Mary EllenKleinhenzMD

Pulmonology • San Francisco, CA

Cystic Fibrosis, Lung Transplantation Medicine, Pleural Disease

Health Sciences Clinical Professor, Medicine, UCSF School of Medicine

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Office
400 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-353-4145

Fax+1 415-353-4166
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Summary

Dr. Mary Ellen Kleinhenz is a pulmonologist in San Francisco, CA and practices at UCSF Medical Center. She received her medical degree from Perelman School of Medicine at the University of Pennsylvania and has been in practice 42 years. She specializes in cystic fibrosis, lung transplantation medicine, and Bronchiectasis from causes other than cystic fibrosis. She is experienced in transplant pulmonology and cystic fibrosis.

Education & Training

University of Alabama Medical CenterResidency, Internal Medicine, 1975 - 1978
Perelman School of Medicine at the University of PennsylvaniaClass of 1975

Certifications & Licensure

CA State Medical License 2004 - 2026
OH State Medical License 1978 - 1992
AL State Medical License Active through 1976
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Publications & Presentations

PubMed

3 citations
Development of the Lung Transplant Frailty Scale (LT-FS).
Jonathan P Singer, Jason D Christie, Joshua M Diamond, Michaela A Anderson, Luke A Benvenuto, Ying Gao, Selim M Arcasoy, David J Lederer, Daniel Calabrese, Ping Wang, ...> ;The Journal of Heart and Lung Transplantation. 2023 Jul 1
1 citations
Subphenotypes of frailty in lung transplant candidates.
Jonathan P Singer, Carolyn S Calfee, Kevin Delucchi, Joshua M Diamond, Michaela A Anderson, Luke A Benvenuto, Ying Gao, Ping Wang, Selim M Arcasoy, David J Lederer, St...> ;American Journal of Transplantation. 2023 Apr 1
1 citations
Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.
Anobel Y Odisho, Andrew W Liu, Ali R Maiorano, M Olivia A Bigazzi, Eli Medina, Lorriana E Leard, Rupal Shah, Aida Venado, Alyssa Perez, Jeffrey Golden, Mary Ellen Klei...> ;The Journal of Heart and Lung Transplantation. 2023 Jun 1
2 citations
NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.
Daniel R Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J Tian, Emily A Aminian, Kristin M Wang, Avishai Shemesh, Elman B Punzala...> ;JCI Insight. 2022 Dec 22
2 citations
Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.
Nicholas A Kolaitis, Ying Gao, Allison Soong, John R Greenland, Steven R Hays, Jeffrey A Golden, Aida Venado, Lorriana E Leard, Rupal J Shah, Mary Ellen Kleinhenz, Pat...> ;Thorax. 2022 Sep 1
4 citations
Enabling antibiotic allergy evaluations and reintroduction of first-line antibiotics for patients with cystic fibrosis.
Karen M. Anstey, Lei Choi, Diana Dawson, Mary Ellen Kleinhenz, Iris M. Otani> ;Annals of Allergy, Asthma & Immunology. 2021 May 25
4 citations
The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation
C.L. DeBolt, Ying Gao, N. Sutter, Allison Soong, Lorriana E. Leard, J.A. Golden, Mary Ellen Kleinhenz, Daniel R Calabrese, John R. Greenland, Aida Venado, Steven R. Ha...> ;Clinical Transplantation. 2021 Mar 7
10 citations
Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates
J. Maheshwari, Nicholas A. Kolaitis, Michaela R. Anderson, Luke Benvenuto, Ying Gao, Patricia P. Katz, John R. Greenland, Paul J. Wolters, Kenneth E. Covinsky, Steven ...> ;Annals of the American Thoracic Society. 2021 Sep 1
4 citations
Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.
Nicholas A. Kolaitis, Ying Gao, Allison Soong, John R. Greenland, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Rupal J. Shah, Mary Ellen Kleinhenz, Patricia P...> ;American Journal of Transplantation. 2021 Feb 1
10 citations
Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.
Daniel T. Dugger, Daniel R Calabrese, Ying Gao, Fred Deiter, Tasha Tsao, J. Maheshwari, Steven R. Hays, Lorriana E. Leard, Mary Ellen Kleinhenz, Rupal J. Shah, Jeffrey...> ;Frontiers in Immunology. 2021 Oct 7
19 citations
Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction.
