MarisaRoseNucciMD

Pathology • Boston, MA

Anatomic Pathology, Clinical Pathology

Associate Professor of Pathology, Brigham and Women's Hospital

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Office
75 Francis Street Amory 3
Brigham And Womens Hospital Department Of Pathology
Boston, MA 02115
Phone+1 617-732-7530
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Education & Training

Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1992 - 1997
Johns Hopkins University School of MedicineClass of 1992

Certifications & Licensure

MA State Medical License 1996 - 2025
American Board of Pathology Anatomic Pathology

Publications & Presentations

PubMed

Uterine Leiomyosarcoma Associated With Perivascular Epithelioid Cell Tumor: A Phenomenon of Differentiation/Dedifferentiation and Evidence Suggesting Cell-of-Origin.
Henrietta C Eugene, Hiro Nonogaki, John M Gross, Russell Vang, Levon Katsakhyan, Maryam Shahi, Marisa R Nucci, Deyin Xing> ;The American Journal of Surgical Pathology. 2024 Mar 18
Sarcomas With RAD51B Fusions Are Associated With a Heterogeneous Phenotype.
Chang, H., Dickson, B., Torrence, D., Kirchner, M., Stenzinger, A., Mechtersheimer, G., Dermawan, J., Sharma, A., Turashvili, G., Nucci, M., Chiang, S., Oliva, E., Ant...> ;Modern Pathology. 2024 Feb 1
Malignant female genital tract smooth muscle tumors with adipocytic differentiation: A morphologic, immunohistochemical, MDM2 fluorescence in situ hybridization and mo...
Amy A Swanson, Michael Michal, Deyin Xing, Nooshin K Dashti, Vladimir Židlík, E Heidi Cheek-Norgan, Matthew E Keeney, Gary L Keeney, William R Sukov, Sounak Gupta, Mar...> ;Human Pathology. 2024 Jan 1
Benign female genital tract smooth muscle tumors with adipocytic differentiation: A morphologic, immunohistochemical and MDM2 fluorescence in situ hybridization study ...
Amy A Swanson, Michael Michal, Deyin Xing, Vladimir Židlík, E Heidi Cheek-Norgan, Matthew E Keeney, Gary L Keeney, William R Sukov, Sounak Gupta, Marisa R Nucci, J Ken...> ;Human Pathology. 2023 Dec 1
4 citations
FIGO 2023 endometrial cancer staging: too much, too soon?
W Glenn McCluggage, Tjalling Bosse, C Blake Gilks, Brooke E Howitt, Jessica N McAlpine, Marisa R Nucci, Joseph T Rabban, Naveena Singh, Karen L Talia, Carlos Parra-Herran> ;International Journal of Gynecological Cancer. 2023 Nov 7
Pattern A endocervical adenocarcinomas with ovarian metastasis are indolent and molecularly distinct from destructively invasive adenocarcinomas.
Alexander J Neil, Yvonne Y Li, Ardeshir Hakam, Marisa R Nucci, Carlos Parra-Herran> ;Histopathology. 2024 Jan 1
1 citations
Targeted RNA Sequencing Highlights a Diverse Genomic and Morphologic Landscape in Low-grade Endometrial Stromal Sarcoma, Including Novel Fusion Genes.
Marisa R Nucci, Gulisa Turashvili, Sharon J Song, Sophie Corbett-Burns, Matthew Cesari, Martin C Chang, Blaise Clarke, Elizabeth Demicco, Valerie Dube, Cheng-Han Lee, ...> ;The American Journal of Surgical Pathology. 2024 Jan 1
3 citations
Expanding the Clinicopathologic and Molecular Spectrum of Lipoblastoma-Like Tumor in a Series of 28 Cases.
William J Anderson, Adrian Mariño-Enríquez, Kiril Trpkov, Jason L Hornick, Marisa R Nucci, Brendan C Dickson, Christopher D M Fletcher> ;Modern Pathology. 2023 Oct 1
1 citations
Genomic profiling of dedifferentiated endometrial carcinomas arising in the background of high-grade carcinoma: a targeted next-generation sequencing study.
Ekaterina Olkhov-Mitsel, Aurelia Busca, Carlos Parra-Herran, Yutaka Amemiya, Sharon Nofech-Mozes, Bojana Djordjevic, Marisa R Nucci, Arun Seth, Jelena Mirkovic> ;Histopathology. 2023 Sep 1
Localized Endometrial Proliferations of Pregnancy are Clonal Glandular Outgrowths Characterized by PTEN Loss and PIK3CA Pathogenic Variants.
Cindy Wepy, David B Chapel, George L Mutter, Bradley J Quade, Marisa R Nucci, Carlos Parra-Herran> ;Modern Pathology. 2023 Aug 1
1 citations
Molecular correlates of invasion pattern in HPV-associated endocervical adenocarcinoma: emergence of two distinct risk-stratified tiers.
Aarti E Sharma, Anjelica J Hodgson, Brooke E Howitt, Ekaterina Olkhov-Mitsel, Bojana Djordevic, Kay J Park, Marisa R Nucci, Carlos Parra-Herran> ;Histopathology. 2023 Jun 1
3 citations
Molecular Landscape of Mullerian Clear Cell Carcinomas Identifies The Cancer Genome Atlas-like Prognostic Subgroups.
Lina Irshaid, Danielle C Costigan, Fei Dong, Ursula A Matulonis, Marisa R Nucci, David L Kolin> ;Modern Pathology. 2023 May 1
3 citations
Reply to Comment on HPV-independent, p53-Wild-type Vulvar Intraepithelial Neoplasia: A Review of Nomenclature and the Journey to Characterize Acanthotic Precursor Lesi...
