MarkJefferyCowanMD

Pulmonology • Baltimore, MD

Critical Care Medicine, Pleural Disease

Assistant Professor, Medicine, University of Maryland School of Medicine

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Office
10 N Greene St Rm 3d122
Baltimore, MD 21201
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Education & Training

National Institutes of Health Clinical CenterFellowship, Critical Care Medicine (Internal Medicine), 1993 - 1997
University of Michigan Health SystemFellowship, Pulmonary Disease and Critical Care Medicine, 1994 - 1995
George Washington UniversityResidency, Internal Medicine, 1989 - 1993
University of Colorado School of Medicine Anschutz Medical CampusClass of 1989

Certifications & Licensure

MD State Medical License 1996 - 2024
FL State Medical License 2018 - 2020
DE State Medical License 2006 - 2015
DC State Medical License 1990 - 2004
MI State Medical License 1994 - 1998

Publications & Presentations

PubMed

2 citations
Lung Cancer Screening in Patients with COPD—A Case Report
Roxana Amirahmadi, Avnee Kumar, Mark J. Cowan, Janaki Deepak> ;Medicina. 2019 Jul 11
11 citations
Activation of heat shock response augments fibroblast growth factor-1 expression in wounded lung epithelium
Rachel Greenberg Scheraga, Christopher R. Thompson, Mohan E. Tulapurkar, Ashish Nagarsekar, Mark J. Cowan, Ratnakar Potla, Junfeng Sun, Rongman Cai, Carolea Logun, Jam...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2016 Nov 1
6 citations
A 32-Year-Old Female with AIDS, Pneumocystis jiroveci Pneumonia, and Methemoglobinemia
Guillermo J. Giangreco, Dean Campbell, Mark J. Cowan> ;Case Reports in Critical Care. 2013 Jun 27
8 citations
Septicemia and Aortic Valve Endocarditis due to Erysipelothrix rhusiopathiae in a Homeless Man
Dean Campbell, Mark J. Cowan> ;Case Reports in Infectious Diseases. 2013 Apr 10
6 citations
Nonpharmacologic approach to minimizing shivering during surface cooling: a proof of principle study.
Nirav Shah, Mark J. Cowan, Edward M. Pickering, Houtan Sareh, Majid Afshar, Dawn Fox, Jennifer Marron, Jennifer Davis, Keith E. Herold, Carl B. Shanholtz, Jeffrey D. H...> ;Journal of Critical Care. 2012 Dec 1
6 citations
Prostaglandin E2 potentiates heat shock-induced heat shock protein 72 expression in A549 cells
Nirav Shah, Mohan E. Tulapurkar, Ishwar S. Singh, James H. Shelhamer, Mark J. Cowan, Jeffrey D. Hasday> ;Prostaglandins & Other Lipid Mediators. 2010 Sep 1
140 citations
The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis
Jessica L. Miller, Kamalakannan Velmurugan, Mark J. Cowan, Volker Briken> ;Plos Pathogens. 2010 Apr 22
22 citations
Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS.
Larry A. Sonna, Lauren Hawkins, Matthew Lissauer, Pam Maldeis, Michael Towns, Steven B. Johnson, Richard D. Moore, Ishwar S. Singh, Mark J. Cowan, Jeffrey D. Hasday> ;Cell Stress & Chaperones. 2010 Jan 1
137 citations
Tobacco Smoking Inhibits Expression of Proinflammatory Cytokines and Activation of IL-1R-Associated Kinase, p38, and NF-κB in Alveolar Macrophages Stimulated with TLR2...
Haiyan Chen, Mark J. Cowan, Jeffrey D. Hasday, Stefanie N. Vogel, Andrei E. Medvedev> ;Journal of Immunology. 2007 Nov 1
6 citations
Severe Metabolic Alkalosis due to Pyloric Obstruction: Case Presentation, Evaluation, and Management
Meredith Mccauley, Manjula Gunawardane, Mark J. Cowan> ;The American Journal of the Medical Sciences. 2006 Dec 1
10 citations
Polyamine-mediated reduction in human airway epithelial migration in response to wounding is PGE2 dependent through decreases in COX-2 and cPLA2 protein levels
Mark J. Cowan, Timothy Coll, James H. Shelhamer> ;Journal of Applied Physiology. 2006 Oct 1
11 citations
The role of TFIID, the initiator element and a novel 5′ TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-α promoter
