MarkGregoryGarzottoMD

Urology • Portland, OR

Professor, Urology and Radiation Oncology, OHSU, Chief of Urology, Portland VA Medical Center

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Office
3181 SW Sam Jackson Park Rd
Portland, OR 97239
Phone+1 503-494-4779

Fax+1 503-346-1501
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Urologic Surgical Oncology, 1995 - 1999
University of FloridaResidency, Urology, 1992 - 1995
University of FloridaResidency, Surgery, 1990 - 1992
Louisiana State University School of Medicine in New OrleansClass of 1990

Certifications & Licensure

OR State Medical License 2000 - 2025
NY State Medical License 1995 - 2000
FL State Medical License 1992 - 1998
LA State Medical License 1990 - 1990
American Board of Urology Urology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

Chemotherapy After Prostatectomy (CAP) For High Risk Prostate Carcinoma Start of enrollment: 2006 Jun 01
Completed
Phase 3
S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone Therapy Start of enrollment: 2006 Aug 01
Completed
Phase 3
Radiation Therapy and Docetaxel in Treating Patients Who Are Undergoing Surgery for Localized Prostate Cancer Start of enrollment: 2006 Jan 31
Active, not recruiting
Phase 1, Phase 2
Statin Therapy Versus Placebo Prior to Prostatectomy Start of enrollment: 2007 Dec 01
Completed
Not Applicable
Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA Methylation Start of enrollment: 2011 Jul 01
Completed
Not Applicable
Magnetic Resonance Spectroscopic Imaging Study of Prostatic Fats to Distinguish the Difference Between High and Low Risk Prostate Cancer Start of enrollment: 2013 Jan 01
Completed
Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer Start of enrollment: 2018 Dec 03
Recruiting
Phase 2
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Publications & Presentations

