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Office
401 N. Broadway
Baltimore, MD 21231Phone+1 410-955-8964- Is this information wrong?
Education & Training
Johns Hopkins UniversityFellowship, Medical Oncology, 2016 - 2018
University of Pennsylvania Health SystemResidency, Internal Medicine, 2012 - 2015
Perelman School of Medicine at the University of PennsylvaniaClass of 2012
Certifications & Licensure
MD State Medical License 2015 - 2025
NC State Medical License 2021 - 2022
PA State Medical License 2012 - 2022- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Clinical Trials
- TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers Start of enrollment: 2019 Mar 20
- National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer Start of enrollment: 2021 Jul 28
- DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma Start of enrollment: 2020 Apr 20
Publications & Presentations
PubMed
- First-in-human Phase I Trial of TPST-1120, an Inhibitor of PPARα, as Monotherapy or in Combination with Nivolumab, in Patients with Advanced Solid Tumors.Mark Yarchoan, John D Powderly, Bruno R Bastos, Thomas B Karasic, Oxana V Crysler, Pamela N Munster, Meredith A McKean, Leisha A Emens, Yvonne M Saenger, Yasser Ged, R...> ;Cancer Research Communications. 2024 Apr 18
- Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial.Mark Yarchoan, Edward J Gane, Thomas U Marron, Renzo Perales-Linares, Jian Yan, Neil Cooch, Daniel H Shu, Elana J Fertig, Luciane T Kagohara, Gabor Bartha, Josette Nor...> ;Nature Medicine. 2024 Apr 1
- Exploring the Clinical Use of Molecular Profiling of Intrahepatic Cholangiocarcinoma in a Comprehensive Multidisciplinary Clinic.Julia Purchla, Elie M Ghabi, William R Burns, Kelly J Lafaro, Richard A Burkhart, John L Cameron, Mark Yarchoan, Christopher R Shubert, Marina Baretti, Jin He> ;Journal of the American College of Surgeons. 2024 Apr 1
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Journal Articles
- Effects of B Cell–Activating Factor on Tumor ImmunityMark Yarchoan, MD, The Journal of Clinical Investigation
- Development of Tumor Mutation Burden as an Immunotherapy Biomarker: Utility for the Oncology ClinicMark Yarchoan, Elizabeth Jaffee, Annals of Oncology
- Immuno-Oncology Trial Endpoints: Capturing Clinically Meaningful ActivityElad Sharon, Patrick M Forde, Valsamo Anagnostou, Hao Wang, Franco Verde, Mark Yarchoan, Clinical Cancer Research
Authored Content
- Effects of B Cell–Activating Factor on Tumor ImmunityMay 2020
Press Mentions
Tempest Provides ASCO KOL Feedback on TPST-1120 Clinical Results and Updated Financial GuidanceJune 9th, 2022- The Society for Immunotherapy of Cancer (SITC) Invites You to Attend the Virtual Press Briefing of the Society’s 36th Anniversary Annual MeetingNovember 2nd, 2021
- Cancer Risks in Solid Organ Transplant Recipients: Results from a Comprehensive Analysis of 72 Cohort StudiesNovember 29th, 2020
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Hospital Affiliations
Johns Hopkins HospitalBaltimore, Maryland
Johns Hopkins Bayview Medical CenterBaltimore, Maryland
Johns Hopkins Howard County Medical CenterColumbia, Maryland
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