Mark Gabriel Lebwohl MD

Dermatology•New York, NY

Dean for Clinical Therapeutics, Professor and Chairman Emeritus of Dermatology, Icahn School of Medicine at Mount Sinai

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5 e 98 stNew York, NY 10029
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Education & Training

Icahn School of Medicine at Mount SinaiResidency, Dermatology, 1981 - 1983
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Internal Medicine, 1978 - 1981
Harvard Medical SchoolClass of 1978

Certifications & Licensure

NY State Medical License 1980 - 2027
American Board of Dermatology Dermatology
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Gold Medal American Academy of Dermatology, 2022
Top MD Consumers Checkbook
Whos Who in Medicine and Healthcare Marquis Whos Who
Super Doctor SuperDoctors.com
Fellow (FAAD) American Academy of Dermatology
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Clinical Trials

LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)
COMPLETED
PHASE3
Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE) Start of enrollment: 2012 Aug 01
Completed
Phase 2
LEO 90100 in the Treatment of Psoriasis Vulgaris
COMPLETED
PHASE2
Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp Start of enrollment: 2013 Mar 01
Completed
Phase 1
Safety and Effectiveness of CNDO 201Trichuris Suis Ova (TSO) for the Treatment of Moderate to Severe Plaque Psoriasis Start of enrollment: 2013 Mar 01
Completed
Phase 1
Phase IIa Study of Multiple Doses of AbGn-168H by iv Infusion in Moderate to Severe Chronic Plaque Psoriasis Patients Start of enrollment: 2013 May 01
Completed
Phase 2
Evaluation of CL Detect™ Rapid Test to Detect Cutaneous Leishmaniasis Start of enrollment: 2013 Jun 01
Completed
Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris Start of enrollment: 2014 Mar 19
Completed
Phase 2
Reduction of Pain Caused by Biologic Drugs in Psoriasis Start of enrollment: 2014 May 01
Completed
Not Applicable
Addition of Excimer Laser to Treatment With Acitretin Tablets for Psoriasis of the Palms and Soles Start of enrollment: 2014 Jun 01
Terminated
Phase 4
A Study of Multiple Doses of AbGn-168H by Intravenous Infusion in Patients With Moderate to Severe Chronic Plaque Psoriasis Start of enrollment: 2014 May 01
Completed
Phase 2
Treatment of Actinic Keratoses (AK) on the Face Start of enrollment: 2015 Mar 01
Completed
Phase 1
LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris Start of enrollment: 2017 Feb 15
Completed
Phase 3
Combined Therapy With Narrow-Band Ultraviolet B Phototherapy and Apremilast for the Treatment of Vitiligo Start of enrollment: 2017 Apr 14
Completed
Phase 2
Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study Start of enrollment: 2019 May 29
ACTIVE_NOT_RECRUITING
PHASE2
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Publications & Presentations

PubMed

Biologics for the Treatment of Moderate-to-Severe Plaque Psoriasis: A Systematic Review and Network Meta-analysis.
Mark G Lebwohl, André Carvalho, Akihiko Asahina, Jianzhong Zhang, Mir Sohail Fazeli
Dermatology and Therapy. 2025-07-01
Targeting the IL-36 receptor with spesolimab mitigates residual inflammation and prevents generalized pustular psoriasis flares.
James G Krueger, Mrinal K Sarkar, Mark G Lebwohl, Akimichi Morita, Kenneth Gordon
The Journal of Clinical Investigation. 2025-07-01
6 citations
Deucravacitinib in plaque psoriasis: Four-year safety and efficacy results from the Phase 3 POETYK PSO-1, PSO-2 and long-term extension trials.
April W Armstrong, Mark Lebwohl, Richard B Warren, Howard Sofen, Akimichi Morita
Journal of the European Academy of Dermatology and Venereology. 2025-07-01

Lectures

Dilemmas and Challenges in Skin Cancer Therapies and Management
American Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/4/2019

Authored Content

How Dermatologists Can Address Obesity to Improve Psoriasis OutcomesMarch 2025

Press Mentions

Decision Trees for Psoriasis: Is There One Best Drug?April 25th, 2025
Risankizumab Makes a Difference in Hard-to-Treat PsoriasisMarch 21st, 2025
Anti–IL-23 Therapy Might Emerge as Best Biologic in Psoriasis if Used Early and at High DosesMarch 20th, 2025
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