets In Hypoxia-Induced CHOP-10 Signaling NetworksNational Institute Of Neurological Disorders And Stroke2008–2009
  • Sensing Hypoxia In The CNS Using Herpes VectorsNational Institute Of Mental Health1998–2002

External Links

  • Rochester Profilehttps://www.urmc.rochester.edu/people/20663216-marc-w-halterman
  • Lab Websitehttps://www.urmc.rochester.edu/labs/neurovascular-protection-group.aspx

Dr. Marc Halterman, Dr. Marc Halterman, MD, Dr. M Halterman