MarkBernardLeickMD

PubMed

• Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma.
  Bryan D Choi, Elizabeth R Gerstner, Matthew J Frigault, Mark B Leick, Christopher W Mount, Leonora Balaj, Sarah Nikiforow, Bob S Carter, William T Curry, Kathleen Gall...> ;The New England Journal of Medicine. 2024 Apr 11
• Optimization of a flow cytometry test for routine monitoring of B cell maturation antigen targeted CAR in peripheral blood.
  Won-Ho Lee, Charlotte E Graham, Hadley R Wiggin, Hannah K Nolan, Kiana J Graham, Felix Korell, Mark B Leick, Alexis L Barselau, Estelle Emmanuel-Alejandro, Michael A T...> ;Cytometry. Part B, Clinical Cytometry. 2024 Feb 28
• Mesothelin CAR T-cells secreting anti-FAP/anti-CD3 molecules efficiently target pancreatic adenocarcinoma and its stroma.
  Wehrli, M., Guinn, S., Birocchi, F., Kuo, A., Sun, Y., Larson, R., Almazan, A., Scarfò, I., Bouffard, A., Bailey, S., Anekal, P., Montero Lopis, P., Nieman, L., Song, ...> ;Clinical Cancer Research. 2024 Feb 23
• Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7.
  Michael C Kann, Emily M Schneider, Antonio J Almazan, Isabel C Lane, Amanda A Bouffard, Valentina M Supper, Hana N Takei, Alexander Tepper, Mark B Leick, Rebecca C Lar...> ;Leukemia. 2024 Mar 1
• Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia.
  Boucher, J., Shrestha, B., Vishwasrao, P., Cervantes, E., Ghafoor, T., Reid, K., Spitler, K., Yu, B., Guevara-Patino, J., Leick, M., Betts, B., Maus, M., Davila, M.> ;Molecular Therapy Oncolytics. 2023 Dec 19
• 2 citations
  Genetic retargeting of E3 ligases to enhance CAR T cell therapy.
  Isabel C Lane, Gabriele Kembuan, Jeannie Carreiro, Michael C Kann, William Lin, Amanda A Bouffard, Johannes Kreuzer, Robert Morris, Emily M Schneider, Joanna Y Kim, Ch...> ;Cell Chemical Biology. 2024 Feb 15
• 5 citations
  Chemotherapy-induced reversal of ciltacabtagene autoleucel-associated movement and neurocognitive toxicity.
  Charlotte E Graham, Won-Ho Lee, Hadley R Wiggin, Valentina M Supper, Mark B Leick, Filippo Birocchi, Andrew J Yee, Angelina Petrichenko, John Everett, Frederic D Bushm...> ;Blood. 2023 Oct 5
• 30 citations
  Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.
  Ombrello, A. K., Ombrello, A. K., Melissa R Hines, Tristan E Knight, Kevin O McNerney, Mark B Leick, Tania Jain, Sairah Ahmed, Matthew J Frigault, Joshua A Hill, Micha...> ;Transplantation and Cellular Therapy. 2023 Jul 1
• 10th antibody industrial symposium: new developments in antibody and adoptive cell therapies.
  Ana Antunes, Luis Alvarez-Vallina, Federico Bertoglio, Nicolas Bouquin, Stéphanie Cornen, Francis Duffieux, Pierre Ferré, Raphaëlle Gillet, Christian Jorgensen, Mark B...> ;Mabs. 2023 May 15
• 1 citations
  Multiomics STEP up in correlative analysis of response to CAR T cells.
  Mark B Leick, Marcela V Maus> ;Nature Reviews. Clinical Oncology. 2023 May 1
• 9 citations
  Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma.
  Andrea Schmidts, Ambike A Srivastava, Rishab Ramapriyan, Stefanie R Bailey, Amanda A Bouffard, Daniel P Cahill, Bob S Carter, William T Curry, Gavin P Dunn, Matthew J ...> ;Neuro-Oncology Advances. 2022 Dec 22
• 74 citations
  Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma.
  Nicholas J Haradhvala, Mark B Leick, Katie Maurer, Satyen H Gohil, Rebecca C Larson, Ning Yao, Kathleen M E Gallagher, Katelin Katsis, Matthew J Frigault, Jackson Sout...> ;Nature Medicine. 2022 Sep 1
