MarkZChenMD

PubMed

• 35 citations
  Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal
  Valeria Yartseva, Leonard D. Goldstein, Julia Rodman, Lance Kates, Mark Z. Chen, Ying-Jiun J. Chen, Oded Foreman, Christian W. Siebel, Zora Modrusan, Andrew S. Peterso...> ;Cell Reports. 2020 Feb 4
• 8 citations
  Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy.
  Joshua C. Chang, Steffen Durinck, Mark Z. Chen, Nadia Martinez-Martin, Jingli A. Zhang, Isabelle Lehoux, Hong Li, May Lin, Jiansheng Wu, Travis W. Bainbridge, James A....> ;Scientific Reports. 2019 Jun 20
• A pharmacology guided approach for setting limits on product-related impurities for bispecific antibody manufacturing.
  Sharmila Rajan, Junichiro Sonoda, Timothy Tully, Ambrose Williams, Feng Yang, Frank Macchi, Terry Hudson, Mark Z. Chen, Shannon Liu, Nicole Valle, Kyra J. Cowan, Thoma...> ;Journal of Pharmacological and Toxicological Methods. 2018 Nov 1
• 37 citations
  FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.
  Mark Z. Chen, Joshua C. Chang, Jose Zavala-Solorio, Lance Kates, Minh Thai, Annie Ogasawara, Xiaobo Bai, Sean Flanagan, Victor Nunez, Khanhky Phamluong, James Ziai, Ro...> ;Molecular Metabolism. 2017 Nov 1
• Erratum to: Training guidelines for endovascular stroke intervention: an international multi-society consensus document.
  Lavine, S. D.,Cockroft, K.,Hoh, B.,Bambakidis, N.,Khalessi, A. A.,Woo, H.,Riina, H.,Siddiqui, A.,Hirsch, J. A.,Chong, W.,Rice, H.,Wenderoth, J.,Mitchell, P.,Coulthard,...> ;Neuroradiology. 2017 Jun 22
• 74 citations
  FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases.
  Junichiro Sonoda, Mark Z. Chen, Amos Baruch> ;Hormone Molecular Biology and Clinical Investigation. 2017 May 19
• 79 citations
  Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.
  Ganesh Kolumam, Mark Z. Chen, Raymond K. Tong, Jose Zavala-Solorio, Lance Kates, Nicholas van Bruggen, Jed Ross, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Cara...> ;Ebiomedicine. 2015 Jul 1
• 35 citations
  Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis
  Milos Lazic, Maria Eugenia Inzaugarat, Davide Povero, Iris C. Zhao, Mark Chen, Madlena Nalbandian, Yury I. Miller, Alejandra C. Cherñavsky, Ariel E. Feldstein, Dorothy...> ;Plos One. 2014 Sep 24
• 34 citations
  EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS.
  Claire E. Le Pichon, Sara L. Dominguez, Hilda Solanoy, Hai Ngu, Nicholas Lewin-Koh, Mark Z. Chen, Jeffrey Eastham-Anderson, Ryan J. Watts, Kimberly Scearce-Levie> ;Plos One. 2013 Apr 26
• 55 citations
  Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.
  Ai-Luen Wu, Bo Feng, Mark Z. Chen, Ganesh Kolumam, Jose Zavala-Solorio, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Carano, Junichiro Sonoda> ;Plos One. 2013 Feb 22
• 30 citations
  Spatially Coordinated Kinase Signaling Regulates Local Axon Degeneration
  Mark Z. Chen, Janice A. Maloney, Dara Y. Kallop, Jasvinder Atwal, Stephen J. Tam, Kristin Baer, Holger Kissel, Joshua S. Kaminker, Joseph W. Lewcock, Robby M. Weimer, ...> ;The Journal of Neuroscience. 2012 Sep 26
• 208 citations
  An Effector-Reduced Anti-β-Amyloid (Aβ) Antibody with Unique Aβ Binding Properties Promotes Neuroprotection and Glial Engulfment of Aβ
  Oskar Adolfsson, Maria Pihlgren, Nicolas Toni, Yvan Varisco, Anna Lucia Buccarello, Katia Antoniello, Sophie Lohmann, Kasia Piorkowska, Valerie Gafner, Jasvinder Atwal...> ;The Journal of Neuroscience. 2012 Jul 11
• 145 citations
  Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
  Simon Schenk, Carrie E. McCurdy, Andrew Philp, Mark Z. Chen, Michael J. Holliday, Gautum K. Bandyopadhyay, Olivia Osborn, Keith Baar, Jerrold M. Olefsky> ;The Journal of Clinical Investigation. 2011 Nov 1
• 152 citations
  DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity
  Arundhati Sengupta Ghosh, Bei Wang, Christine Pozniak, Mark Z. Chen, Ryan J. Watts, Joseph W. Lewcock> ;The Journal of Cell Biology. 2011 Sep 5
• 166 citations
  Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport
  Kazuaki Ohtsubo, Mark Z. Chen, Jerrold M. Olefsky, Jamey D. Marth> ;Nature Medicine. 2011 Sep 1
• 18 citations
  Oxidative Stress Decreases Phosphatidylinositol 4,5-Bisphosphate Levels by Deactivating Phosphatidylinositol- 4-phosphate 5-Kinase β in a Syk-dependent Manner
  Mark Z. Chen, Xiaohui Zhu, Hui Qiao Sun, Yuntao S. Mao, Yongjie Wei, Masaya Yamamoto, Helen L. Yin> ;The Journal of Biological Chemistry. 2009 Aug 28
• 41 citations
  Hypertonic Stress Increases Phosphatidylinositol 4,5-Bisphosphate Levels by Activating PIP5KIβ
  Masaya Yamamoto, Mark Z. Chen, Ying-Jie Wang, Hui Qiao Sun, Yongjie Wei, Manuel Martinez, Helen L. Yin> ;The Journal of Biological Chemistry. 2006 Oct 27
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