Mark J. Cowan, Xianglan Yao, Rafał Pawliczak, Xiu-li Huang, Carolea Logun, Patricia Madara, Sura Alsaaty, Tong Wu, James H. Shelhamer> ;Biochimica Et Biophysica Acta. 2004 Nov 5
12 citations
Characterization of the human p11 promoter sequence.
Xiu-li Huang, Rafał Pawliczak, Xianglan Yao, Patricia Madara, Sura Alsaaty, James H. Shelhamer, Mark J. Cowan> ;Gene. 2003 May 22
20 citations
Interferon-γ Induces p11 Gene and Protein Expression in Human Epithelial Cells through Interferon-γ-activated Sequences in the p11Promoter
Xiu-li Huang, Rafał Pawliczak, Xianglan Yao, Mark J. Cowan, Mark T. Gladwin, Michael J. Walter, Michael J. Holtzman, Patricia Madara, Carolea Logun, James H. Shelhamer> ;The Journal of Biological Chemistry. 2003 Mar 14
19 citations
Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells.
Xiu-li Huang, Rafał Pawliczak, Mark J. Cowan, Mark T. Gladwin, Patricia Madara, Carolea Logun, James H. Shelhamer> ;The Journal of Biological Chemistry. 2002 Oct 11
45 citations
CT Virtual Bronchoscopy of the Central Airways in Patients With Wegener's Granulomatosis
Ronald M. Summers, Neil R. Aggarwal, Michael C. Sneller, Mark J. Cowan, Bradford J. Wood, Carol A. Langford, James H. Shelhamer> ;Chest. 2002 Jan 1
22 citations
OXIDANT-INDUCED CELL DEATH IN RESPIRATORY EPITHELIAL CELLS IS DUE TO DNA DAMAGE AND LOSS OF ATP
Uday B. Nanavaty, Rafał Pawliczak, Jeremy Doniger, Mark T. Gladwin, Mark J. Cowan, Carolea Logun, James H. Shelhamer> ;Experimental Lung Research. 2002 Jan 1
22 citations
p11 Expression in Human Bronchial Epithelial Cells Is Increased by Nitric Oxide in a cGMP-dependent Pathway Involving Protein Kinase G Activation
Rafał Pawliczak, Mark J. Cowan, Xiulie Huang, Uday B. Nanavaty, Sura Alsaaty, Carolea Logun, James H. Shelhamer> ;The Journal of Biological Chemistry. 2001 Nov 30
45 citations
Disorders of Ciliary Motility
Mark J. Cowan, Mark T. Gladwin, James H. Shelhamer> ;The American Journal of the Medical Sciences. 2001 Jan 1
14 citations
Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism
Mark T. Gladwin, Xianglan Yao, Morton J. Cowan, Xiulie Huang, R. Schneider, L. R. Grant, Carolea Logun, James H. Shelhamer> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2000 Dec 1
8 citations
Respiratory response during arm elevation in isolated diaphragm weakness
Fernando J. Martinez, Robert L. Strawderman, Kevin R. Flaherty, Mark Cowan, Jonathan B. Orens, John J. Wald> ;American Journal of Respiratory and Critical Care Medicine. 1999 Aug 1
75 citations
Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity.
Xianglan Yao, Morton J. Cowan, Mark T. Gladwin, Lawrence Mm, C. W. Angus, James H. Shelhamer> ;The Journal of Biological Chemistry. 1999 Jun 11
40 citations
Tumor Necrosis Factor- α Stimulates Human Clara Cell Secretory Protein Production by Human Airway Epithelial Cells
Xianglan Yao, Stewart J. Levine, M. J. Cowan, Carolea Logun, James H. Shelhamer> ;American Journal of Respiratory Cell and Molecular Biology. 1998 Oct 1
24 citations
Interferon-γ stimulates human Clara cell secretory protein production by human airway epithelial cells
Xianglan Yao, T. Ikezono, Morton J. Cowan, Carolea Logun, C. W. Angus, James H. Shelhamer> ;The American Journal of Physiology. 1998 May 1
15 citations
Antisense inhibition of 85-kDa cPLA2 blocks arachidonic acid release from airway epithelial cells.
Tai Te Wu, Stewart J. Levine, Morton J. Cowan, Carolea Logun, C. W. Angus, James H. Shelhamer> ;The American Journal of Physiology. 1997 Aug 1
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Hospital Affiliations

Atlantic General HospitalBerlin, Maryland
University of Maryland Medical Center Midtown CampusBaltimore, Maryland
Veterans Affairs Maryland Health Care System-Baltimore DivisionBaltimore, Maryland