Marc Pelletier MD MSc, FRCSC

Adult Cardiac Surgery, Cardiopulmonary Transplantation, Minimally Invasive Cardiac Surgery, Minimally Invasive Thoracic Surgery

Chief, Division of Cardiac Surgery Yale School of Medicine, Yale University Surgeon-in-chief, Heart and Vascular Center, Yale New Haven Hospital

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330 Cedar St Ste 204New Haven, CT 06510
Phone+1 203-785-5000
Fax+1 216-844-1202

Summary

Dr. Marc Pelletier is the Chief of Cardiac Surgery at Yale
School of Medicine and Physician-in-Chief of Cardiac
Surgery for the Heart and Vascular Center of Yale New
Haven Health System. Dr. Pelletier joined Yale from
University Hospitals where he served as Division Chief
in Cardiac Surgery and held the Jay L. Ankeney
Professorship in Cardiothoracic Surgery at Case
Western Reserve University in Cleveland, Ohio. Prior
to that, he served as surgical director of the TAVR
program in the Division of Cardiac Surgery at Brigham
and Women's Hospital and Harvard Medical School.
He joined the Brigham group in 2016 after 9 years as
Head of Cardiac Surgery at the New Brunswick Heart
Centre, which followed a period as Assistant Professor
at Stanford University. Dr. Pelletier trained at McGill University in cardiac surgery and Stanford
University in cardiothoracic transplantation and ventricular assist devices. His areas of specialty include
TAVR procedures, minimally invasive valve surgery, aortic valve and aortic root surgery, surgery for
heart failure and minimally invasive coronary bypass surgery. He has authored over 130 peer-reviewed
publications, with over 130 abstracts accepted at scientific meetings and over 120 invited and local talks.
Dr. Pelletier is currently the Program Chair of the STS 2026 meeting and serves on multiple workforces
for the STS including the Council on Education and the Cardiac and Vascular Surgery workforce. He was
chair of the Royal College of Surgeons of Canada’s examination board in cardiac surgery from 2014-2018
and in 2018 received the Larry Cohn Outstanding Teacher Award for surgical education. In 2025, he was
awarded the Socrates Award by the Thoracic Surgery Residents Association recognizing an outstanding
senior cardiothoracic surgery faculty member in North America for their commitment to resident
education and mentorship. In 2021 he was awarded the Distinguished Surgeon designation at
UH and was named Cleveland Top Doc 2021,22,23,24.

Yale Medicine Cardiothoracic Surgeon Marc Pelletier, MD

Dr. Pelletier, chief of cardiac surgery at Yale, shares his thoughts on innovation and exciting procedures in cardiac surgery.

Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Thoracic Surgery, 2000 - 2001
McGill UniversityResidency, 1994 - 2000
McGill UniversityM.Sc., 2000
Dalhousie University Faculty of MedicineClass of 1994
Mount Allison UniversityB.Sc., Chemistry (Honors), 1990

Certifications & Licensure

OH State Medical License 2019 - 2026
CA State Medical License 2000 - 2025
CT State Medical License 2024 - 2025
MA State Medical License 2016 - 2021

Awards, Honors, & Recognition

Dr. Larry Cohn Outstanding Teacher Award Brigham and Women's Hospital, 2018
Supervising author, Andrew Foster Young Investigator Award Society of Thoracic Surgeons, 2017
Specialist of the Year Royal College of Physicians and Surgeons of Canada, 2014
Finalist-C. Walton Lellehei Resident Forum 2003
Best paper published in the Annals RCPSC Royal College of Physicians and Surgeons of Canada, 2001
MacLean-Mueller Prize Canadian Journal of Surgery, 2000
Co-author, 8th Annual TSDA Award Thoracic Surgery Directors Association, 1999
Lead-author, 7th Annual TSDA Award Thoracic Surgery Directors Association, 1998
Edward Charette Research Prize McGill University, 1997
First Prize, Lederle Essay Contest Dalhousie University, 1993
First Class Honors Mount Allison University, 1990
Rhodes Scholarship Candidate Mount Allison University, 1990
Golden "A" Award Recipient Mount Allison University, 1990
Rev. C. N. Brown Scholarship Mount Allison University, 1989
Junior of the Year Award Mount Allison University, 1988
Dr. L. A. Goodridge Scholarship Recipient Mount Allison University, 1986
Dean's List Mount Allison University, 1986
Noranda Scholarship Recipient Mount Allison University, 1986
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Clinical Trials

