MariosGiannakisMDPh.D

PubMed

• Alcohol and colorectal cancer risk subclassified by mutational signatures of DNA mismatch repair deficiency.
  Aiping Fang, Tomotaka Ugai, Carino Gurjao, Rong Zhong, Zhenhua Liu, Xinyuan Zhang, Peilu Wang, Molin Wang, Xuehong Zhang, Edward Giovannucci, Jonathan Nowak, Marios Gi...> ;Journal of the National Cancer Institute. 2024 Apr 4
• Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature.
  Claire E Thomas, Peter Georgeson, Conghui Qu, Robert S Steinfelder, Daniel D Buchanan, Mingyang Song, Tabitha A Harrison, Caroline Y Um, Meredith A Hullar, Mark A Jenk...> ;Cancer Epidemiology, Biomarkers & Prevention. 2024 Apr 3
• Identifying regulators of aberrant stem cell and differentiation activity in colorectal cancer using a dual endogenous reporter system.
  Sandor Spisak, David Chen, Pornlada Likasitwatanakul, Paul Doan, Zhixin Li, Pratyusha Bala, Laura Vizkeleti, Viktoria Tisza, Pushpamali De Silva, Marios Giannakis, Bri...> ;Nature Communications. 2024 Mar 12
• Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses.
  Nikos Papadimitriou, Conghui Qu, Tabitha A Harrison, Alaina M Bever, Richard M Martin, Konstantinos K Tsilidis, Polly A Newcomb, Stephen N Thibodeau, Christina C Newto...> ;Ebiomedicine. 2024 Mar 1
• Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk.
  Mariana C Stern, Joel Sanchez Mendez, Andre E Kim, Mireia Obón-Santacana, Ferran Moratalla-Navarro, Vicente Martín, Victor Moreno, Yi Lin, Stephanie A Bien, Conghui Qu...> ;Cancer Epidemiology, Biomarkers & Prevention. 2024 Mar 1
• RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer.
  Singh, H., Sahgal, P., Kapner, K., Corsello, S., Gupta, H., Gujrathi, R., Li, Y., Cherniack, A., El Alam, R., Kerfoot, J., Andrews, E., Lee, A., Nambiar, C., Hannigan,...> ;Clinical Cancer Research. 2024 Feb 12
• Cancer Diagnoses After Recent Weight Loss.
  Wang, Q., Babic, A., Rosenthal, M., Lee, A., Zhang, Y., Zhang, X., Song, M., Rezende, L., Lee, D., Biller, L., Ng, K., Giannakis, M., Chan, A., Meyerhardt, J., Fuchs, ...> ;JAMA. 2024 Jan 23
• Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma.
  Takashima, Y., Kawamura, H., Okadome, K., Ugai, S., Haruki, K., Arima, K., Mima, K., Akimoto, N., Song, M., Ugai, T., Nowak, J., Giannakis, M., Garrett, W., Sears, C.,...> ;Clinical Microbiology and Infection. 2024 Jan 22
• Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer.
  Sandor Spisak, David Chen, Pornlada Likasitwatanakul, Paul Doan, Zhixin Li, Pratyusha Bala, Laura Vizkeleti, Viktoria Tisza, Pushpamail De Silva, Marios Giannakis, Bri...> ;Biorxiv. 2024 Jan 17
• 1 citations
  A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Ad...
  Huffman, B., Feng, H., Parmar, K., Wang, J., Kapner, K., Kochupurakkal, B., Martignetti, D., Sadatrezaei, G., Abrams, T., Biller, L., Giannakis, M., Ng, K., Patel, A.,...> ;Clinical Cancer Research. 2023 Dec 15
• Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts.
  Shanshan Shi, Kai Wang, Tomotaka Ugai, Marios Giannakis, Jules Cazaubiel, Andrew T Chan, Edward L Giovannucci, Jonathan A Nowak, Jeffrey A Meyerhardt, Shuji Ogino, Min...> ;British Journal of Cancer. 2023 Nov 1
• 3 citations
  Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer.
  Harshabad Singh, Rachel B Keller, Kevin S Kapner, Julien Dilly, Srivatsan Raghavan, Chen Yuan, Elizabeth F Cohen, Michael Tolstorukov, Elizabeth Andrews, Lauren K Brai...> ;Clinical Cancer Research. 2023 Nov 14
• 2 citations
  Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data.
