MarkCChamesMD

Obstetrics & Gynecology • Ann Arbor, MI

Maternal & Fetal Medicine/High Risk

Associate Professor, Obstetrics & Gynecology, University of Michigan Medical School

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Office
1500 East Medical Center Dr
9th Floor Recp B
Ann Arbor, MI 48109
Phone+1 734-763-6295
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Education & Training

University of Cincinnati Medical Center/College of MedicineFellowship, Maternal-Fetal Medicine, 2000 - 2003
Beaumont Health (Dearborn)Residency, Obstetrics and Gynecology, 1996 - 2000
Wayne State University School of MedicineClass of 1996

Certifications & Licensure

MI State Medical License 1998 - 2026
KY State Medical License 2003 - 2005
OH State Medical License 2000 - 2005
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Maternal-Fetal Medicine

Publications & Presentations

PubMed

Group B streptococcus induces cellular senescence in human amnion epithelial cells through a partial interleukin-1-mediated mechanism.
Hae-Ryung Park, Kelly A Hogan, Sean M Harris, Mark C Chames, Rita Loch-Caruso> ;Biology of Reproduction. 2024 Feb 10
11 citations
Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro.
Hae-Ryung Park, Sean M. Harris, Erica Boldenow, Richard C. McEachin, Maureen A. Sartor, Mark C. Chames, Rita Loch-Caruso> ;Biology of Reproduction. 2018 Mar 1
28 citations
Restless Legs Syndrome and Sleep-Wake Disturbances in Pregnancy.
Galit Levi Dunietz, Lynda D. Lisabeth, Kerby Shedden, Q Afifa Shamim-Uzzaman, Alexandra S. Bullough, Mark C. Chames, Marc F Bowden, Louise M. O'Brien> ;Journal of Clinical Sleep Medicine. 2017 Jul 15
11 citations
The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro.
Erica Boldenow, Iman Hassan, Mark C. Chames, Chuanwu Xi, Rita Loch-Caruso> ;Reproductive Toxicology. 2015 Apr 1
22 citations
Role of cytokine signaling in group B Streptococcus-stimulated expression of human beta defensin-2 in human extraplacental membranes.
Erica Boldenow, Kelly A. Hogan, Mark C. Chames, David M. Aronoff, Chuanwu Xi, Rita Loch-Caruso> ;American Journal of Reproductive Immunology. 2015 Mar 1
55 citations
Hypertension, snoring, and obstructive sleep apnoea during pregnancy: a cohort study
Louise M. O'Brien, Alexandra S. Bullough, Mark C. Chames, Anita V. Shelgikar, Roseanne Armitage, Christian Guilleminualt, Colin E. Sullivan, Timothy R.B. Johnson, Rona...> ;BJOG. 2014 Dec 1
12 citations
Identifying post-partum diabetes after gestational diabetes mellitus: the right test
Catherine Kim, Mark C. Chames, Timothy R.B. Johnson> ;The Lancet. Diabetes & Endocrinology. 2013 Oct 1
67 citations
Snoring during pregnancy and delivery outcomes: a cohort study.
Louise M. O'Brien, Alexandra S. Bullough, Jocelynn T. Owusu, Kimberley A. Tremblay, Cynthia A. Brincat, Mark C. Chames, John D. Kalbfleisch, Ronald D. Chervin> ;Sleep. 2013 Nov 1
41 citations
Myomectomy during cesarean delivery
Dianrong Song, Wei Zhang, Mark C. Chames, Jie Guo> ;International Journal of Gynaecology and Obstetrics. 2013 Jun 1
34 citations
Antimicrobial peptide response to Group B Streptococcus in human extraplacental membranes in culture
Erica Boldenow, Sarah Jones, Richard W. Lieberman, Mark C. Chames, David M. Aronoff, Chuanwu Xi, Rita Loch-Caruso> ;Placenta. 2013 Jun 1
104 citations
Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study.
Louise M. O'Brien, Alexandra S. Bullough, Jocelynn T. Owusu, Kimberley A. Tremblay, Cynthia A. Brincat, Mark C. Chames, John D. Kalbfleisch, Ronald D. Chervin> ;American Journal of Obstetrics and Gynecology. 2012 Dec 1
