MarlaJKellerMDFIDSA

Infectious Disease • Bronx, NY

HIV/AIDS Medicine

Prof, Medicine, Infectious Diseases; OB/GYN and Women's Health, Albert Einstein College of Medicine

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Office
1300 Morris Park Ave
Block Building, Room 512
Bronx, NY 10461
Phone(718) 430-3240
Fax(718) 430-8879
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Education & Training

Brigham and Women's HospitalFellowship, Infectious Disease, 1996 - 1999
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1993 - 1996
NYU School of MedicineClass of 1993

Certifications & Licensure

NY State Medical License 1998 - 2021
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com

Clinical Trials

Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002) Start of enrollment: 2017 Jan 01Marla J Keller, MD
Safety of Acidform Lubricant (Amphora) in Women at Low Risk for HIV-1 Infection Start of enrollment: 2009 Feb 01Keller, M.,Lee, A.
Effect of Repeated Applications of Tenofovir Gel on Mucosal Mediators of Immunity and Intrinsic Antimicrobial Activity of Cervicovaginal Secretions in Women at Low Risk for HIV-1 Infection Herold, B.,Keller, M.

Publications & Presentations

PubMed

Acceptability of a Tenofovir Disoproxil Fumarate Intravaginal Ring for HIV Pre-Exposure Prophylaxis Among Sexually Active Women.
April Dobkin, Jessica McWalters, Rebecca Barnett, Laurie L. Ray, Lilia Espinoza, Aileen P. McGinn, Jessica Atrio, Marla J. Keller> ;Sexually Transmitted Diseases. 2020 Dec 1
Primary HPV and Molecular Cervical Cancer Screening in US Women Living with HIV.
Howard D. Strickler, Marla J. Keller, Nancy A. Hessol, Isam-Eldin Eltoum, Mark H. Einstein, Philip E. Castle, L. Stewart Massad, Lisa Flowers, Lisa Rahangdale, Jessica...> ;Clinical Infectious Diseases. 2020 Sep 3
Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19.
Marla J. Keller, Elizabeth A. Kitsis, Shitij Arora, Jen-Ting Chen, Shivani Agarwal, Michael W. Ross, Yaron Tomer, William N. Southern> ;Journal of Hospital Medicine. 2020 Aug 1
A counterpoint to "training the translational workforce: expanding beyond translational research to include translational science".
Paul R. Marantz, Marla J. Keller, Emma A. Meagher> ;Journal of clinical and translational science. 2020 Apr 6
Faecal microbiota transplantation for diarrhoea-predominant irritable bowel syndrome: a double-blind, randomised, placebo-controlled trial.
Olga C. Aroniadis, Lawrence J. Brandt, Caterina Oneto, Paul Feuerstadt, Alex Sherman, Allan W. Wolkoff, Zain Kassam, Rotem Gura Sadovsky, Ryan J. Elliott, Shrish Budre...> ;The Lancet Gastroenterology & Hepatology. 2019 Sep 1
Tenofovir disoproxil fumarate intravaginal ring for HIV pre-exposure prophylaxis in sexually active women: a phase 1, single-blind, randomised, controlled trial
Marla J. Keller, Lianna F. Wood, James M. Billingsley, Laurie L. Ray, Jessica Goymer, Shada Sinclair, Aileen P. McGinn, Mark A. Marzinke, Bruce Frank, Sujatha Srinivas...> ;The Lancet HIV. 2019 Aug 1
Impact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome.
Marla J. Keller, Ashley M. Huber, Lilia Espinoza, Myrna G. Serrano, Hardik I. Parikh, Gregory A. Buck, Jeremy A Gold, Yiqun Wu, Tao Wang, Betsy C. Herold> ;The Journal of Infectious Diseases. 2019 Jul 31
Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection.
Kerry Murphy, Marla J. Keller, Kathryn Anastos, Shada Sinclair, J. Cooper Devlin, Qiuhu Shi, Donald R. Hoover, Brian Starkman, Jamie McGillick, Caroline Mullis, Howard...> ;PLOS ONE. 2019 Apr 26
Racial differences in human papilloma virus types amongst United States women with HIV and cervical precancer
Marla J. Keller, Robert D. Burk, Leslie S. Massad, Isam Eldin Eltoum, Nancy A. Hessol, Kathryn Anastos, Xianhong Xie, Howard Minkoff, Xiaonan Xue, Laura Reimers, Mark ...> ;AIDS. 2018 Nov 28
Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics.
Ekaterina Taneva, Shada Sinclair, Pedro M. M. Mesquita, Brian Weinrick, Scott A. Cameron, Natalia Cheshenko, Kerry Reagle, Bruce Frank, Sujatha Srinivasan, David N. Fr...> ;JCI insight. 2018 Jul 12
Acceptability of a Tenofovir Disoproxil Fumarate Vaginal Ring for HIV Prevention Among Women in New York City
Marla Keller, MD> ;AIDS and Behavior. 2017 Nov 18
2 citations
