MartinWiesenfeldMD

Oncology • Cedar Rapids, IA

Physician

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Office
701 10th St Se
Hpcc 3rd Floor
Cedar Rapids, IA 52403
Phone+1 319-363-8303

Fax+1 319-364-4659
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Education & Training

University of Iowa Hospitals and ClinicsFellowship, Hematology and Medical Oncology, 1978 - 1979
University of Iowa Hospitals and ClinicsFellowship, Hematology and Medical Oncology, 1977 - 1978
Hennepin HealthcareResidency, Internal Medicine, 1974 - 1977
Hennepin HealthcareInternship, Transitional Year, 1973 - 1974
University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1973

Certifications & Licensure

IA State Medical License 1977 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification MOSAIQ EMR, Elekta, 2012

Clinical Trials

Rituximab and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma Start of enrollment: 2005 May 01
Completed
Phase 3
Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma Start of enrollment: 2006 Mar 24
Completed
Phase 1, Phase 2
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Start of enrollment: 2006 Sep 15
Completed
Phase 2
Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating Patients With Metastatic or Unresectable Locally Advanced Small Bowel Cancer Start of enrollment: 2007 May 01
Completed
Phase 2
L-Arginine Supplements in Treating Women Who Are Cancer Survivors Start of enrollment: 2007 May 01
Completed
Not Applicable
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Start of enrollment: 2009 Mar 01
Completed
Phase 1, Phase 2
Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer Start of enrollment: 2007 Sep 01
Completed
Phase 3
Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma Start of enrollment: 2008 Apr 01
Active, not recruiting
Phase 3
Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer Start of enrollment: 2008 Jul 30
Completed
Phase 2
Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination Chemotherapy Start of enrollment: 2008 Jun 15
Completed
Phase 3
Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer Start of enrollment: 2008 Oct 13
Completed
Phase 3
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia Start of enrollment: 2009 Jan 29
Active, not recruiting
Phase 3
Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary Start of enrollment: 2009 Sep 01
Completed
Phase 2
Home-Based Programs for Improving Sleep in Cancer Survivors Start of enrollment: 2010 Apr 01
Terminated
Phase 2
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Start of enrollment: 2010 Sep 21
Active, not recruiting
Phase 2
Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer Start of enrollment: 2011 Jan 01
Terminated
Phase 3
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Publications & Presentations