85 citations
Validation of Watch-PAT-200 Against Polysomnography During Pregnancy
Louise M. O'Brien, Alexandra S. Bullough, Anita V. Shelgikar, Mark C. Chames, Roseanne Armitage, Ronald D. Chervin> ;Journal of Clinical Sleep Medicine. 2012 Jun 15
9 citations
Tissue-Specific Induction of COX-2 and Prostaglandins in Lipopolysaccharide-Stimulated Extraplacental Human Gestational Membranes in a 2-Chamber Transwell Culture System
Natalie W. Thiex, Mark C. Chames, Rita Loch-Caruso> ;Reproductive Sciences. 2010 Sep 22
13 citations
National survey of obstetrician attitudes about timing the subsequent pregnancy after perinatal death.
Katherine J. Gold, Irving G. Leon, Mark C. Chames> ;American Journal of Obstetrics and Gynecology. 2010 Apr 1
30 citations
Tissue-specific cytokine release from human extra-placental membranes stimulated by lipopolysaccharide in a two-compartment tissue culture system
Natalie W. Thiex, Mark C. Chames, Rita Loch-Caruso> ;Reproductive Biology and Endocrinology. 2009 Oct 26
13 citations
Giant Pulmonary Sequestration: The Rare Case Requiring the EXIT Procedure with Resection and ECMO
George B. Mychaliska, Benjamin S. Bryner, Clark Nugent, John D.E. Barks, Ronald B. Hirschl, Kimberly McCrudden, Mark C. Chames, Carlen Gomez-Fifer, Monica N. Servin, S...> ;Fetal Diagnosis and Therapy. 2009 Aug 1
35 citations
Trauma During Pregnancy : Outcomes and Clinical Management
Mark C. Chames, Mark D. Pearlman> ;Clinical Obstetrics and Gynecology. 2008 Jun 1
42 citations
Preventive counseling among women with histories of gestational diabetes mellitus.
Catherine Kim, Laura N. McEwen, Eve A. Kerr, John D. Piette, Mark C. Chames, Assiamira Ferrara, William H. Herman> ;Diabetes Care. 2007 Oct 1
42 citations
Risk factors for the breakdown of perineal laceration repair after vaginal delivery.
Meredith K. Williams, Mark C. Chames> ;American Journal of Obstetrics and Gynecology. 2006 Sep 1
8 citations
Determination of non-bilayer phospholipid arrangements and their antibodies in placentae and sera of patients with hypertensive disorders of pregnancy
Begoña Campos, Mark C. Chames, J. M. Lantry, J. P. Bill, Annie Eis, Diane E. Brockman, J. Neil, E. Tischner, J. Barton, Carlos Wong, S. Schwemberger, J. Cornelius, Les...> ;Placenta. 2006 Feb 1
40 citations
Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes
Howard G. Shertzer, Corey D. Clay, Mary Beth Genter, Mark C. Chames, Scott N. Schneider, Greg G. Oakley, Daniel W. Nebert, Timothy P. Dalton> ;Free Radical Biology & Medicine. 2004 Mar 1
59 citations
Subsequent pregnancy outcome in women with a history of HELLP syndrome at ≤ 28 weeks of gestation
Mark C. Chames, Bassam Haddad, Jeffrey Livingston, Baha M. Sibai, John R. Barton> ;American Journal of Obstetrics and Gynecology. 2003 Jun 1
22 citations
Spontaneous preterm delivery in the type 1 diabetic pregnancy: The role of glycemic control
Oormila Kovilam, Jane Khoury, Menachem Miodovnik, Mark C. Chames, Joseph A. Spinnato, Bahaeddine M Sibai> ;The Journal of Maternal-Fetal & Neonatal Medicine. 2002 Apr 1
115 citations
Late postpartum eclampsia: A preventable disease?
Mark C. Chames, Jeffrey C. Livingston, Thomas S. Ivester, Bahaeddine M Sibai, John R. Barton> ;American Journal of Obstetrics and Gynecology. 2002 Jun 1
Anisocoria: a rare consequence of endoscopic sinus surgery.
Kosko, J. R., Pratt, M. F., Chames, M., Letterman, I.> ;Otolaryngol Head Neck Surg. 1998 Feb
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