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Enders Reserach Building Room 507300 Longwood AvenueBoston, MA 02115
Phone+1 617-919-2993
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Summary
- Markus Frank, M.D., is Professor of Pediatrics and Associate Professor of Dermatology at Harvard Medical School and Co-Leader of the Harvard Stem Cell Institute Skin Program. After graduating from Harvard University with an A.B. degree in Biochemical Sciences, earning his M.D. degree from the University of Heidelberg, and training in internal medicine and nephrology at Albert Einstein College of Medicine and Brigham and Women’s Hospital, respectively, he established a leading laboratory at Boston Children's Hospital focused on ABCB5+ stem cells and cancer stem cell-targeted therapies. His major accomplishments include cloning and characterization of the ABCB5 gene and the discovery that ABCB5 identifies immunoregulatory dermal mesenchymal stem cells, which enabled successful development of a novel cell therapeutic drug (Amesanar) for treatment of chronic venous ulcer (CVU) disease.
Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 1997 - 2001
Montefiore Medical Center/Albert Einstein College of Medicine (Moses and Weiler Campuses)Residency, Internal Medicine, 1994 - 1997
Ruprecht Karl University Faculty of MedicineClass of 1992
Certifications & Licensure
MA State Medical License 1997 - 2028
National Board of Physicians and Surgeons Internal Medicine
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2011
Publications & Presentations
PubMed
- 2 citationsAccelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma.Catherine A A Lee, Siyuan Wu, Yuen Ting Chow, Eric Kofman, Valencia Williams
The Journal of Investigative Dermatology. 2024-07-01 - 4 citationsProtocol for isolating human BCAM-positive corneal progenitor cells by flow cytometry and cell sorting.Yuzuru Sasamoto, Philip C Yeung, Johnathan Tran, Markus H Frank, Natasha Y Frank
STAR Protocols. 2023-09-15 - Corrigendum to ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa [Cytotherapy 25 (2023) 782-...Kathrin Dieter, Elke Niebergall-Roth, Cristina Daniele, Silvia Fluhr, Natasha Y Frank
Cytotherapy. 2023-09-01
Press Mentions
Researchers Regrow Corneas, First Known Tissue Grown from an Adult Human Stem CellJuly 2nd, 2014- The Cellular Root of Colorectal Cancers?June 10th, 2011
Grant Support
- ABCB5-positive stem cells for LSCD therapyBOSTON CHILDREN'S HOSPITAL2016–2028
- Multicomponent Therapy for Age-related Skin Stem Cell DeficiencyBRIGHAM AND WOMEN'S HOSPITAL2022–2027
- Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHDBRIGHAM AND WOMEN'S HOSPITAL2022–2025
- Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHDBRIGHAM AND WOMEN'S HOSPITAL2022–2025
- Melanoma Stem Cells, Vasculogenesis And Neoplastic ProgressionNational Cancer Institute2008–2011
Research History
- Professor of Pediatrics, Harvard Medical School2025 - Present
Professional Memberships
- Member
- Member
Other Languages
- German
External Links
- Boston Children's Hospital - Markus Frankhttps://research.childrenshospital.org/researchers/markus-frank
- Harvard Stem Cell Institute - Markus Frankhttps://www.hsci.harvard.edu/people/markus-frank-md
- ASCI - Markus Frankhttps://data.the-asci.org/controllers/asci/DirectoryController.php?action=profile&entryId=500835
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