MitraClip REPAIR MR Study Start of enrollment: 2020 Jul 21
ACTIVE_NOT_RECRUITING
NA

Publications & Presentations

PubMed

Comparison of post-operative inflammatory biomarkers between minimal invasive extracorporeal circulation and conventional extracorporeal circulation in cardiac surgery...
Karam R Motawea, Momen Ibrahim, Amro Essam Amer, Omneya Kandil, Youmna Abourady
Perfusion. 2025-10-08
Long-Term Impact Of Permanent Pacing After Mitral Valve Surgery: A Scoping Review Of Current Literature.
Adham H. El Sherbini, Hasheminia Amin, Nazanin Soghrati, Aparna Kuchibhatla, Salah Elsherif
Portuguese Journal of Cardiac Thoracic and Vascular Surgery. 2025-08-31
Defining the Learning Curve in Minimally Invasive Cardiac Surgery: A Systematic Review and Meta-Analysis.
Abdelrahman Elsebaie, Christina S Boutros, Ahmed K Awad, Mohammed Sanad, Marc Pelletier
The Annals of Thoracic Surgery. 2025-08-29

Journal Articles

Images in Intervention Transcatheter Aortic Valve Replacement for Bioprosthetic Aortic Stenosis in Pregnancy
Pinak Shah, Tsuyoshi Kaneko, Natalia Berry, Katherine Economy, Douglas Shook, Piotr Sobieszczyk, Charles Nyman, Michael N Singh, Marc Pelletier, ScienceDirect