Carlo J. Iasella, Aki Hoji, Iulia Popescu, Jianxin Wei, Mark E. Snyder, Yingze Zhang, Wei Xu, Vera Iouchmanov, R. Koshy, M. Brown, Monica Fung, Charles Langelier, Eliz...> ;American Journal of Transplantation. 2021 Jun 1
11 citations
Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection
Daniel T. Dugger, Monica Fung, Lorna Zlock, Saharai Caldera, Louis Z. Sharp, Steven R. Hays, Jonathan P. Singer, Lorriana E. Leard, Jefferey A. Golden, Rupal J. Shah, ...> ;Cell Reports. Medicine. 2020 Jul 21
7 citations
Antibiotic adverse reactions in adult cystic fibrosis patients
Karen M. Anstey, Michael Lee, Diana Dawson, Vicki Jue, Jonathan M. Budzik, Michelle Yu, Mary Ellen Kleinhenz, Iris M. Otani> ;The Journal of Allergy and Clinical Immunology. in Practice. 2020 Jul 14
36 citations
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.
Guadalupe Ortiz-Muñoz, Michelle Yu, Emma Lefrançais, Beñat Mallavia, Colin Valet, Jennifer J. Tian, Serena Ranucci, Kristin M. Wang, Zhe Liu, Nicholas Kwaan, Diana Daw...> ;The Journal of Clinical Investigation. 2020 Apr 1
9 citations
Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis
A. Perez, Steven R. Hays, Allison Soong, Ying Gao, John R. Greenland, Lorriana E. Leard, Rupal J. Shah, Jeffrey A. Golden, Jasleen Kukreja, Aida Venado, Mary Ellen Kle...> ;Pediatric Pulmonology. 2020 Apr 1
43 citations
Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.
Beñat Mallavia, Fengchun Liu, Emma Lefrançais, Simon J. Cleary, Nicholas Kwaan, Jennifer J. Tian, Mélia Magnen, David M. Sayah, Allison Soong, Joy Chen, Rajan Saggar, ...> ;American Journal of Respiratory Cell and Molecular Biology. 2020 Feb 28
3 citations
Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients
Nicholas A. Kolaitis, Daniel R Calabrese, Patrick Ahearn, Aida Venado, R. Florez, Huey-Ling Lei, Karolina Isaak, Erik Henricksen, Emily Martinez, Tiffany Chong, Rupal ...> ;American Journal of Health-System Pharmacy. 2019 Dec 2
41 citations
Frailty trajectories in adult lung transplantation: A cohort study.
Aida Venado, Charles E. McCulloch, John R. Greenland, Patricia P. Katz, Allison Soong, Pavan Shrestha, Steven R. Hays, Jeffrey A. Golden, Rupal J. Shah, Lorriana E. Le...> ;The Journal of Heart and Lung Transplantation. 2019 Jul 1
18 citations
Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.
A. Perez, Jonathan P. Singer, Brian S. Schwartz, Peter Chin-Hong, Rupal J. Shah, Mary Ellen Kleinhenz, Ying Gao, Aida Venado, Lorriana E. Leard, Jeffrey A. Golden, Jas...> ;Transplant Infectious Disease. 2019 Jun 1
12 citations
Gene signatures common to allograft rejection are associated with lymphocytic bronchitis
John R. Greenland, Ping Wang, Joshua J. Brotman, Rahul Ahuja, Tiffany Chong, Mary Ellen Kleinhenz, Lorriana E. Leard, Jeffrey A. Golden, Steven R. Hays, Jasleen Kukrej...> ;Clinical Transplantation. 2019 May 1
20 citations
Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation
Nicholas A. Kolaitis, Allison Soong, Pavan Shrestha, Hanjing Zhuo, John Neuhaus, P.P. Katz, John R. Greenland, Jeffrey A. Golden, Lorriana E. Leard, Rupal J. Shah, Ste...> ;The Journal of Thoracic and Cardiovascular Surgery. 2018 Feb 22
3 citations
Severe piperacillin–tazobactam-induced hemolysis in a cystic fibrosis patient
Andrew D. Kerkhoff, Lauren Patrick, Patricia Cornett, Mary Ellen Kleinhenz, Sam Brondfield> ;Clinical Case Reports. 2017 Nov 2
64 citations
Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study.
Jonathan P. Singer, Patricia P. Katz, Allison Soong, Pavan Shrestha, Debbie Huang, Jennifer P. Ho, Malori Mindo, John R. Greenland, Steven R. Hays, Jeffrey A. Golden, ...> ;American Journal of Transplantation. 2017 Jan 3
22 citations
Cystic Fibrosis Transitions of Care: Lessons Learned and Future Directions for Cystic Fibrosis
Megumi J. Okumura, Mary Ellen Kleinhenz> ;Clinics in Chest Medicine. 2016 Mar 1
1 citations
Prolonged Barium-Impaction Ileus in Two Lung Transplant Recipients With Systemic Sclerosis: Case Report.
Sofya Tokman, Steven R. Hays, Lorriana E. Leard, Errol L. Bush, Jasleen Kukreja, Mary Ellen Kleinhenz, Jeffrey A. Golden, Jonathan P. Singer> ;Transplantation Proceedings. 2015 Dec 1
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Hospital Affiliations

UCSF Medical CenterSan Francisco, California