MatlockJeffriesMD
Rheumatology • Oklahoma City, OKOsteoarthritis
Associate Professor, Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation
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Office
825 NE 13th St.
Oklahoma City, OK 73104Phone+1 405-271-7805Fax+1 405-271-8797- Is this information wrong?
Education & Training
University of Oklahoma Health Sciences CenterFellowship, Rheumatology, 2014 - 2016- University of Oklahoma Health Sciences CenterChief Residency, Internal Medicine, 2013 - 2014
- University of Oklahoma Health Sciences CenterResidency, Internal Medicine, 2010 - 2013
- University of Oklahoma College of MedicineClass of 2010
University of OklahomaB.S., Biochemistry; Minors in Spanish, Business, Medical Humanities, 2002 - 2005- Oklahoma State UniversityBachelor's, Biochemistry; Computer Science, 2000 - 2002
Certifications & Licensure
OK State Medical License 2012 - 2025- American Board of Internal Medicine Rheumatology
Awards, Honors, & Recognition
- Lloyd Rader Resident Award for Excellence in Clinical Practice and Medical Research University of Oklahoma Health Sciences Center, 2014
- Winner, Oral Presentation Competition Oklahoma Skeletal Biology Symposium, 2013
- Winner, James F. Hammarsten Award, Best Oral Research Presentation University of Oklahoma Health Sciences Center, 2012
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Publications & Presentations
PubMed
- 2 citationsOA susceptibility in mice is partially mediated by the gut microbiome, is transferrable via microbiome transplantation and is associated with immunophenotype changes.Emmaline Prinz, Leoni Schlupp, Gabby Dyson, Montana Barrett, Aleksander Szymczak, Cassandra Velasco, Vladislav Izda, Christopher M Dunn, Matlock A Jeffries> ;Annals of the Rheumatic Diseases. 2024 Feb 15
- Sex-Linked Discrepancies in C57BL6/J Mouse Osteoarthritis are Associated With the Gut Microbiome and are Transferrable by Microbiome Transplantation.Leoni Schlupp, Emmaline Prinz, Gabriella Dyson, Montana Barrett, Vladislav Izda, Christopher M Dunn, Matlock A Jeffries> ;Arthritis & Rheumatology. 2024 Feb 1
- 3 citationsA Pilot Analysis of Genome-Wide DNA Methylation Patterns in Mouse Cartilage Reveals Overlapping Epigenetic Signatures of Aging and Osteoarthritis.Vladislav Izda, Christopher M Dunn, Emmaline Prinz, Leoni Schlupp, Emily Nguyen, Cassandra Sturdy, Matlock A Jeffries> ;ACR Open Rheumatology. 2022 Dec 1
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Journal Articles
- Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilageJeffries, MA, Donica M, Baker L, Stevenson M, Annand A, Humphrey MB, James JA, Sawalha AH, Arthritis and Rheumatology, 1/30/2014
- Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouseKoelsch K, Webb R, Jeffries MA, Dozmorov M, Frank MB, Guthridge J, James JA, Wren J, Sawalha AH, J. Autoimmunity, 1/1/2013
- Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patientsCoit P, Jeffries M, Altorok N, Dozmorov MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ, Sawalha AH, J Autoimmun, 1/1/2013
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Abstracts/Posters
- Global transcriptomic profiling of osteoarthritic chondrocytesJeffries MA, Multiple Locations, 2014, 1/1/2015
- Epigenome-wide DNA methylation study of osteoarthritic subchondral boneJeffries MA, American College of Rheumatology Annual Meeting, 1/1/2015
- Jeffries MA, American Society of Human Genetics Annual Meeting; American College of Rheumatology Annual Meeting, Boston, 2013; San Diego, 2013, 1/1/2013
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Lectures
- Epigenomics of OsteoarthritisMalaga, Spain, 2014; Sun Valley, ID, 2014 - 1/1/2014
- k-RAS, Epigenetics, and Pancreatic CancerUniversity of Oklahoma - 1/1/2013
- Oklahoma City - 1/1/2013
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Press Mentions
Plenary II Details Data on Biosimilar Switching, Co-Pays, and Other New ResearchNovember 13th, 2022- Summaries of Health Policy Coverage from Major News OrganizationsAugust 11th, 2021
- New Approach Shows Promise for Arthritis ReliefNovember 16th, 2020
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Research History
- Principal InvestigatorMy lab studies epigenetics in osteoarthritis with a particular focus on systemic inflammatory signatures in OA.2016 - Present
Professional Memberships
- Member
Hospital Affiliations
OU HealthOklahoma City, Oklahoma
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