Abstracts/Posters

Endoscopic vein harvest is associated with lower rates of leg wound infection at 30 days following cardiac surgery.
Hassan A, Yip AM, MacLeod JB, Lutchmedial S, Ouzounian M, Brown CD, Forgie R, Pelletier MP, Can J Cardiol, Canadian Cardiovascular Congress, Montreal QC, 1/17/2013
Increasing volume of packed red blood cell transfusion is associated with in-hospital adverse events following cardiac surgery.
Hassan A, MacLeod JB, Yip AM, Ouzounian M, Lutchmedial S, O'Reilly B, Brown C, Forgie R, Pelletier MP, Can J Cardiol, Canadian Cardiovascular Congress, Toronto, ON, 1/27/2012
Long-term results following mitral valve repair surgery performed at a small-volume cardiac surgery center between 1991 and 2008.
Forgie R, Dube C, Roy L, Yip AM, Pelletier MP, Brown C, Parrott J, Hassan A, Can J Cardiol, Canadian Cardiovascular Congress, Toronto, ON, 1/27/2012
The effect of brand of heparin on peri-operative transfusion rates in patients undergoing cardiac surgery.
Hassan A, Kang N, Yip AM, Justason S, Ouzounian M, Lutchmedial S, O'Reilly B, Pelletier MP, Can J Cardiol, Canadian Cardiovascular Congress, Toronto, ON, 1/27/2012
"Factor VIII Inhibitor Bypassing Activity (FEIBA) as an Adjunct in Post-Cardiotomy Bleeding."
Pelletier MP, Rioux M, Hassan A, Forgie R, Brown C, Canadian Cardiovascular Congress 2011, Vancouver, British Columbia, Canada, 1/24/2011
"Novel Application of the Impella Device."
Bewick D, Pelletier M, Hassan A, Canadian Cardiovascular Congress 2011, Vancouver, British Columbia, Canada, 1/23/2011
The Impact of Wait Times on Rates of Adverse In-Hospital and 30-Day Outcomes Among Elective Patients Undergoing Coronary Artery Bypass Grafting.
Hassan A, Yip AM, Doucet J, Pelletier MP, Canadian Journal of Cardiology, Montreal, PQ, 1/23/2010
Telehealth Home Monitoring Unit for Cardiac Surgery Patients: Impact on 30-Day Outcomes.
Hassan A, Yip AM, Pelletier MP, Brown C, Forgie R, Parrot J, Palmer K, Canadian Journal of Cardiology, Montreal, PQ, 1/23/2010
Peripheral upregulation of the apelin-APJ signaling pathway as an early response to ischemic heart failure.
Sheikh AY, Chun HJ, Kutschka I, Ardigo D, Hendry SL, Goyt G, Caffarelli AD, Pelletier MP, Quertermous T, Robbins RC, Society of Thoracic Surgeons, Chicago, IL, 1/31/2006
Myocardial ischemia-reperfusion injury limits early survival of transplanted bone marrow stem cells.
Sheikh AY, Cao F, Ardigo D, Hendry SL, Kraft DL, Pearl J, Wang Q, Contag C, Pelletier MP, Weissman IL, Wu JC, Robbins RC, Society of Thoracic Surgeons, Chicago, IL, 1/30/2006
Mechanisms to improve MSC delivery and retainment in ischemic myocardium.
Schrepfer S, Deuse T, Reichenspurner H, Robbins RC, Pelletier MP, AHA Young Investigator Forum, San Francisco, CA, 1/29/2006
Update on pediatric mechanical ventricular assist devices.
Pelletier MP, 32nd Annual Meeting, Western Thoracic Surgical Association, Sun Valley, ID, 1/23/2006
Development of a novel platform device for reliable and reproducible rodent echocardiography.
Sheikh AH, Kutschka I, Sista R, Hendry SL, Chun HJ, Hoyt G, Pelletier MP, Quertermous T, Wu JC, Robbins RC, 1st Annual Academic Surgical Congress, San Diego, CA, 1/7/2006
Tissue engineered, bilayered living skin substitute (Apligraf®) prevents contraction in acute excisional wounds.
Sheikh AH, Rollins MD, Hendry SL, Pearl JI, Pelletier MP, Robbins RC, Hopf HW, Hunt TK, 1st Annual Academic Surgical Congress, San Diego, CA, 1/7/2006
Murine model of ischemia reperfusion for myocardial restoration with cellular transplantation.
Hendry SL, Sheikh AY, Schrepfer S, Pelletier M, Wu JC, Yang PC, Robbins RC, 3rd Annual Symposium of the American Heart Association Council on Basic Cardiovascular Sciences - Translation of Basic Insights into Clinical Practice, Keystone, CO, 1/1/2006
Myocardial restoration with embryonic stem cell transplantation in a murine myocardial infarction model.
Hendry SL, Arai T, Dylla SJ, Drukker M, Sheikh AY, Kutschka I, Hoyt G, Connolly A, Pelletier M, Wu JC, Yang PC, Robbins RC, American Heart Association, Dallas, TX, 1/12/2005
Improving the Quality of Coronary Bypass Surgery with Intraoperative Angiography: Validation of a New Technique.
Desai ND, Miwa S, David Kodama, Gideon Cohen, George T. Christakis, Bernard S. Goldman, Mark O. Baerlocher, Marc P. Pelletier, Stephen E. Fremes, American College of Cardiology, 1/1/2005
Eleven year follow-up of the St. Jude Toronto Stentless Porcine Valve.
Desai ND, Merin O, Herman J, Cohen GN, Pelletier MP, Fremes SE, Goldman BS, Christakis GT, Mobilos S, Sever J, 40th Annual Meeting of the Society of Thoracic Surgeons, San Antonio, TX, 1/27/2004
Platelet transfusions are a potential cause of mortality and morbidity after coronary artery bypass grafting.
Desai ND, Kapila V, Pelletier MP, Cohen GC, Goldman BS, Christakis GT, Fremes SE, Canadian Cardiovascular Congress, Calgary, AB, 1/25/2004
Comprehensive coronary bypass graft assessment using the Novadaq SpyTM intraoperative angiography system: Innovation towards perfect graft patency.
Desai ND, Miwa S, Baerlocher M, Kapila V, Pelletier MP, Goldman BS, Cohen GC, Christakis GT, Fremes SE, Canadian Cardiovascular Congress, Calgary, AB, 1/25/2004
Improved heart transplant survival in patients bridged with ventricular assist device.
Chan MCY, Moffatt S, Shao ES, Cantin B, Pelletier M, Oyer P, Robbins RC, Hunt SA, J Heart Lung Transp, 24th Annual Meeting of the International Society for Heart and Lung Transplantation, San Francisco, CA, 1/21/2004
Why is off-pump coronary surgery uncommon in Canada? A population-based survey of Canadian cardiac surgeons.
Desai ND, Pelletier MP, Goldman BS, Fremes SE, Can J Card, Canadian Cardiovascular Congress, Toronto, Ontario, 1/28/2003
Establishing the safety of coronary artery bypass grafting in elderly patients.
Merin O, Desai ND, Goldman BS, Christakis GT, Cohen GN, Fremes SE, Pelletier MP, Can J Card, Canadian Cardiovascular Congress, Toronto, Ontario, 1/28/2003
Is multiple arterial grafting safe in urgent coronary bypass surgery?
Desai ND, Pelletier MP, Cohen G, Goldman BS, Christakis GT, Fremes SE, Can J Card, Canadian Cardiovascular Congress, Toronto, Ontario, 1/28/2003
Indocyanine green - Laser coronary angiography: A novel method of intraoperative patency assessment.
Desai ND, Pelletier MP, Cohen G, Mallidi HR, Christakis GT, Goldman BS, Fremes SE, Can J Card, Canadian Cardiovascular Congress, Toronto, Ontario, 1/28/2003
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Lectures