  Melissa Zhao, Mai Chan Lau, Koichiro Haruki, Juha P Väyrynen, Carino Gurjao, Sara A Väyrynen, Andressa Dias Costa, Jennifer Borowsky, Kenji Fujiyoshi, Kota Arima, Tsuy...> ;NPJ Precision Oncology. 2023 Jun 10
• Highly Sensitive Circulating Tumor DNA Assay Aids Clinical Management of Radiographically Occult Isolated Peritoneal Metastases in Patients With GI Cancer.
  Harshabad Singh, Samuel J Klempner, Nelya Melnitchouk, Deepak P Chander, Ovidiu George Negrea, Anuj K Patel, Benjamin L Schlechter, Douglas A Rubinson, Brandon M Huffm...> ;JCO Precision Oncology. 2023 Jun 1
• 13 citations
  Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients.
  Pei-Chen Tsai, Tsung-Hua Lee, Kun-Chi Kuo, Fang-Yi Su, Tsung-Lu Michael Lee, Eliana Marostica, Tomotaka Ugai, Melissa Zhao, Mai Chan Lau, Juha P Väyrynen, Marios Giann...> ;Nature Communications. 2023 Apr 13
• 4 citations
  A common cancer at an uncommon age.
  Marios Giannakis, Kimmie Ng> ;Science. 2023 Mar 17
• 3 citations
  Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.
  Peter Georgeson, Robert S Steinfelder, Tabitha A Harrison, Bernard J Pope, Syed H Zaidi, Conghui Qu, Yi Lin, Jihoon E Joo, Khalid Mahmood, Mark Clendenning, Romy Walke...> ;Medrxiv. 2024 Jan 30
• 3 citations
  Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.
  Kimberly Perez, Anna M Chiarella, James M Cleary, Nora Horick, Colin Weekes, Thomas Abrams, Lawrence Blaszkowsky, Peter Enzinger, Marios Giannakis, Lipika Goyal, Jeffr...> ;The Oncologist. 2023 May 8
• 5 citations
  Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases.
  Tomotaka Ugai, Koichiro Haruki, Tabitha A Harrison, Yin Cao, Conghui Qu, Andrew T Chan, Peter T Campbell, Naohiko Akimoto, Sonja Berndt, Hermann Brenner, Daniel D Buch...> ;The American Journal of Gastroenterology. 2023 Apr 1
• 24 citations
  Combined PD-1, BRAF and MEK inhibition in BRAFcolorectal cancer: a phase 2 trial.
  Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian Hess, Kelly Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, To...> ;Nature Medicine. 2023 Feb 1
• 6 citations
  Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases.
  Tomotaka Ugai, Naohiko Akimoto, Koichiro Haruki, Tabitha A Harrison, Yin Cao, Conghui Qu, Andrew T Chan, Peter T Campbell, Sonja I Berndt, Daniel D Buchanan, Amanda J ...> ;Journal of Gastroenterology. 2023 Mar 1
• 2 citations
  Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer.
  Rachel B Keller, Tali Mazor, Lynette Sholl, Andrew J Aguirre, Harshabad Singh, Nilay Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor Hennessey, M...> ;JCO Precision Oncology. 2023 Jan 1
• Inverse relationship betweenamount and tumor CD274 (PD-L1) expression in colorectal carcinoma.
  Tomotaka Ugai, Takashi Shimizu, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Genki Usui, Juha P Väyrynen, Kazuo Okadome, Koichiro Haruki, Naohiko Akimoto, Yohe...> ;Clinical & Translational Immunology. 2023 Jan 1
• 3 citations
  Clinical and Genomic Characterization of Interval Colorectal Cancer in 3 Prospective Cohorts.
  Yang, K., Cao, Y., Gurjao, C., Liu, Y., Guo, C., Lo, C., Zong, X., Drew, D., Geraghty, C., Prezioso, E., Moore, M., Williams, C., Riley, T., Saul, M., Ogino, S., Giann...> ;Gastroenterology. 2022 Dec 1
• 8 citations
  Body mass index and molecular subtypes of colorectal cancer.
  Neil Murphy, Christina C Newton, Mingyang Song, Nikos Papadimitriou, Michael Hoffmeister, Amanda I Phipps, Tabitha A Harrison, Polly A Newcomb, Elom K Aglago, Sonja I ...> ;Journal of the National Cancer Institute. 2023 Feb 8
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