Cervical cancer screening intervals and management for women living with HIV: A risk benchmarking approach
Hilary A. Robbins, Howard D. Strickler, L. Stewart Massad, Christopher B. Pierce, Teresa M. Darragh, Howard Minkoff, Marla J. Keller, Margaret A. Fischl, Joel M. Palef...> ;AIDS. 2017 Apr 24
Role of Interleukin 32 in Human Immunodeficiency Virus Reactivation and Its Link to Human Immunodeficiency Virus-Herpes Simplex Virus Coinfection.
Pedro M. M. Mesquita, Paula Preston-Hurlburt, Marla J. Keller, Nalini K. Vudattu, Lilia Espinoza, Michelle Altrich, Kathryn Anastos, Kevan C. Herold, Betsy C. Herold> ;The Journal of Infectious Diseases. 2016 Dec 22
In vitro inhibition of human papillomavirus following use of a carrageenan-containing vaginal gel☆☆☆☆☆☆
Akiva P. Novetsky, Marla J. Keller, Ana Gradissimo, Zigui Chen, Stephanie L. Morgan, Xiaonan Xue, Howard D. Strickler, José A. Fernández-Romero, Robert D. Burk, Mark H...> ;Gynecologic Oncology. 2016 Nov 1
Multitype Infections With Human Papillomavirus: Impact of Human Immunodeficiency Virus Coinfection
Leslie S. Massad, Marla J. Keller, Xianhong Xie, Howard Minkoff, Joel M. Palefsky, Gypsyamber DʼSouza, Christine Colie, Maria Villacres, Howard D. Strickler> ;Sexually Transmitted Diseases. 2016 Sep 15
Longitudinal Assessment of Systemic and Genital Tract Inflammatory Markers and Endogenous Genital Tract E. coli Inhibitory Activity in HIV-Infected and Uninfected Women.
Marla J. Keller, Aileen P. McGinn, Yungtai Lo, Ashley Huber, Lilia Espinoza, Howard Minkoff, Christine Colie, Marek Nowicki, Gypsyamber D'Souza, Kathryn Anastos> ;American Journal of Reproductive Immunology. 2016 May 5
4 citations
A phase 1 randomized placebo-controlled safety and pharmacokinetic trial of a tenofovir disoproxil fumarate vaginal ring.
Marla J. Keller, Pedro M. M. Mesquita, Mark A. Marzinke, Ryan S. Teller, Lilia Espinoza, Jessica Atrio, Yungtai Lo, Bruce Frank, Sujatha Srinivasan, David N. Fredricks...> ;AIDS. 2016 Mar 13
Loss of Innate Host Defense Following Unprotected Vaginal Sex
Natasha Nakra, Rebecca Pellett Madan, Niall Buckley, Ashley M. Huber, Jamie L. Freiermuth, Lilia Espinoza, Jennifer Walsh, Urvi M. Parikh, Kerri J. Penrose, Marla J. K...> ;The Journal of Infectious Diseases. 2016 Mar 1
Screening for Human Papillomavirus-Associated Cervical Disease in HIV-Infected Women.
Marla J. Keller> ;Topics in antiviral medicine. 2015 Oct 1
2 citations
Cervical Precancer Risk in HIV-Infected Women Who Test Positive for Oncogenic Human Papillomavirus Despite a Normal Pap Test
Marla J. Keller, Robert D. Burk, L. Stewart Massad, Isam Eldin Eltoum, Nancy A. Hessol, Philip E. Castle, Kathryn Anastos, Xianhong Xie, Howard Minkoff, Xiaonan Xue, G...> ;Clinical Infectious Diseases. 2015 Jul 17
9 citations
Nevirapine concentration in hair samples is a strong predictor of virologic suppression in a prospective cohort of HIV-infected patients
Sanjiv M. Baxi, Ruth M. Greenblatt, Peter Bacchetti, Chengshi Jin, Audrey L. French, Marla J. Keller, Michael Augenbraun, Stephen J. Gange, Chenglong Liu, Wendy J. Mac...> ;PLOS ONE. 2015 Jun 8
26 citations
TLR7 induces anergy in human CD4(+) T cells.
Dominguez-Villar, M., Gautron, A., de Marcken, M., Keller, M. J., Hafler, D. A.> ;Nature immunology. 2014 Nov 18
4 citations
Long-term cumulative detection of human papillomavirus among HIV seropositive women.
Leslie S. Massad, Xianhong Xie, Robert D. Burk, Marla J. Keller, Howard Minkoff, Gypsyamber DʼSouza, D. H. Watts, Joel M. Palefsky, Mary Young, Alexandra M. Levine, Ma...> ;AIDS. 2014 Nov 13
Plasmodium falciparum Infection Does Not Affect Human Immunodeficiency Virus Viral Load in Coinfected Rwandan Adults
Krishanthi Subramaniam, Rebeca M. Plank, Nina H. Lin, Adam E. Goldman-Yassen, Emil Ivan, Carlos Becerril, Kimdar Sherefa Kemal, Moonseong Heo, Marla J. Keller, Eugene ...> ;Open Forum Infectious Diseases. 2014 Sep 1
1 citations
Comparison of the vaginal microbial communities in women with recurrent genital HSV receiving acyclovir intravaginal rings.
Luke K. Ursell, Manjula Gunawardana, Simon Chang, Madeline Mullen, John A. Moss, Betsy C. Herold, Marla J. Keller, Daniel McDonald, Antonio Gonzalez, Rob Knight, Marc ...> ;Antiviral Research. 2014 Feb 1
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Press Mentions