PubMed

107 citations
Prognostic Value of Proliferation, Apoptosis, Defective DNA Mismatch Repair, and p53 Overexpression in Patients With Resected Dukes' B2 or C Colon Cancer: A North Cent...
Megan M. Garrity, Lawrence J. Burgart, Michelle R. Mahoney, Harold E. Windschitl, Muhammad Salim, Martin Wiesenfeld, James E. Krook, John C. Michalak, Richard M. Goldb...> ;Journal of Clinical Oncology. 2016 Sep 21
6 citations
Phase II interventional study (N0337) of capecitabine in combination with vinorelbine and trastuzumab for first- or second-line treatment of HER2-positive metastatic b...
Winston Tan, Jacob B. Allred, Muhammad Salim, Patrick J. Flynn, Paul A. S. Fishkin, Philip J. Stella, Martin Wiesenfeld, Albert M. Bernath, Tom R. Fitch, Edith A. Perez> ;Clinical Breast Cancer. 2012 Apr 1
Randomized phase II trial of panitumumab, erlotinib, and gemcitabine (PGE) versus erlotinib-gemcitabine (GE) in patients with untreated, metastatic pancreatic adenocar...
Kim GP, Foster NR, Salim M, Flynn PJ, Moore DF, Zon R, Mowat RB, Wiesenfeld M, McCullough AE, Alberts SR> ;J. Clin. Oncol.. 2011-05-20
N0337: Phase II study of capecitabine in combination with vinorelbine and trastuzumab for the first or second treatment of HER2+ metastatic breast cancer.
Tan W, Allred J, Salim M, Flynn P, Kugler JW, Stella PJ, Wiesenfeld M, Bernath AM, Fitch TR, Perez EA> ;J. Clin. Oncol.. 2009-05-20
26 citations
Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results
Marta Santisteban, Jan C. Buckner, Joel M. Reid, Wenting Wu, Bernd W. Scheithauer, Matthew M. Ames, Sara J. Felten, Daniel A. Nikcevich, Martin Wiesenfeld, Kurt A. Jae...> ;Journal of Neuro-Oncology. 2009 Jan 1
125 citations
Phase II Trial of Sorafenib in Patients With Metastatic Breast Cancer Previously Exposed to Anthracyclines or Taxanes: North Central Cancer Treatment Group and Mayo Cl...
Alvaro Moreno-Aspitia, Roscoe F. Morton, David W. Hillman, Wiltna L. Lingle, Kendrith M. Rowland, Martin Wiesenfeld, Patrick J. Flynn, Tom R. Fitch, Edith A. Perez> ;Journal of Clinical Oncology. 2009 Jan 1
15 citations
Subcutaneous interleukin-4 (IL-4) for relapsed and resistant non-Hodgkin lymphoma: a phase II trial in the North Central Cancer Treatment Group, NCCTG 91-78-51.
David M. Kurtz, Loren K. Tschetter, Jacob B. Allred, Susan Geyer, Paul J. Kurtin, Wesley D. Putnam, Kendrith M. Rowland, Martin Wiesenfeld, Gamini S. Soori, Richard C....> ;Leukemia & Lymphoma. 2007 Jul 1
BAY 43-9006 as single oral agent in patients with metastatic breast cancer previously exposed to anthracycline and/or taxane.
Moreno-Aspitia A, Hillman DW, Wiesenfeld M, Hobday TJ, Rowland KM, Northfelt DW, Tenner KS, Palmieri FM, Perez EA> ;J. Clin. Oncol.. 2006-06-20
20 citations
Weekly carboplatin and paclitaxel in elderly non-small-cell lung cancer patients (≥65 years of age): A phase II North Central Cancer Treatment Group study
Aminah Jatoi, Philip J. Stella, Shauna Hillman, James A. Mailliard, Stephanie Vanone, Edith A. Perez, Michael W. Cannon, Susan Geyer, Martin Wiesenfeld, James R. Jett> ;American Journal of Clinical Oncology. 2003 Oct 1
9 citations
Randomized phase II study of daily versus continuous-infusion schedules of topotecan in the treatment of extensive-stage small cell lung cancers
Paul L. Schaefer, Randolph S. Marks, Michelle R. Mahoney, Jeff A. Sloan, Mitchell D. Bauman, Henry D. Tazelaar, John W. Kugler, James A. Mailliard, Larry P. Ebbert, Ma...> ;American Journal of Clinical Oncology. 2003 Jun 1
51 citations
Comparison of nicotine patch alone versus nicotine nasal spray alone versus a combination for treating smokers: a minimal intervention, randomized multicenter trial in...
Gary A. Croghan, Jeff A. Sloan, Ivana T. Croghan, Paul J. Novotny, Richard D. Hurt, Wanda L. DeKrey, James A. Mailliard, Larry P. Ebbert, Debra K. Swan, Daniel J. Wals...> ;Nicotine & Tobacco Research. 2003 Jan 1
22 citations
Gemcitabine and oxaliplatin for patients with advanced or metastatic pancreatic cancer: a North Central Cancer Treatment Group (NCCTG) phase I study
Steven R. Alberts, P. M. Townley, Richard M. Goldberg, Steven Cha, Dennis F. Moore, James E. Krook, Henry C. Pitot, Tom R. Fitch, M. Wiesenfeld, James A. Mailliard, Da...> ;Annals of Oncology. 2002 Apr 1
12 citations
A phase II trial of edatrexate, vinblastine, adriamycin, cisplastin, and filgrastim (EVAC/G-CSF) in patients with non-small-cell carcinoma of the lungs: a North Centra...
Gerardo Colon-Otero, Robert D. Niedringhaus, Shauna Hillman, Susan Geyer, Jeff A. Sloan, James E. Krook, Harold E. Windschitl, Randolph S. Marks, Martin Wiesenfeld, Lo...> ;American Journal of Clinical Oncology. 2001 Dec 1
