MaryHelenFosterMD

Nephrology • Durham, NC

Professor

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Office
2 Genome Court, Nephrology
Duke University
Durham, NC 27710
Phone+1 919-286-0411
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Education & Training

Tufts Medical CenterFellowship, Nephrology, 1985 - 1989
University of Virginia Medical CenterResidency, Internal Medicine, 1982 - 1985
University of North Carolina at Chapel Hill School of MedicineClass of 1982

Certifications & Licensure

NC State Medical License 2000 - 2024
PA State Medical License 1990 - 2002
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Publications & Presentations

PubMed

Déjà Vu But New: Using T Cells to Deplete B Cells to Treat Lupus.
Rebecca E Sadun, Mary H. Foster> ;American Journal of Kidney Diseases. 2019 Nov 1
11 citations
Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice.
Mary H. Foster, Jeffrey R. Ord, Emma J. Zhao, Anastasiya Birukova, Lanette Fee, Francesca M. Korte, Yohannes G. Asfaw, Victor L. Roggli, Andrew J. Ghio, Robert M. Tigh...> ;Frontiers in Immunology. 2019 Oct 1
2 citations
Emerging immunotherapies for autoimmune kidney disease.
Mary H. Foster, Ord> ;Human Vaccines & Immunotherapeutics. 2019 Jan 16
3 citations
Altered toll-like receptor responsiveness underlies a dominant heritable defect in B cell tolerance in autoimmune New Zealand Black mice.
Amy G. Clark, Elizabeth S. Buckley, Mary H. Foster> ;European Journal of Immunology. 2018 Jan 19
1 citations
A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities.
Amy G. Clark, Inge M. Worni-Schudel, Francesca M. Korte, Mary H. Foster> ;Molecular Immunology. 2017 Nov 1
30 citations
Basement Membranes and Autoimmune Diseases
Mary H. Foster> ;Matrix Biology. 2017 Jan 1
6 citations
Optimizing the Translational Value of Animal Models of Glomerulonephritis: Insights from Recent Murine Prototypes
Mary H. Foster> ;American Journal of Physiology. Renal Physiology. 2016 Sep 1
1 citations
Uncommon structural motifs dominate the antigen binding site in human autoantibodies reactive with basement membrane collagen.
Mary H. Foster, Elizabeth S. Buckley, Benny J. Chen, Kwan-Ki Hwang, Amy G. Clark> ;Molecular Immunology. 2016 Aug 1
5 citations
Recovery of a human natural antibody against the noncollagenous-1 domain of type IV collagen using humanized models
Inge M. Worni-Schudel, Amy G. Clark, Tiffany Chien, Kwan-Ki Hwang, Benny J. Chen, Mary H. Foster> ;Journal of Translational Medicine. 2015 Jun 6
14 citations
Lack of galectin-1 or galectin-3 alters B cell deletion and anergy in an autoantibody transgene model
Amy G. Clark, Melissa L. Weston, Mary H. Foster> ;Glycobiology. 2013 Jul 1
7 citations
Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice.
Amy G. Clark, Qihua Fan, Graham F. Brady, Katherine M. Mackin, Evan D. Coffman, Melissa L. Weston, Mary H. Foster> ;Autoimmunity. 2013 Jan 9
7 citations
Genetic elimination of α3(IV) collagen fails to rescue anti-collagen B cells.
Amy G. Clark, Katherine M. Mackin, Mary H. Foster> ;Immunology Letters. 2011 Dec 30
70 citations
Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis
Steven D. Crowley, Matthew P. Vasievich, Phillip Ruiz, Samantha K. Gould, Kelly K. Parsons, A. Kathy Pazmino, Carie S. Facemire, Benny J. Chen, Hyung Suk Kim, Trinh T....> ;The Journal of Clinical Investigation. 2009 Apr 1
11 citations
Central Tolerance Regulates B Cells Reactive with Goodpasture Antigen α3(IV)NC1 Collagen
Ying Zhang, Susan C. Su, Douglas B. Hecox, Graham F. Brady, Katherine M. Mackin, Amy G. Clark, Mary H. Foster> ;Journal of Immunology. 2008 Nov 1
3 citations
