MargaretRGyetkoMD

Pulmonology • Ann Arbor, MI

Critical Care Medicine

Professor of Medicine, Senior Associate Dean for Faculty and Faculty Development University of Michigan

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Office
1500 East Medical Center Dr
3rd Floor Taubman Ctr Recp C
Ann Arbor, MI 48109
Phone+1 734-647-9342

Fax+1 734-615-5348
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Education & Training

University of Michigan Health SystemFellowship, Pulmonary Disease and Critical Care Medicine, 1985 - 1988
University of Michigan Health SystemResidency, Internal Medicine, 1981 - 1985
Michigan State University College of Human MedicineClass of 1981

Certifications & Licensure

MI State Medical License 1982 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Publications & Presentations

PubMed

12 citations
Symptom-related sputum microbiota in stable chronic obstructive pulmonary disease.
Wenqi Diao, Ning Shen, Yipeng Du, John R. Erb-Downward, Xiaoyan Sun, Chenxia Guo, Qian Ke, Gary B. Huffnagle, Margaret R. Gyetko, Bei He> ;International Journal of Chronic Obstructive Pulmonary Disease. 2018 Jul 30
9 citations
Validation of the St. George's Respiratory Questionnaire in Nepal.
Chundak T Sherpa, Steven L LeClerq, Shakuntala Singh, Neha Naithani, Raju Pangeni, Arjun Karki, Ramesh Chokhani, MeiLan K. Han, Margaret R. Gyetko, James M. Tielsch, W...> ;Chronic Obstructive Pulmonary Diseases. 2015 Sep 2
62 citations
Gender Disparities in Academic Practice.
Jennifer F. Waljee, Kate Wan Chu Chang, H. Myra Kim, Margaret R. Gyetko, Elisabeth H. Quint, Nicholas W. Lukacs, James O. Woolliscroft, Kevin C. Chung> ;Plastic and Reconstructive Surgery. 2015 Sep 1
Preparation of metagenomic DNA from bronchoalveolar lavage fluids of patients with chronic obstructive pulmonary diseases
Juan Wang, Ning Shen, Yipeng Du, John R. Erb-Downward, Gary B. Huffnagle, Margaret R. Gyetko, Bei He> ;Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica. 2014 Aug 4
3 citations
Use of Direct Gradient Analysis to Uncover Biological Hypotheses in 16S Survey Data and Beyond
John R. Erb-Downward, Amir A. Sadighi Akha, Juan Wang, Ning Shen, Bei He, Fernando J. Martinez, Margaret R. Gyetko, Jeffrey L. Curtis, Gary B. Huffnagle> ;Scientific Reports. 2012 Oct 26
61 citations
Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system.
Yashodhar P. Bhandary, Shwetha K. Shetty, Amarnath S. Marudamuthu, Margaret R. Gyetko, Steven Idell, Mehrnaz Gharaee-Kermani, Rashmi S. Shetty, Barry Starcher, Sreeram...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2012 Mar 1
24 citations
Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis.
Tsu Wei Wang, Huailin Zhang, Margaret R. Gyetko, Jack M. Parent> ;Molecular and Cellular Neurosciences. 2011 Sep 1
44 citations
Activation of Urokinase Plasminogen Activator and Its Receptor Axis Is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model
Jian Zhang, Sudha Sud, Kosuke Mizutani, Margaret R. Gyetko, Kenneth J. Pienta> ;Neoplasia. 2011 Jan 1
42 citations
Predictors of job satisfaction among academic faculty members: do instructional and clinical staff differ?
Kevin C. Chung, Jae W. Song, H. Myra Kim, James O. Woolliscroft, Elisabeth H. Quint, Nicholas W. Lukacs, Margaret R. Gyetko> ;Medical Education. 2010 Oct 1
20 citations
Induction of Tissue Factor by Urokinase in Lung Epithelial Cells and in the Lungs
Sreerama Shetty, Yashodhar P. Bhandary, Shwetha K. Shetty, Thirunavukkarasu Velusamy, Praveenkumar Shetty, Khalil Bdeir, Margaret R. Gyetko, Douglas B. Cines, Steven I...> ;American Journal of Respiratory and Critical Care Medicine. 2010 Jun 15
16 citations
The role of urokinase in idiopathic pulmonary fibrosis and implication for therapy.
Mehrnaz Gharaee-Kermani, Biao Hu, Sem H. Phan, Margaret R. Gyetko> ;Expert Opinion on Investigational Drugs. 2008 May 21
17 citations
Current and emerging drugs for idiopathic pulmonary fibrosis
