MargaretCShuhartMD

PubMed

• 23 citations
  Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV I...
  Mayur Brahmania, Manuel Lombardero, Bettina E. Hansen, Norah A. Terrault, Anna S. Lok, Robert P. Perrillo, Steven H. Belle, Adrian M. Di Bisceglie, Jordan J. Feld, Wil...> ;Clinical Gastroenterology and Hepatology. 2019 Nov 1
• 20 citations
  Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B.
  Kyong-Mi Chang, Daniel Traum, Jang-June Park, Suzanne Ho, Keisuke Ojiro, David Wong, Abdus S. Wahed, Norah A. Terrault, Mandana Khalili, Richard K. Sterling, Harry L.A...> ;Plos Pathogens. 2019 Apr 18
• 13 citations
  Hepatocellular carcinoma among US and non-US-born patients with chronic hepatitis B: Risk factors and age at diagnosis
  Kaitlyn Kennedy, Susan M. Graham, Nayan Arora, Margaret C. Shuhart, H. Nina Kim> ;Plos One. 2018 Sep 25
• 18 citations
  Relationship Between Metabolic Syndrome, Alanine Aminotransferase Levels, and Liver Disease Severity in a Multiethnic North American Cohort With Chronic Hepatitis B
  Mandana Khalili, Margaret C. Shuhart, Manuel Lombardero, Jordan J. Feld, David E. Kleiner, Raymond T. Chung, Norah A. Terrault, Mauricio Lisker-Melman, Arun J. Sanyal,...> ;Diabetes Care. 2018 Mar 29
• 78 citations
  Characteristics of adults in the hepatitis B research network in North America reflect their country of origin and hepatitis B virus genotype.
  Marc G. Ghany, Robert P. Perrillo, Ruosha Li, Steven H. Belle, Harry L.A. Janssen, Norah A. Terrault, Margaret C. Shuhart, Daryl T.-Y. Lau, W. Ray Kim, Michael W. Frie...> ;Clinical Gastroenterology and Hepatology. 2015 Jan 1
• 204 citations
  Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfection.
  Mark S. Sulkowski, Susanna Naggie, Jacob Lalezari, Walford Jeffrey Fessel, Karam Mounzer, Margaret C. Shuhart, Anne F Luetkemeyer, David M. Asmuth, Anuj Gaggar, Liyun ...> ;JAMA. 2014 Jul 23
• 45 citations
  Enhancement of hepatic 4‐hydroxylation of 25‐hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: Implications for drug‐induced osteomalacia
  Zhican Wang, Yvonne S. Lin, Leslie J. Dickmann, Emma Jane Poulton, David L. Eaton, Johanna W. Lampe, Danny D. Shen, Connie L. Davis, Margaret C. Shuhart, Kenneth E. Th...> ;Journal of Bone and Mineral Research. 2013 May 1
• 31 citations
  Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo.
  Emma Jane Poulton, Lisa Levy, Johanna W. Lampe, Danny D. Shen, Julia H. Tracy, Margaret C. Shuhart, Kenneth E. Thummel, David L. Eaton> ;Toxicology and Applied Pharmacology. 2013 Jan 1
• 20 citations
  Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D3 function in human colon adenocarcinoma LS180 cells
  Xi Emily Zheng, Zhican Wang, Michael Z. Liao, Yvonne S. Lin, Margaret C. Shuhart, Erin G. Schuetz, Kenneth E. Thummel> ;Biochemical Pharmacology. 2012 Aug 1
• 17 citations
  Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.
  Angela L. Rasmussen, I-Ming Wang, Margaret C. Shuhart, Sean Proll, Yudong He, Razvan Cristescu, Christopher J. Roberts, Victoria S. Carter, Christopher M. Williams, De...> ;Virology. 2012 Aug 15
• 11 citations
  Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection.
  Hui Li, Elizabeth Atkins, Joseph J. Bruckner, Susan McArdle, Wan Chong Qiu, Lisa V. Thomassen, John D. Scott, Margaret C. Shuhart, Stephen Livingston, Lisa Townshend-B...> ;Virology. 2012 Feb 5
• 24 citations
  Use of the AST to platelet ratio index in HCV/HIV co-infected patients
  Amit G. Singal, Lisa V. Thomassen, David R. Gretch, Margaret C. Shuhart> ;Alimentary Pharmacology & Therapeutics. 2011 Mar 1
• 100 citations
  Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1
  Sampa Pal, Stephen J. Polyak, Nazneen Bano, Wan Chong Qiu, Robert L. Carithers, Margaret C. Shuhart, David R. Gretch, Aditi Das> ;Journal of Gastroenterology and Hepatology. 2010 Mar 1
• 78 citations
  Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection.