Carlos Parra-Herran, Marisa R Nucci, Naveena Singh, Natalia Rakislova, Brooke E Howitt, Lynn Hoang, C Blake Gilks, Tjalling Bosse, Jaclyn C Watkins> ;Modern Pathology. 2023 Feb 1
3 citations
Dedifferentiated leiomyosarcoma of the uterus: a clinicopathologic and immunohistochemical analysis of 23 cases.
David B Chapel, Livia Maccio, Emma Bragantini, Gian F Zannoni, Bradley J Quade, Carlos Parra-Herran, Marisa R Nucci> ;Histopathology. 2023 May 1
12 citations
Evaluation of Treatment With Talazoparib and Avelumab in Patients With Recurrent Mismatch Repair Proficient Endometrial Cancer.
Panagiotis A Konstantinopoulos, Allison A Gockley, Niya Xiong, Carolyn Krasner, Neil Horowitz, Susana Campos, Alexi A Wright, Joyce F Liu, Meghan Shea, Oladapo Yeku, C...> ;JAMA Oncology. 2022 Sep 1
2 citations
Low-grade Fibromyxoid Sarcoma of the Vulva and Vagina: Clinical, Pathologic, and Molecular Characterization of 7 Cases and Review of the Literature.
Danielle Costigan, Paola Dal Cin, Christopher D M Fletcher, Marisa R Nucci, Carlos Parra-Herran, David B Chapel> ;The American Journal of Surgical Pathology. 2022 Sep 1
2 citations
Ovarian Signet-ring Stromal Tumor: A Morphologic, Immunohistochemical, and Molecular Study of 7 Cases With Discussion of the Differential Diagnosis.
Nairi Tchrakian, Esther Oliva, Anne-Sophie Chong, Barbara Rivera-Polo, Jennifer A Bennett, Marisa R Nucci, Shatrughan Sah, J Kenneth Schoolmeester, Rachael A van der G...> ;The American Journal of Surgical Pathology. 2022 Dec 1
6 citations
Addressing the diagnostic and therapeutic dilemmas of ovarian immature teratoma: Report from a clinicopathologic consensus conference.
Farzana Pashankar, Krisztina Hanley, Michelle Lockley, Sara Stoneham, Marisa R Nucci, Miguel Reyes-Múgica, Esther Elishaev, Russell Vang, Jennifer Veneris, Heather Ryt...> ;European Journal of Cancer. 2022 Sep 1
10 citations
NTRK -Rearranged Uterine Sarcomas: Clinicopathologic Features of 15 Cases, Literature Review, and Risk Stratification.
Danielle C Costigan, Marisa R Nucci, Brendan C Dickson, Martin C Chang, Sharon Song, Lynette M Sholl, Jason L Hornick, Christopher D M Fletcher, David L Kolin> ;The American Journal of Surgical Pathology. 2022 Oct 1
6 citations
A novel morphology-based risk stratification model for stage I uterine leiomyosarcoma: an analysis of 203 cases.
David B Chapel, Aarti Sharma, Ricardo R Lastra, Livia Maccio, Emma Bragantini, Gian Franco Zannoni, Suzanne George, Bradley J Quade, Carlos Parra-Herran, Marisa R Nucci> ;Modern Pathology. 2022 Jun 1
16 citations
HPV-independent, p53-wild-type vulvar intraepithelial neoplasia: a review of nomenclature and the journey to characterize verruciform and acanthotic precursor lesions ...
Carlos Parra-Herran, Marisa R Nucci, Naveena Singh, Natalia Rakislova, Brooke E Howitt, Lynn Hoang, C Blake Gilks, Tjalling Bosse, Jaclyn C Watkins> ;Modern Pathology. 2022 Oct 1
2 citations
Atypical uterine polyps show morphologic and molecular overlap with mullerian adenosarcoma but follow a benign clinical course.
David Chapel, Brooke E. Howitt, Lynette M. Sholl, Paola Dal Cin, Marisa R. Nucci> ;Modern Pathology. 2021 Oct 21
9 citations
Epithelioid Leiomyosarcoma of the Uterus: Modern Outcome-based Appraisal of Diagnostic Criteria in a Large Institutional Series.
David B. Chapel, Marisa R. Nucci, Bradley J. Quade, Carlos Parra-Herran> ;The American Journal of Surgical Pathology. 2021 Aug 23
Next-Generation Sequencing in the Diagnosis of Metastatic Lesions: Reclassification of a Glioblastoma as an Endometrial Cancer Metastasis to the Brain.
Shuk On Annie Leung, Olivia Foley, David Chapel, Annacarolina da Silva, Marisa R. Nucci, Michael G. Muto, Susana M. Campos> ;The Oncologist. 2021 Aug 26
7 citations
Interobserver reproducibility of the diagnosis of differentiated exophytic vulvar intraepithelial lesion (DEVIL) and the distinction from its mimics.
Grace Neville, David B. Chapel, Christopher P. Crum, Sharon Song, Ju-Yoon Yoon, Kenneth R. Lee, David L. Kolin, Michelle S. Hirsch, Marisa R. Nucci, Carlos Parra-Herran> ;Histopathology. 2021 Jul 2
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Journal Articles

Original Contribution Clinicopathologic and Immunohistochemical Features of Uterine Adenomyomatous Polyps☆
Bradley J Quade, Brooke E Howitt, Marisa R Nucci, Kyle C Strickland, ScienceDirect

Lectures

Common Challenges in Gynecologic and Obstetric Pathology: The 19th Annual Tutorial in Gynecologic and Obstetric Pathology
Harvard Medical School, Boston, Massachusetts - 10/27/2012
Interpreting the Endometrial Biopsy: A Multimedia Microscopic Tutorial
Harvard Medical School, Boston, Massachusetts - 11/19/2011

Hospital Affiliations

Brigham and Women's HospitalBoston, Massachusetts