MargaretKOffermannMDPhD

Oncology • Atlanta, GA

CEO, OncoSpherix, Inc

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Office
7935 Fawndale Way
Atlanta, GA 30350
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1984 - 1987
University of ChicagoResidency, Internal Medicine, 1981 - 1984
Virginia Commonwealth University School of MedicineClass of 1980

Certifications & Licensure

GA State Medical License 1989 - 2025
IL State Medical License 1981 - 1987
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

President Federation of American Societies for Experimental Biology, 2013-2014
Executive committee Georgia Global Health Alliance
Alpha Omega Alpha Medical Honor Society Alpha Omega Alpha, 2014
Commencement Speaker, Bryan University Program in Applied Healthcare Informatics Bryan Unversity, 2014
Board of Directors Georgia Center for Oncology Research and Education, 2007-2013
Charlotte Haywood Endowed Lecturer in the Biologic Sciences Mount Holyoke College, 2010
Board of Directors, ex officio Georgia Bio, 2006-2010
Community Service Award Georgia Bio, 2008
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Publications & Presentations

PubMed

4 citations
Biomarkers and Sustainable Innovation in Cardiovascular Drug Development: Lessons from Near and Far Afield
Russell M. Medford, T. Forcht Dagi, Robert S. Rosenson, Margaret K. Offermann> ;Current Atherosclerosis Reports. 2013 Mar 20
2 citations
The era of targeted therapies.
Margaret Offermann> ;American Family Physician. 2008 Feb 1
18 citations
Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells.
Bryan D. Shelby, Heather L. LaMarca, Harris E. McFerrin, Anne B. Nelson, Joseph A. Lasky, Gang Sun, Leslie Myatt, Margaret K. Offermann, Cindy A. Morris, Deborah E. Su...> ;Virology Journal. 2007 Sep 14
40 citations
Human herpesvirus 8 presence and viral load are associated with the progression of AIDS-associated Kaposi's sarcoma
A. Scott Laney, Michael J. Cannon, Harold W. Jaffe, Margaret K. Offermann, Chin-Yih Ou, Kay Radford, Mitesh Patel, Thomas J. Spira, Clifford J. Gunthel, Philip E. Pell...> ;AIDS. 2007 Jul 31
43 citations
Targeting human herpesvirus-8 for treatment of Kaposi's sarcoma and primary effusion lymphoma.
Carmen M. Klass, Margaret K. Offermann> ;Current Opinion in Oncology. 2005 Sep 1
42 citations
Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus.
Matam Vijay-Kumar, Jon R. Gentsch, William J. Kaiser, Niels Borregaard, Margaret K. Offermann, Andrew S. Neish, Andrew T. Gewirtz> ;Journal of Immunology. 2005 May 15
290 citations
Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif.
William J. Kaiser, Margaret K. Offermann> ;Journal of Immunology. 2005 Apr 15
59 citations
The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.
Carmen M. Klass, Laurie T. Krug, Veronika P. Pozharskaya, Margaret K. Offermann> ;Blood. 2005 May 15
24 citations
Inhibition of infectious human herpesvirus 8 production by gamma interferon and alpha interferon in BCBL-1 cells.
Veronika P. Pozharskaya, Laura L. Weakland, Margaret K. Offermann> ;The Journal of General Virology. 2004 Oct 1
27 citations
Repeated measures study of human herpesvirus 8 (HHV-8) DNA and antibodies in men seropositive for both HHV-8 and HIV.
A. Scott Laney, Sheila C. Dollard, Harold W. Jaffe, Margaret K. Offermann, Thomas J. Spira, Clifford J. Gunthel, Philip E. Pellett, Michael J. Cannon> ;AIDS. 2004 Sep 3
26 citations
Inhibition of Infection and Replication of Human Herpesvirus 8 in Microvascular Endothelial Cells by Alpha Interferon and Phosphonoformic Acid
Laurie T. Krug, Veronika P. Pozharskaya, Yimin Yu, Naoki Inoue, Margaret K. Offermann> ;Journal of Virology. 2004 Aug 1
37 citations
Short Duration of Elevated vIRF-1 Expression during Lytic Replication of Human Herpesvirus 8 Limits Its Ability To Block Antiviral Responses Induced by Alpha Interfero...
