MarkS.ButlerMD

PubMed

• 30 citations
  Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition.
  Shahadat Hossan, Zi Yang Chan, Hilary M. Collins, Fiona Natalia Shipton, Mark S. Butler, Mohammed Rahmatullah, Jong Bong Lee, Pavel Gershkovich, Leonid Kagan, Teng-Jin...> ;Cancer Letters. 2019 Jul 1
• 30 citations
  Evidence against a role for NLRP3-driven islet inflammation in db/db mice.
  Helene L. Kammoun, Tamara L Allen, Darren C. Henstridge, S. Barre, Rebecca C. Coll, Graeme I. Lancaster, Lena Cron, Saskia Reibe, Jeng Yie Chan, Mohammed Bensellam, D....> ;Molecular Metabolism. 2018 Apr 1
• 41 citations
  Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
  Jeroen Overman, Frank Fontaine, Mehdi Moustaqil, Deepak Mittal, Emma Sierecki, Natalia Sacilotto, Johannes Zuegg, Avril A. B. Robertson, Kelly A. Holmes, Angela A. Sal...> ;Elife. 2017 Jan 31
• 25 citations
  Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity
  Johannes Zuegg, Craig Muldoon, George Adamson, Declan McKeveney, Giang Le Thanh, Rajaratnam Premraj, Bernd Becker, Mu Cheng, Alysha G. Elliott, Johnny X. Huang, Mark S...> ;Nature Communications. 2015 Jul 21
• 1709 citations
  A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
  Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah C. Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz,...> ;Nature Medicine. 2015 Feb 16
• 20 citations
  Screening strategies to identify new antibiotics.
  Mark S. Butler, Mark E. Cooper> ;Current Drug Targets. 2012 Feb 29
• 8 citations
  Identification of a Naturally Occurring Quinazolin-4(3H)-one Firefly Luciferase Inhibitor
  Brinda Somanadhan, Chungyan Leong, Stephen R. Whitton, Siewbee Ng, Antony D. Buss, Mark S. Butler> ;Journal of Natural Products. 2011 Jun 3
• 186 citations
  Antibiotics in the clinical pipeline in 2011.
  Mark S. Butler, Mark E. Cooper> ;The Journal of Antibiotics. 2011 Jun 1
• 12 citations
  Synthesis of essramycin and comparison of its antibacterial activity.
  Ernest H. L. Tee, Tomislav Karoli, Soumya Ramu, Johnny X. Huang, Mark S. Butler, Mark E. Cooper> ;Journal of Natural Products. 2010 Nov 4
• Natural products to drugs: natural product-derived compounds in clinical trials.
  Butler, M. S.> ;Nat Prod Rep. 2008 Jun
• 29 citations
  Mother Nature’s gifts to diseases of man: the impact of natural products on anti-infective, anticholestemics and anticancer drug discovery
  Mark S. Butler, David J. Newman> ;Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 2008 Jan 1
• 186 citations
  Natural products — The future scaffolds for novel antibiotics?
  Mark S. Butler, Antony D. Buss> ;Biochemical Pharmacology. 2006 Mar 30
• 7 citations
  Sundaicumones A and B, Polyprenylated Acylphloroglucinol Derivatives from Calophyllum sundaicum with Weak Activity against the Glucocorticoid Receptor
  Shugeng Cao, Kia-Ngee Low, Robert P. Glover, Sharon C. Crasta, Siewbee Ng, and Antony D. Buss, Mark S. Butler> ;Journal of Natural Products. 2006 Feb 25
• 1 citations
  Pyrrole Carboxamidine Tryptase Inhibitors from Leptonychia pubescens
  Lay Kien Yang, Sok Peng Ng, Horst Flotow, K. Yoganathan, B. O. Daramola, Djaja D. Soejarto, Antony D. Buss, Mark S. Butler> ;Planta Medica. 2005 Nov 1
• 4 citations
  NMR spectral assignments of three aspidofractinine alkaloids, kopsine, fruticosine and fruticosamine
  Robert P. Glover, K. Yoganathan, Mark S. Butler> ;Magnetic Resonance in Chemistry. 2005 Jun 1
• Natural products to drugs: natural product derived compounds in clinical trials.
  Butler, M. S.> ;Nat Prod Rep. 2005 Apr
• 44 citations
  New estrogenic prenylflavone from Epimedium brevicornum inhibits the growth of breast cancer cells.
  Sook Peng Yap, Ping Shen, Mark S. Butler, Yinhan Gong, Chong Jin Loy, Eu Leong Yong> ;Planta Medica. 2005 Feb 1
• 606 citations
  The Role of Natural Product Chemistry in Drug Discovery
  Mark S. Butler> ;Journal of Natural Products. 2004 Nov 23
• 15 citations
  Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A-D, from Emericella aurantiob...
  K. Yoganathan, Christine Rossant, Robert P. Glover, Shugeng Cao, Jagadese J. Vittal, Siewbee Ng, Yicun Huang, and Antony D. Buss, Mark S. Butler> ;Journal of Natural Products. 2004 Oct 1
• 16 citations
  Cochlioquinones and epi-cochlioquinones: antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum.
  K. Yoganathan, Lay-Kien Yang, Christine Rossant, Yicun Huang, Siewbee Ng, Mark S. Butler, Antony D. Buss> ;The Journal of Antibiotics. 2004 Jan 25
• 9 citations
  Phenolic derivatives from Wigandia urens with weak activity against the chemokine receptor CCR5
  Shugeng Cao, Christine Rossant, Siewbee Ng, Antony D. Buss, Mark S. Butler> ;Phytochemistry. 2003 Nov 1
• 44 citations
  10-Methoxydihydrofuscin, Fuscinarin, and Fuscin, Novel Antagonists of the Human CCR5 Receptor from Oidiodendron griseum
  K. Yoganathan, Christine Rossant, Siewbee Ng, Yicun Huang, Mark S. Butler, Antony D. Buss> ;Journal of Natural Products. 2003 Jul 23
• 120 citations
  Identification of Chelerythrine as an Inhibitor of BclXL Function
  Shing Leng Chan, Mei Chin Lee, Kuan Onn Tan, Lay-Kien Yang, Alex S. Y. Lee, Horst Flotow, Nai Yang Fu, Mark S. Butler, Doel D. Soejarto, Antony D. Buss, Victor C. Yu> ;The Journal of Biological Chemistry. 2003 Jun 6
• 6 citations
  Flavonoids from Artocarpus lanceifolius.
  Shugeng Cao, Mark S. Butler, Antony D. Buss> ;Natural Product Research. 2003 Jan 1
• 7 citations
  Naturally occurring cembranes from an Australian sarcophyton species.
  Ngoc B. Pham, Mark S. Butler, Ronald J. Quinn> ;Journal of Natural Products. 2002 Jul 25
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