Tracking Differential Gene Expression in MRL/MpJ Versus C57BL/6 Anergic B Cells: Molecular Markers of Autoimmunity
Amy G. Clark, Katherine M. Mackin, Mary H. Foster> ;Biomarker Insights. 2008 Jun 10
12 citations
Multifunctional regulators of cell growth are differentially expressed in anergic murine B cells.
Amy G. Clark, Sihong Chen, Hao Zhang, Graham F. Brady, Erica K. Ungewitter, Joanna K. Bradley, Faustina N. A. Sackey, Mary H. Foster> ;Molecular Immunology. 2007 Feb 1
68 citations
T Cells and B Cells in Lupus Nephritis
Mary H. Foster> ;Seminars in Nephrology. 2007 Jan 1
4 citations
Deconstructing B cell tolerance to basement membranes
Mary H. Foster, Ying Zhang, Amy G. Clark> ;Archivum Immunologiae Et Therapiae Experimentalis. 2006 Jul 10
60 citations
Treatment with a laminin-derived peptide suppresses lupus nephritis.
Howard Amital, Michal Heilweil, Rina Ulmansky, Fanny Szafer, Ruth Bar-Tana, Laurence Morel, Mary H. Foster, Gustavo Mostoslavsky, Dan Eilat, Galina Pizov, Yaakov Napar...> ;Journal of Immunology. 2005 Oct 15
14 citations
κ Editing Rescues Autoreactive B Cells Destined for Deletion in Mice Transgenic for a Dual Specific Anti-Laminin Ig
Graham F. Brady, Kendra L. Congdon, Amy G. Clark, Faustina N. A. Sackey, Earl H. Rudolph, Marko Z. Radic, Mary H. Foster> ;Journal of Immunology. 2004 May 1
4 citations
Taking HAART in HIVAN: will protease inhibitor sparing regimens alter renal outcome?
Mary H. Foster> ;Kidney International. 2004 Mar 1
15 citations
Humoral autoimmunity to basement membrane antigens is regulated in C57BL/6 and MRL/MpJ mice transgenic for anti-laminin Ig receptors.
Earl H. Rudolph, Kendra L. Congdon, Faustina N. A. Sackey, Muriel M. Fitzsimons, Mary H. Foster> ;Journal of Immunology. 2002 Jun 1
3 citations
In vitro and in vivo expression of a nephritogenic Ig heavy chain determinant: pathogenic autoreactivity requires permissive light chains.
Brenda G. Cooperstone, Mohammed M Rahman, Earl H. Rudolph, Mary H. Foster> ;Immunology and Cell Biology. 2001 Jun 1
10 citations
Chronic salicylism resulting in noncardiogenic pulmonary edema requiring hemodialysis
Debbie L. Cohen, Jarrod Post, Anthony A. Ferroggiaro, Jeanmarie Perrone, Mary H. Foster> ;American Journal of Kidney Diseases. 2000 Sep 1
15 citations
Diverse endogenous light chains contribute to basement membrane reactivity in nonautoimmune mice transgenic for an anti-laminin Ig heavy chain.
Margaret Fitzsimons, Howard Y. Chen, Mary H. Foster> ;Immunogenetics. 2000 Jan 1
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Grant Support

Novel Receptor-Ligand Interactions In GlomerulonephritisNational Institute Of Diabetes And Digestive And Kidney Diseases2011
Proximal Determinants Of Nephritogenic AutoimmunityNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2011
Proximal Determinants Of Nephritogenic AutoimmunityNational Institute Of Diabetes And Digestive And Kidney Diseases2008
Proximal Determinants Of Nephritogenic AutoimmunityNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2000
Nephritogenic Antilaminin Ig--A Transgenic ModelNational Institute Of Diabetes And Digestive And Kidney Diseases1995–1998
Genetic Origins Of Nephritogenic AutoantibodiesNational Institute Of Diabetes And Digestive And Kidney Diseases1990–1993
Genetic Origins Of Nephritogenic AutoantibodiesNational Institute Of Diabetes And Digestive And Kidney Diseases1989

Hospital Affiliations

Duke University HospitalDurham, North Carolina
Durham Veterans Affairs Medical CenterDurham, North Carolina

MaryHelenFosterMD

Dr. Foster is on Doximity

Education & Training

Certifications & Licensure

Publications & Presentations

Grant Support

Hospital Affiliations

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