MarkWalterLaytonMD

Clinical Trials

• Cross-over Study to Investigate Retinal Function Following Administration of a Single Dose of AZD9056 Start of enrollment: 2008 Jun 01

  Completed

  Phase 1

• Mass Balance and Metabolic Profiling of [14C]AZD5672 in Healthy Male Volunteers Start of enrollment: 2008 Jun 01

  Completed

  Phase 1

• A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis Start of enrollment: 2008 Jul 01

  Completed

  Phase 2

• Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies Start of enrollment: 2008 Aug 01

  Terminated

  Phase 2

• AZD5672 Bioavailability Study in Healthy Male and Female Subjects Start of enrollment: 2009 Mar 01

  Completed

  Phase 1

• A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart Start of enrollment: 2009 Apr 01

  Completed

  Phase 1

• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding. Start of enrollment: 2010 Sep 01

  Completed

  Phase 3

• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding. Start of enrollment: 2010 Sep 01

  Completed

  Phase 3

• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist Start of enrollment: 2010 Sep 01

  Completed

  Phase 3

• Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA) Start of enrollment: 2011 Jan 01

  Terminated

  Phase 3

• A Study of Fostamatinib in Subjects With Impaired Kidney Function Start of enrollment: 2010 Nov 01

  Completed

  Phase 1

• Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA) Start of enrollment: 2011 Jan 01

  Terminated

  Phase 2

• Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy Subjects Start of enrollment: 2011 Mar 01

  Completed

  Phase 1

• Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy Subjects Start of enrollment: 2011 Mar 01

  Completed

  Phase 1

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