PubMed

BMI and BPH correlate with urinary microbiome diversity and lower urinary tract symptoms in men.
Bowie, K., Karstens, L., Garzotto, M., Orwoll, E.> ;Biorxiv. 2023 Dec 15
3 citations
Androgen Deprivation and Radiotherapy with or Without Docetaxel for Localized High-risk Prostate Cancer: Long-term Follow-up from the Randomized NRG Oncology RTOG 0521...
Oliver Sartor, Theodore G Karrison, Howard M Sandler, Leonard G Gomella, Mahul B Amin, James Purdy, Jeff M Michalski, Mark G Garzotto, Nadeem Pervez, Alexander G Balog...> ;European Urology. 2023 Aug 1
1 citations
The Influence of the Pretreatment Immune State on Response to Radiation Therapy in High-Risk Prostate Cancer: A Validation Study From NRG/RTOG 0521.
William A Hall, Theodore G Karrison, Seth A Rosenthal, Mahul B Amin, Leonard G Gomella, James A Purdy, A Oliver Sartor, Jeff M Michalski, Mark G Garzotto, Carmen Bergo...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Oct 1
2 citations
Metabolic activity diffusion imaging (MADI): II. Noninvasive, high-resolution human brain mapping of sodium pump flux and cell metrics.
Charles S Springer Jr, Eric M Baker, Xin Li, Brendan Moloney, Martin M Pike, Gregory J Wilson, Valerie C Anderson, Manoj K Sammi, Mark G Garzotto, Ryan P Kopp, Fergus ...> ;NMR in Biomedicine. 2023 Jan 1
Calibrated Regression Models Based on the Risk of Clinical Nodal Metastasis Should be Used as Decision Aids for Prostate Cancer Staging to Reduce Unnecessary Imaging.
Mitchell Hayes, Yun Yu, Solange Bassale, Nicholas Chakiryan, Yiyi Chen, Shangyuan Ye, Mark Garzotto, Ryan Kopp> ;Clinical Genitourinary Cancer. 2022 Dec 1
Editorial Comment.
Poone S Shoureshi, Mark Garzotto> ;The Journal of Urology. 2021 Jun 1
Editorial Commentary.
Sean T Hua, Mark Garzotto> ;Urology Practice. 2021 May 1
EDITORIAL COMMENT.
Sean T Hua, Mark Garzotto> ;Urology. 2020 Nov 1
14 citations
Veterans Affairs Cooperative Studies Program Study #553: Chemotherapy After Prostatectomy for High-risk Prostate Carcinoma: A Phase III Randomized Study.
Daniel W. Lin, Mei Chiung Shih, William J. Aronson, Joseph W. Basler, Tomasz M. Beer, Mary Brophy, Matthew R. Cooperberg, Mark Garzotto, W. Kevin Kelly, Kelvin K. Lee,...> ;European Urology. 2020 May 1
15 citations
Phytol and its metabolites phytanic and pristanic acids for risk of cancer: current evidence and future directions
Gerd Bobe, Zhenzhen Zhang, Ryan Kopp, Mark Garzotto, Jackilen Shannon, Yumie Takata> ;European Journal of Cancer Prevention. 2020 Mar 1
37 citations
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.
Zhenzhen Zhang, Mark Garzotto, Edward W. Davis, Motomi Mori, Wesley Stoller, Paige E. Farris, Carmen P. Wong, Laura M. Beaver, George Thomas, David E. Williams, Roderi...> ;Nutrition and Cancer. 2020 Jan 2
10 citations
Polymorphisms in oxidative stress pathway genes and prostate cancer risk
Zhenzhen Zhang, Duo Jiang, Chi Wang, Mark Garzotto, Ryan Kopp, Beth Wilmot, Philippe Thuillier, Andy Dang, Amy Palma, Paige E. Farris, Jackilen Shannon> ;Cancer Causes & Control. 2019 Oct 30
3 citations
Dairy Product Consumption and Prostate Cancer Risk in the United States
Isabella Preble, Zhenzhen Zhang, Ryan Kopp, Mark Garzotto, Gerd Bobe, Jackilen Shannon, Yumie Takata> ;Nutrients. 2019 Jul 16
2 citations
The estimated prevalence of missed positive lymph nodes based on extent of lymphadenectomy at radical prostatectomy.
Nicholas H. Chakiryan, Ann Martinez Acevedo, Michael J. Conlin, Mark Garzotto, Yiyi Chen, Jen-Jane Liu, Christopher L. Amling, Ryan Kopp> ;Urologic Oncology. 2019 Jul 8
14 citations
Optimizing the Sequence of Chemotherapy for Upper Tract Urothelial Carcinoma with Clinically Positive Regional Lymph Nodes.
Nicholas H. Chakiryan, Ann Martinez, Lina Gao, Jen-Jane Liu, Christopher L. Amling, Mark Garzotto, Ryan Kopp> ;The Journal of Urology. 2019 Jun 7
84 citations
Effect of Chemotherapy With Docetaxel With Androgen Suppression and Radiotherapy for Localized High-Risk Prostate Cancer: The Randomized Phase III NRG Oncology RTOG 05...
Seth A. Rosenthal, Chen Hu, Oliver Sartor, Leonard G. Gomella, Mahul B. Amin, James A. Purdy, Jeff M. Michalski, Mark Garzotto, Nadeem Pervez, Alexander Balogh, George...> ;Journal of Clinical Oncology. 2019 Mar 12
6 citations
Endorectal MR imaging of prostate cancer: Evaluation of tumor capsular contact length as a sign of extracapsular extension.
Gustavo Mendez, Bryan R. Foster, Xin Li, Jackilen Shannon, Mark Garzotto, Christopher L. Amling, Fergus V. Coakley> ;Clinical Imaging. 2018 Jul 1
2 citations
Unconventional Bladder Preservation: Factors Predicting Failure to Receive Definitive Surgery following Chemotherapy for Nonmetastatic Muscle Invasive Bladder Cancer i...
Akash Kapadia, Ann Martinez Acevedo, Jen-Jane Liu, Mark Garzotto, Michael J. Conlin, Christopher L. Amling, Ryan Kopp> ;The Journal of Urology. 2018 Sep 1
4 citations
Bone turnover biomarkers identify unique prognostic risk groups in men with castration resistant prostate cancer and skeletal metastases: Results from SWOG S0421.
Primo N. Lara, Melissa Plets, Catherine M. Tangen, E. Gertz, Nicholas J. Vogelzang, Maha Hussain, Przemyslaw Twardowski, Mark Garzotto, J. P. Monk, Michael A. Carducci...> ;Cancer Treatment and Research Communications. 2018 Jan 1
9 citations
Improving risk stratification among veterans diagnosed with prostate cancer: impact of the 17-gene prostate score assay.
Julie Lynch, Megan P. Rothney, Raoul Salup, Cesar E. Ercole, Sharad C. Mathur, David A. Duchene, Joseph W. Basler, Javier Hernandez, Michael A. Liss, Michael P. Porter...> ;The American Journal of Managed Care. 2018 Jan 1
22 citations
Cyclooxygenase‐2 (COX‐2) inhibition for prostate cancer chemoprevention: double‐blind randomised study of pre‐prostatectomy celecoxib or placebo
Jason F. Flamiatos, Tomasz M. Beer, Julie N. Graff, Kristine M. Eilers, Wei Tian, Harman Sekhon, Mark Garzotto> ;BJU International. 2017 May 1
1 citations
Is Low-Risk Prostate Cancer More Indolent in Younger Patients?
Mark Garzotto> ;Journal of Clinical Oncology. 2017 Mar 27
9 citations
Docetaxel and mitoxantrone before radical prostatectomy in men with high-risk prostate cancer: 10-year follow-up and immune correlates.
Colin P. Bergstrom, Brian Ruffell, Christine M.T. Ho, Celestia S. Higano, William J. Ellis, Mark Garzotto, Tomasz M. Beer, Julie N. Graff> ;Anti-Cancer Drugs. 2017 Jan 1
17 citations
Effects of ω-3 Fatty Acids and Catechins on Fatty Acid Synthase in the Prostate: A Randomized Controlled Trial.
Zhenzhen Zhang, Mark Garzotto, Tomasz M. Beer, Philippe Thuillier, Stephen Lieberman, Motomi Mori, Wesley Stoller, Paige E. Farris, Jackilen Shannon> ;Nutrition and Cancer. 2016 Sep 20
32 citations
Relative sensitivities of DCE-MRI pharmacokinetic parameters to arterial input function (AIF) scaling
Xin Li, Yu Cai, Brendan Moloney, Yiyi Chen, Wei Huang, Mark Woods, Fergus V. Coakley, William D. Rooney, Mark Garzotto, Charles S. Springer> ;Journal of Magnetic Resonance. 2016 Aug 1
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Press Mentions

Extended LND During Radical Cystectomy Offers No Overall Survival EdgeApril 7th, 2023
EPO No Help for Erectile Dysfunction After Radical ProstatectomyJune 3rd, 2021
Aggressive Therapy Warranted for Gleason 10 Prostate CancerJuly 20th, 2018
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Grant Support

P-2: The Effect Of RAD On Androgen Receptor Expression And Activity In ProstateNational Cancer Institute2010–2011
The Effect Of Radiation On Androgen Receptor Expression And Activity In ProstateNational Cancer Institute2007–2009