57 citations
A Simple Stratification Factor Prognostic for Survival in Advanced Cancer: The Good/Bad/Uncertain Index
Jeff A. Sloan, Charles L. Loprinzi, John A. Laurine, Paul J. Novotny, Delfino Vargas-Chanes, James E. Krook, Michael J. O'Connell, John W. Kugler, Maria Tria Tirona, C...> ;Journal of Clinical Oncology. 2001 Aug 1
33 citations
Significance of neuron-specific enolase levels before and during therapy for small cell lung cancer.
James A. Bonner, Jeff A. Sloan, Kendrith M. Rowland, George G. Klee, John W. Kugler, James A. Mailliard, Martin Wiesenfeld, James E. Krook, Andrew Maksymiuk, Edward G....> ;Clinical Cancer Research. 2000 Feb 1
32 citations
Prospectively randomized North Central Cancer Treatment Group trial of intensive-course fluorouracil combined with the l-isomer of intravenous leucovorin, oral leucovo...
Richard M. Goldberg, A K Hatfield, Michael J. Kahn, D. J. Sargent, James A. Knost, Michael J. O'Connell, James E. Krook, James A. Maillard, Martin Wiesenfeld, Paul L. ...> ;Journal of Clinical Oncology. 1997 Nov 1
10 citations
Phase II study of 5-fluorouracil and leucovorin in recurrent primary brain tumor
Terrence L. Cascino, Michael H. Veeder, Jan C. Buckner, Judith R. O'Fallon, Martin Wiesenfeld, Ralph Levitt, Richard M. Goldberg, Steven A. Kuross, Roscoe F. Morton, B...> ;Journal of Neuro-Oncology. 1996 Dec 1
48 citations
Controlled clinical trial of interferon-gamma as postoperative surgical adjuvant therapy for colon cancer.
Martin Wiesenfeld, Michael J. O'Connell, Harry S. Wieand, Nick J. Gonchoroff, John H. Donohue, R J Fitzgibbons, James E. Krook, James A. Mailliard, James B. Gerstner, ...> ;Journal of Clinical Oncology. 1995 Sep 1
23 citations
Pilot study of human recombinant interferon gamma and accelerated hyperfractionated thoracic radiation therapy in patients with unresectable stage IIIA/B nonsmall cell...
Edward G Shaw, Richard L Deming, Edward T Creagan, Suresh G. Nair Md, John Q. Su, Ralph Levitt, Preston D Steen, Martin Wiesenfeld, James A. Mailliard> ;International Journal of Radiation Oncology, Biology, Physics. 1995 Feb 15
10 citations
Phase II trial of edatrexate in small cell lung cancer
Martin Wiesenfeld, James R. Jett, John Q. Su, Theodore A. Braich, Carl G. Kardinal, James A. Mailliard, Michael H. Veeder, Roscoe F. Morton, John C. Michalak> ;Cancer. 1994 Feb 15
48 citations
Sequencing and schedule effects of cisplatin plus etoposide in small- cell lung cancer: results of a North Central Cancer Treatment Group randomized clinical trial
Andrew Maksymiuk, James R. Jett, John D. Earle, John Q. Su, F A Diegert, James A. Mailliard, Carl G. Kardinal, James E. Krook, Michael H. Veeder, Martin Wiesenfeld> ;Journal of Clinical Oncology. 1994 Jan 1
34 citations
Combined doxorubicin and alpha‐interferon therapy of advanced hepatocellular carcinoma
Carl G. Kardinal, Charles G. Moertel, Harry S. Wieand, Allan J. Schutt, Michael J. O'Connell, Keith Wright, Martin Wiesenfeld, Loren K. Tschetter, James E. Krook> ;Cancer. 1993 Apr 1
38 citations
Pilot Study of Accelerated Hyperfractionated Thoracic Radiation Therapy Plus Concomitant Etoposide and Cisplatin Chemotherapy in Patients With Unresectable Stage III N...
Edward G. Shaw, William L. McGinnis, James R. Jett, John Q. Su, Albert R. Frank, James A. Mailliard, Roland E. Engel, Martin Wiesenfeld, Kendrith M. Rowland> ;Journal of the National Cancer Institute. 1993 Feb 17
7 citations
Phase II trial of recombinant leukocyte A interferon (IFN-alpha 2A) plus 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and the combination cimetidine with BCNU in patien...
Roscoe F. Morton, Edward T. Creagan, Daniel J. Schaid, Carl G. Kardinal, Greg W. McCormack, Michael S. Mchale, Martin Wiesenfeld> ;American Journal of Clinical Oncology. 1991 Apr 1
28 citations
Phase II evaluation of infusional etoposide and cisplatin in patients with recurrent astrocytoma.
Jan C. Buckner, L. D. Brown, Terrence L. Cascino, James B. Gerstner, James E. Krook, M. W. Westberg, Martin Wiesenfeld, Judith R. O'Fallon, Bernd W. Scheithauer> ;Journal of Neuro-Oncology. 1990 Dec 1
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Grant Support

Cedar Rapids Oncology ProjectNational Cancer Institute1993–2009
Cedars Rapids Oncology ProjectNational Cancer Institute1990–1992

Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

Mercy Iowa CityIowa City, Iowa
UnityPoint Health - St. Luke's HospitalCedar Rapids, Iowa