Mehrnaz Gharaee-Kermani, Biao Hu, Victor J. Thannickal, Sem H. Phan, Margaret R. Gyetko> ;Expert Opinion on Emerging Drugs. 2007 Nov 5
77 citations
New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis: A Potential Role for Stem Cells in the Lung Parenchyma and Implications for Therapy
Mehrnaz Gharaee-Kermani, Margaret R. Gyetko, Biao Hu, Sem H. Phan> ;Pharmaceutical Research. 2007 Mar 1
9 citations
Mactinin treatment promotes wound-healing-associated inflammation in urokinase knockout mice.
Sharon D Luikart, Brett K. Levay-Young, Tim Hinkel, Jeffry D. Shearer, Charles D. Mills, Michael D. Caldwell, Margaret R. Gyetko, Theodore R. Oegema> ;Wound Repair and Regeneration. 2006 Mar 1
19 citations
Induction of p53 by urokinase in lung epithelial cells
Sreerama Shetty, Margaret R. Gyetko, Andrew P. Mazar> ;The Journal of Biological Chemistry. 2005 Jul 29
41 citations
Urokinase-deficient and urokinase receptor-deficient mice have impaired neutrophil antimicrobial activation in vitro.
Margaret R. Gyetko, David Aizenberg, Laura Mayo-Bond> ;Journal of Leukocyte Biology. 2004 Sep 1
38 citations
Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinase-type plasminogen activator
Andrei L. Kindzelskii, Imran Amhad, Donald Keller, Mingjie Zhou, Richard P. Haugland, B. A. Garni-Wagner, Margaret R. Gyetko, Robert F. Todd, Howard R. Petty> ;Histochemistry and Cell Biology. 2004 Mar 20
26 citations
Urokinase-deficient mice fail to generate a type 2 immune response following schistosomal antigen challenge.
Margaret R. Gyetko, Sudha Sud, Stephen W. Chensue> ;Infection and Immunity. 2004 Jan 1
86 citations
Urokinase-Type Plasminogen Activator Potentiates Lipopolysaccharide-Induced Neutrophil Activation
Edward Abraham, Margaret R. Gyetko, Katherine Kuhn, John J. Arcaroli, Derek Strassheim, Jong Sung Park, Sreerama Shetty, Steven Idell> ;Journal of Immunology. 2003 Jun 1
16 citations
Urokinase is required for the formation of mactinin, an α-actinin fragment that promotes monocyte/macrophage maturation
Sharon D Luikart, Mohammed Masri, Dan Wahl, Tim Hinkel, James M. Beck, Margaret R. Gyetko, Pankaj Gupta, Theodore R. Oegema> ;Biochimica Et Biophysica Acta. 2002 Aug 19
43 citations
Urokinase-type plasminogen activator is required for the generation of a type 1 immune response to pulmonary Cryptococcus neoformans infection.
Margaret R. Gyetko, Sudha Sud, Gwo-Hsiao Chen, Jennifer A. Fuller, Stephen W. Chensue, Galen B. Toews> ;Journal of Immunology. 2002 Jan 15
38 citations
Cutting Edge: Antigen-Driven Lymphocyte Recruitment to the Lung Is Diminished in the Absence of Urokinase-Type Plasminogen Activator (uPA) Receptor, but Is Independent...
Margaret R. Gyetko, Sudha Sud, Joanne Sonstein, Timothy Polak, Anchal Sud, Jeffrey L. Curtis> ;Journal of Immunology. 2001 Nov 15
171 citations
Urokinase Receptor-Deficient Mice Have Impaired Neutrophil Recruitment in Response to Pulmonary Pseudomonas aeruginosa Infection
Margaret R. Gyetko, Sudha Sud, Tara Kendall, Jennifer A. Fuller, Michael W. Newstead, Theodore J. Standiford> ;Journal of Immunology. 2000 Aug 1
27 citations
Urokinase is required for T lymphocyte proliferation and activation in vitro
Margaret R. Gyetko, Eric A. Libre, Jennifer A. Fuller, Gwo Hsiao Chen, Galen B. Toews> ;The Journal of Laboratory and Clinical Medicine. 1999 Mar 1
30 citations
Urokinase-Type Plasminogen Activator in Inflammatory Cell Recruitment and Host Defense against Pneumocystis carinii in Mice
James M. Beck, Angela M. Preston, Margaret R. Gyetko> ;Infection and Immunity. 1999 Feb 1
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Press Mentions

Supporting Black Voices in UrologyDecember 14th, 2020

Grant Support

The Role Of Urokinase In Lung T Lymphocyte ResponsesNational Heart, Lung, And Blood Institute2000–2003
Molecular Mechanisms Of Monocyte ChemotaxisNational Heart, Lung, And Blood Institute1995–1998