MarkWJacksonMD

PubMed

• The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer.
  Doherty, M. R.,Parvani, J. G.,Tamagno, I.,Junk, D. J.,Bryson, B. L.,Cheon, H. J.,Stark, G. R.,Jackson, M. W.> ;Breast Cancer Res.. 2019 May 01
• Using interferon-beta to combat cancer stem cell properties in triple negative breast cancer.
  Doherty, M. R.,Jackson, M. W.> ;Oncoscience. 2018 Jul 24
• Breaking the Oncostatin M Feed-Forward Loop to Suppress Metastasis and Therapy Failure†
  Mark Jackson, MD> ;The Journal of Pathology. 2018 Feb 24
• Targeting Pancreatic Cancer Cell Plasticity: The Latest in Therapeutics.
  Smigiel, J. M.,Parameswaran, N.,Jackson, M. W.> ;Cancers (Basel). 2018 Jan 11
• Interferon-Beta Represses Cancer Stem Cell Properties in Triple-Negative Breast Cancer
  Melinda L Telli, Shaveta Vinayak, James M Ford, Mark W Jackson> ;Proceedings of the National Academy of Sciences. 2017 Dec 13
• DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer.
  Merry, C. R.,Forrest, M. E.,Sabers, J. N.,Beard, L.,Gao, X. H.,Hatzoglou, M.,Jackson, M. W.,Wang, Z.,Markowitz, S. D.,Khalil, A. M.> ;Hum. Mol. Genet.. 2015 Aug 27
• Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.
  Garbe, J. C.,Vrba, L.,Sputova, K.,Fuchs, L.,Novak, P.,Brothman, A. R.,Jackson, M.,Chin, K.,LaBarge, M. A.,Watts, G.,Futscher, B. W.,Stampfer, M. R.> ;Cell Cycle. 2014 Dec 09
• ETV1 positively regulates transcription of tumor suppressor ARF.
  Zynda, E.,Jackson, M. W.,Bhattacharya, P.,Kandel, E. S.> ;Cancer Biol. Ther.. 2013 Oct 26
• IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage.
  Cheon, H.,Holvey-Bates, E. G.,Schoggins, J. W.,Forster, S.,Hertzog, P.,Imanaka, N.,Rice, C. M.,Jackson, M. W.,Junk, D. J.,Stark, G. R.> ;EMBO J.. 2013 Oct 16
• Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
  Cipriano, R.,Bryson, B. L.,Miskimen, K. L.,Bartel, C. A.,Hernandez-Sanchez, W.,Bruntz, R. C.,Scott, S. A.,Lindsley, C. W.,Brown, H. A.,Jackson, M. W.> ;Oncogene. 2013 Aug 5
• Immunization with 60 kD Ro peptide produces different stages of preclinical autoimmunity in a Sjögren's syndrome model among multiple strains of inbred mice.
  Kurien, B. T.,Dsouza, A.,Igoe, A.,Lee, Y. J.,Maier-Moore, J. S.,Gordon, T.,Jackson, M.,Scofield, R. H.> ;Clin. Exp. Immunol.. 2013 Jul
• FAM 83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.
  Cipriano, R.,Miskimen, K. L.,Bryson, B. L.,Foy, C. R.,Jackson, M. W.> ;Oncotarget. 2013 May
• Constitutive CCND1/CDK2 Activity Substitutes for p53 Loss, or MYC or Oncogenic RAS Expression in the Transformation of Human Mammary Epithelial Cells.
  Junk, D. J.,Cipriano, R.,Stampfer, M.,Jackson, M. W.> ;PLoS ONE. 2013
• Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms.
  Gupta, K.,Thakur, V. S.,Bhaskaran, N.,Nawab, A.,Babcook, M. A.,Jackson, M. W.,Gupta, S.> ;PLoS ONE. 2012
• c-MYC Functions as a Molecular Switch to Alter the Response of Human Mammary Epithelial Cells to Oncostatin M.
  Kan, C.E., Cipriano, R., Jackson, M.W.> ;Cancer Res. 2011 Nov 15
• Delineating oncogene/tumor suppressor interactions in human mammary epithelial cells.
  Cipriano, R., Jackson, M.W.> ;Cell Cycle. 2011 Aug 15
• TGF-{beta} signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells.
  Cipriano, R., Kan, C.E., Graham, J., Danielpour, D., Stampfer, M., Jackson, M.W.> ;Proc Natl Acad Sci U S A. 2011 May 24
• Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis.
  Cipriano, R., Patton, J.T., Mayo, L.D., Jackson, M.W.> ;Cell Cycle. 2010 Apr 1
• Restoration of p53 functions protects cells from concanavalin A-induced apoptosis.
  Amin, A.R., Thakur, V.S., Gupta, K., Jackson, M.W., Harada, H., Agarwal, M.K., Shin, D.M., Wald, D.N., Agarwal, M.L.> ;Mol Cancer Ther. 2010 Feb
• Canine angiostrongylosis: an emerging disease in Europe.
  Helm, J.R., Morgan, E.R., Jackson, M.W., Wotton, P., Bell, R.> ;J Vet Emerg Crit Care (San Antonio). 2010 Feb
• Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.
  Lu, T., Jackson, M.W., Wang, B., Yang, M., Chance, M.R., Miyagi, M., Gudkov, A.V., Stark, G.R.> ;Proc Natl Acad Sci U S A. 2010 Jan 5
• Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.
  De, S., Cipriano, R., Jackson, M.W., Stark, G.R.> ;Cancer Res. 2009-10-15
• Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.
  Lu, T., Jackson, M.W., Singhi, A.D., Kandel, E.S., Yang, M., Zhang, Y., Gudkov, A.V., Stark, G.R.> ;Proc Natl Acad Sci U S A. 2009-09-22
• The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.
  Gomez, J.A., Sun, W., Gama, V., Hajkova, D., Yoshida, T., Wu, Z., Miyagi, M., Pink, J.J., Jackson, M.W., Danielpour, D., Matsuyama, S.> ;Cancer Biol Ther. 2009-09-01
• DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.
  Hastak, K., Paul, R.K., Agarwal, M.K., Thakur, V.S., Amin, A.R., Agrawal, S., Sramkoski, R.M., Jacobberger, J.W., Jackson, M.W., Stark, G.R., Agarwal, M.L.> ;Proc Natl Acad Sci U S A. 2008 Apr 29
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