Isolated Aortic Stenosis With Very Small Annulus: TAVR Vs Root Enlargement
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
"The Perceval sutureless valve: A comprehensive review."
Boston, MA - 1/1/2017
"Advances in cardiac surgery"
Boston, MA - 1/1/2016
"Evolving options for aortic valve replacement"
Brigham and Women's Hospital, Boston, MA - 1/1/2016
"Areas of evolution in cardiac surgery: TAVR and sutureless valves, MIS options, and role of factor eight inhibitor bypassing activity (FEIBA) in refractory coagulopat...
Shapiro Cardiovascular Center, Boston, MA - 1/1/2016
"The TAVI procedure using balloon expandable valves"
Montreal, QC, Canada - 1/1/2015
"Coronary artery bypass grafting is best therapy for left main stenosis"
Mont Tremblant, Quebec, Canada - 1/1/2015
"Cannulation of left ventricular apex for cardiopulmonary bypass during TAVI"
Montreal, PQ, Canada - 1/1/2014
"Minimally invasive aortic valve replacement"
Mont Tremblant, PQ, Canada - 1/1/2014
"Emergency room thoracotomy"
Dieppe, NB, Canada - 1/1/2014
"Aortic Stenosis: What are the therapeutic options?"
Saint John, NB, Canada - 1/1/2014
"Transcatheter Aortic Valve Implantation (TAVI): Challenges and Opportunities"
Saint John, NB, Canada - 1/1/2013
"Cardiovascular Surgery - Current Practice and New Innovations"
Saint John, NB, Canada - 1/1/2013
LVADs as "Destination Therapy" in refractory CHF.
Saint John, NB, Canada - 1/1/2012
"Identifying the high-risk patient with severe aortic stenosis: A growing epidemic - A surgeon's perspective"
Saint John, NB, Canada - 1/1/2012
AVI Debate. Con: TAVI is now the new standard of care for aortic stenosis.
Toronto, ON, Canada - 1/1/2012
Emerging technologies in cardiac surgery at the NBHC
Saint John, NB, Canada - 1/1/2011
The New Brunswick Heart Centre percutaneous valve program - "Exciting Times."
St. John, NB, Canada - 1/1/2011
Transcatheter valve program at the New Brunswick Heart Centre
St. John, NB, Canada - 1/1/2010
Cardiac surgery update at the NBHC
Moncton, NB, Canada - 1/1/2010
"Cardiac disease in women"
Fredericton, NB, Canada - 1/1/2009
2009 Cardiac Surgery Statistics
Saint John, NB, Canada - 1/1/2009
"Challenges of introducing new technology in cardiac surgery: US vs Canadian experience."
Halifax, NS, Canada - 1/1/2009
"What's new in cardiac surgery?"
Saint John, NB, Canada - 1/1/2009
Role of FEIBA in cardiac surgery.
Saint John, NB, Canada - 1/1/2009
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