Veronika P. Pozharskaya, Laura L. Weakland, James C. Zimring, Laurie T. Krug, Elizabeth R. Unger, Andrew Neisch, Harish C. Joshi, Naoki Inoue, Margaret K. Offermann> ;Journal of Virology. 2004 Jun 15
49 citations
IFN-α Sensitizes Human Umbilical Vein Endothelial Cells to Apoptosis Induced by Double-Stranded RNA
William J. Kaiser, Jonathan L. Kaufman, Margaret K. Offermann> ;Journal of Immunology. 2004 Feb 1
51 citations
Characterization of Entry Mechanisms of Human Herpesvirus 8 by Using an Rta-Dependent Reporter Cell Line
Naoki Inoue, Jörn Winter, Renu B. Lal, Margaret K. Offermann, Shin Koyano> ;Journal of Virology. 2003 Jul 15
69 citations
Risk factors for Kaposi's sarcoma in men seropositive for both human herpesvirus 8 and human immunodeficiency virus.
Michael J. Cannon, Sheila C. Dollard, Jodi B Black, Brian R. Edlin, Connie Hannah, Susan E Hogan, Mitesh Patel, Harold W. Jaffe, Margaret K. Offermann, Thomas J. Spira...> ;AIDS. 2003 Jan 24
21 citations
Activation of cellular and heterologous promoters by the human herpesvirus 8 replication and transcription activator.
Florence Roan, Naoki Inoue, Margaret K. Offermann> ;Virology. 2002 Sep 30
7 citations
Induction of Human Herpesvirus 8 Gene Expression in a Post-transplantation Primary Effusion Lymphoma Cell Line
Renee N. Shaw, Edmund K. Waller, Margaret K. Offermann> ;Leukemia & Lymphoma. 2002 Mar 1
18 citations
Multiple signaling cascades are differentially involved in gene induction by double stranded RNA in interferon-α-primed cells
Jennifer L. Harcourt, Margaret K. Offermann> ;European Journal of Biochemistry. 2001 Mar 1
27 citations
Modulation of double-stranded RNA-mediated gene induction by interferon in human umbilical vein endothelial cells.
Jennifer L. Harcourt, M. Kelly Hagan, Margaret K. Offermann> ;Journal of Interferon & Cytokine Research. 2000 Nov 1
55 citations
Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells.
Renee N. Shaw, Jack L. Arbiser, Margaret K. Offermann> ;AIDS. 2000 May 5
17 citations
Interferon-α synergistically enhances induction of interleukin-6 by double stranded RNA in HeLa cells
Jennifer L. Harcourt, Margaret K. Offermann> ;European Journal of Biochemistry. 2000 May 1
3 citations
Interleukin 1β induces expression of human herpesvirus 8 encoded genes in BCBL-1 cells
Yimin Yu, Florence Roan, Margaret K. Offermann> ;AIDS. 1999 Oct 22
7 citations
Lack of Responsiveness of a Nuclear Factor-κB-Regulated Promoter to Transactivation by Human Immunodeficiency Virus 1 Tat in HeLa Cells
Gloria D. Kelly, Cindy B. Morris, Margaret K. Offermann> ;Virology. 1999 Oct 10
8 citations
Consideration of host-viral interactions in the pathogenesis of Kaposi's sarcoma.
Margaret K. Offermann> ;Journal of Acquired Immune Deficiency Syndromes. 1999 Aug 1
24 citations
Transcriptional activation by the human herpesvirus-8-encoded interferon regulatory factor.
Florence Roan, James C. Zimring, Stephen Goodbourn, Margaret K. Offermann> ;The Journal of General Virology. 1999 Aug 1
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Grant Support

Subversion Of Host Antiviral Defenses By HHV8 VirfNational Cancer Institute1998–2002
Molecular Events In The Pathogenesis Of Kaposi'S SarcomaNational Cancer Institute1996–1999
Cytokine And Adhesion Molecule Expression In Kaposi'SNational Cancer Institute1995–1996
Molecular Events In The Pathogenesis Of Kaposis SarcomaNational Cancer Institute1995
Cytokine And Adhesion Molecule Expression In KaposisNational Cancer Institute1994
HTLV Trans Activator Genes And Cellular Gene ExpressionNational Cancer Institute1986–1988

MargaretKOffermannMDPhD

Dr. Offermann is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Publications & Presentations

Grant Support

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