  Chihiro Morishima, Margaret C. Shuhart, Chia C. Wang, Denise M. Paschal, Minjun C. Apodaca, Yanze Liu, Derek D. Sloan, Tyler N. Graf, Nicholas H. Oberlies, David Y.W. ...> ;Gastroenterology. 2010 Feb 1
• 22 citations
  Reduced Duodenal Cytochrome P450 3A Protein Expression and Catalytic Activity in Patients With Cirrhosis
  Donavon J. McConn, Yvonne S. Lin, Terri L. Mathisen, David K. Blough, Yang Xu, Takanori Hashizume, Shari L. Taylor, Kenneth E. Thummel, Margaret C. Shuhart> ;Clinical Pharmacology and Therapeutics. 2009 Apr 1
• 31 citations
  Factors predictive of significant hepatic fibrosis in adults with chronic hepatitis B and normal serum ALT.
  Chia C. Wang, Lei Y. Lim, Heike Deubner, Kenneth Tapia, Agnes W.Y. Lau, Jaime Manansala, Meighan Krows, Margaret C. Shuhart, Kris V. Kowdley> ;Journal of Clinical Gastroenterology. 2008 Aug 1
• 23 citations
  Identification of Human UDP-glucuronosyltransferases Catalyzing Hepatic 1α,25-Dihydroxyvitamin D3 Conjugation
  Takanori Hashizume, Yang Xu, Michael A. Mohutsky, Jeffrey J. Alberts, Chad E. Hadden, Thomas F. Kalhorn, Nina Isoherranen, Margaret C. Shuhart, Kenneth E. Thummel> ;Biochemical Pharmacology. 2008 Mar 1
• 6 citations
  Case Report: Hepatitis C Virus Activation in HIV-Infected Patients Initiating Highly Active Antiretroviral Therapy
  H. Nina Kim, Robert D. Harrington, Margaret C. Shuhart, Linda S. Cook, Chihiro Morishima, Keith R. Jerome, Chia C. Wang> ;AIDS Patient Care and Stds. 2007 Oct 20
• 8 citations
  Preservation of Intrahepatic Hepatitis C Virus (HCV)-Specific CD4+ T Cell Responses despite Global Loss of CD4+ T Cells in HCV/HIV Coinfection
  Chihiro Morishima, Margaret C. Shuhart, Christina S. Yoshihara, Denise M. Paschal, Melissa A. Silva, Lisa V. Thomassen, Scott S. Emerson, David R. Gretch> ;The Journal of Infectious Diseases. 2007 Aug 15
• 142 citations
  Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin
  Stephen J. Polyak, Chihiro Morishima, Margaret C. Shuhart, Chia C. Wang, Yanze Liu, David Y.W. Lee> ;Gastroenterology. 2007 May 1
• 13 citations
  EUS-guided FNA diagnosis of pancreatic tuberculosis.
  Raymond Cheng, Verena S. Grieco, Margaret C. Shuhart, Stephen J. Rulyak> ;Gastrointestinal Endoscopy. 2006 Oct 1
• 31 citations
  HIV Infection and Antiretroviral Therapy: Effect on Hepatitis C Virus Quasispecies Variability
  Margaret C. Shuhart, Daniel G. Sullivan, Kirubeal Bekele, Robert D. Harrington, Mari M. Kitahata, Terri L. Mathisen, Lisa V. Thomassen, Scott S. Emerson, David R. Gretch> ;The Journal of Infectious Diseases. 2006 May 1
• 20 citations
  Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals.
  Kathie-Anne Walters, Maria W. Smith, Sampa Pal, Jill C. Thompson, Matthew J. Thomas, Matthew M. Yeh, David L. Thomas, Matthew Fitzgibbon, Sean Proll, Nelson Fausto, Da...> ;Virology. 2006 Jul 5
• 135 citations
  Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing.
  Chihiro Morishima, Denise M. Paschal, Chia C. Wang, Christina S. Yoshihara, Brent L. Wood, Anthony E. T. Yeo, Scott S. Emerson, Margaret C. Shuhart, David R. Gretch> ;Hepatology. 2006 Mar 1
• 37 citations
  Intrahepatic hepatitis C virus replication correlates with chronic hepatitis C disease severity in vivo.
  Sampa Pal, Margaret C. Shuhart, Lisa V. Thomassen, Scott S. Emerson, Tao Su, Nathan A. Feuerborn, John Kae, David R. Gretch> ;Journal of Virology. 2006 Mar 1
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