Mark T Dransfield MD

Pulmonology•Birmingham, AL

Critical Care Medicine

Professor, Medicine, University of Alabama School of Medicine

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2000 6th Ave SBirmingham, AL 35233
Phone+1 205-934-9999
Fax+1 205-975-5666

Summary

Medical Director, UAB Lung Health Center

Education & Training

University of Alabama Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 2000 - 2003
University of Alabama Medical CenterResidency, Internal Medicine, 1997 - 2000
University of North Carolina at Chapel Hill School of MedicineClass of 1997

Certifications & Licensure

AL State Medical License 1998 - 2025
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012

Clinical Trials

US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study Start of enrollment: 2007 Feb 01
Completed
Phase 2
Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study Start of enrollment: 2008 Feb 01
Completed
Phase 2
Long-term Oxygen Treatment Trial Start of enrollment: 2009 Jan 01
Completed
Phase 3
Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema Start of enrollment: 2009 Mar 01
Terminated
Phase 2
Simvastatin Therapy for Moderate and Severe COPD Start of enrollment: 2010 Mar 01
Terminated
Phase 3
Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA) Start of enrollment: 2010 Nov 01
Completed
Phase 2
Symbicort in Airway Predominant Chronic Obstructive Pulmonary Disease (COPD) Start of enrollment: 2012 Apr 01
Completed
Phase 4
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Start of enrollment: 2012 Oct 01
Terminated
Not Applicable
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study) Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Study of COPD Subgroups and Biomarkers
ACTIVE_NOT_RECRUITING
TOPIC Trial for COPD Start of enrollment: 2015 May 01
Completed
Early Phase 1
Evaluation of COPD Co-Pilot Start of enrollment: 2016 Oct 01
Unknown status
The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor Start of enrollment: 2017 Mar 16
COMPLETED
PHASE2
Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency Start of enrollment: 2019 Apr 08
COMPLETED
PHASE2
The Multicenter Topic Trial Start of enrollment: 2021 Dec 01
Withdrawn
Phase 2
COVID-19 Study of Safety and Tolerability of Alvelestat Start of enrollment: 2021 Jan 25
Completed
Phase 1, Phase 2
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI Start of enrollment: 2020 Jun 28
COMPLETED
SPIROMICS Study of Early COPD Progression (SOURCE) Start of enrollment: 2021 Sep 08
RECRUITING
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Publications & Presentations

PubMed

Improving Research for COPD in Rural Areas: A Statement from the COPD Foundation Medical and Scientific Advisory Committee.
Maura E Thornton, David M Mannino, Jill A Ohar, Nirupama Putcha, Paul F Simonelli
Chronic Obstructive Pulmonary Diseases. 2025-09-29
Two randomized controlled Phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency.
J Michael Wells, Ingrid L Titlestad, Hanan Tanash, Alice M Turner, Kenneth R Chapman
The European Respiratory Journal. 2025-09-18
Neutrophil-to-Lymphocyte Ratio (NLR) as a Biomarker in Clinically Stable Chronic Obstructive Pulmonary Disease: SPIROMICS cohort.
Daniel T Hoesterey, Hong Dang, Daniela Markovic, Russell G Buhr, Donald P Tashkin
Annals of the American Thoracic Society. 2025-09-08

Journal Articles

Association of Dysanapsis with Chronic Obstructive Pulmonary Disease Among Older Adults
Alain Bertoni, Gerard Criner, Mark T Dransfield, Meilan K Han, Nadia N Hansel, Erin D Michos, Elizabeth C Oelsner, Karol E Watson, JAMA

Authored Content

Association of Dysanapsis with Chronic Obstructive Pulmonary Disease Among Older AdultsJune 2020

Press Mentions

Warriner Named 2025 Brewer-Heslin Award WinnerAugust 19th, 2025
Ananda and Rita Basu Celebrated at Spring 2025 Endowed Chairs and Professorships ReceptionMay 14th, 2025
Another Biologic Reduces COPD ExacerbationsApril 30th, 2025
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