Montefiore and Einstein Hospitals Awarded Millions for COVID-19 Plasma TreatmentAugust 20, 2020 10:43
Montefiore, Einstein Publish COVID-19 Steroid StudyAugust 01, 2020 09:22
Common Blood Test Can Identify Which Patients Can Benefit or Be Harmed by Steroid Use for COVID-19 TreatmentJuly 28, 2020 09:37
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Grant Support

Clinical Study To Measure Pharmacokinetics, Pharmacodynamics And Safety Of A TdfNational Institute Of Allergy And Infectious Diseases2011
Novel Mucosal Models Predictive Of Microbicide SafetyNational Institute Of Allergy And Infectious Diseases2010–2011
Safety Of Non-Medicated Intravaginal Rings For Microbicide DeliveryNational Institute Of Allergy And Infectious Diseases2010
Microbicide Effects On Efficacy, Safety, Innate ImmunityNational Institute Of Allergy And Infectious Diseases2007–2010
Novel Mucosal Models Predictive Of Microbicide SafetyNational Institute Of Allergy And Infectious Diseases2008–2009
Effects Of Hormones On Mucosal Immune Mediators Across The Menstrual CycleNational Center For Research Resources2007–2008
The Efficacy Of Samma And Its Leading Derivatives Against HIV-1National Center For Research Resources2007
Microbicide Effects On Efficacy, Safety, Innate ImmunityNational Institute Of Allergy And Infectious Diseases2005–2007
To Evaluate The Efficacy Of Samma And Its Leading Derivatives Against HIV-1National Center For Research Resources2006
Effect Of Repeated Applications Of PRO 2000/5 Gel (P) On Inflammatory MediatorsNational Center For Research Resources2006
Effects Of HIV On Bone Mass In The ElderlyNational Center For Research Resources2005–2006
Multitargeted Microbicide Combinations To Block HIVNational Center For Research Resources2004–2006
Effect Of Repeated Applications Of PRO 2000/5 Gel (P) On Inflammatory MediatoNational Center For Research Resources2005
To Evaluate The Efficacy Of Samma And Its Leading Derivatives Against HIV-1 U...National Center For Research Resources2004
In Vivo Antiviral &Inflammatory Effects Of MicrobicidesEunice Kennedy Shriver National Institute Of Child Health &Human Development2002