• Paraneoplastic Pulmonary Alveolar Proteinosis.
  Mark Leick, Yi-Bin Chen> ;American Journal of Respiratory and Critical Care Medicine. 2022 Jun 15
• 42 citations
  Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia.
  Mark B Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D Choi, Amanda A Bouffard, Kathleen Gallagher, Andrea Schmidts, Stefanie R Bailey, Michael C Kann, Ma...> ;Cancer Cell. 2022 May 9
• 47 citations
  Safety and efficacy of tisagenlecleucel in primary CNS lymphoma: a phase 1/2 clinical trial.
  Matthew J Frigault, Jorg Dietrich, Kathleen Gallagher, Mark Roschewski, Justin T Jordan, Deborah Forst, Scott R Plotkin, Daniella Cook, Keagan S Casey, Kevin A Lindell...> ;Blood. 2022 Apr 14
• 3 citations
  Antibody and T-cell responses to SARS-CoV-2 vaccination in myeloproliferative neoplasm patients.
  Joan How, Kathleen M E Gallagher, Yiwen Liu, Katelin Katsis, Eva L Elder, Rebecca C Larson, Mark B Leick, Donna Neuberg, Marcela V Maus, Gabriela S Hobbs> ;Leukemia. 2022 Apr 1
• 123 citations
  CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours.
  Rebecca C Larson, Michael C Kann, Stefanie R Bailey, Nicholas J Haradhvala, Paula Montero Llopis, Amanda A Bouffard, Irene Scarfó, Mark B Leick, Korneel Grauwet, Trish...> ;Nature. 2022 Apr 1
• 4 citations
  Differential T-Cell Immunity to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in mRNA-1273- and BNT162b2-Vaccinated Individuals.
  Kathleen M E Gallagher, Mark B Leick, Rebecca C Larson, Trisha R Berger, Katelin Katsis, Jennifer Y Yam, Marcela V Maus> ;Clinical Infectious Diseases. 2022 Aug 24
• 27 citations
  Blockade or Deletion of IFNγ Reduces Macrophage Activation without Compromising CAR T-cell Function in Hematologic Malignancies.
  Stefanie R Bailey, Sonika Vatsa, Rebecca C Larson, Amanda A Bouffard, Irene Scarfò, Michael C Kann, Trisha R Berger, Mark B Leick, Marc Wehrli, Andrea Schmidts, Harris...> ;Blood Cancer Discovery. 2022 Mar 1
• A glimpse into what happens after PTCy.
  Mark Leick, Yi-Bin Chen> ;Blood. 2022 Jan 27
• 44 citations
  Single-center experience using anakinra for steroid-refractory immune effector cell-associated neurotoxicity syndrome (ICANS).
  Marc Wehrli, Kathleen Gallagher, Yi-Bin Chen, Mark B Leick, Steven L McAfee, Areej R El-Jawahri, Zachariah DeFilipp, Nora Horick, Paul O'Donnell, Thomas Spitzer, Bimal...> ;Journal for Immunotherapy of Cancer. 2022 Jan 1
• 34 citations
  Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy.
  Peter Miller, Adam S. Sperling, Elliott J. Brea, Mark B. Leick, Geoffrey Fell, Max Jan, Satyen H. Gohil, Yu-Tzu Tai, Nikhil C. Munshi, Catherine J. Wu, Donna Neuberg, ...> ;Blood Advances. 2021 Aug 10
• 26 citations
  SARS -CoV-2 T-cell immunity to variants of concern following vaccination
  Kathleen Gallagher, Mark B. Leick, Rebecca C. Larson, Trisha R. Berger, Katelin Katsis, Jennifer Y. Yam, Gabrielle Brini, Korneel Grauwet, Marcela V. Maus> ;Biorxiv. 2021 May 3
• 3 citations
  Telephone.
  Mark B Leick> ;The New England Journal of Medicine. 2020 Dec 10
• 19 citations
  Clinical Perspective: Treatment of Aggressive B Cell Lymphomas with FDA-Approved CAR-T Cell Therapies.
  Mark B. Leick, Marcela V. Maus, Matthew J. Frigault> ;Molecular Therapy. 2021 Feb 3
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Lectures

• Telephone 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Telephone 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019