MatthewR.LewinMDPhD

Emergency Medicine • San Francisco, CA

Director, Center for Exploration and Travel Health, California Academy of Sciences

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Office
2570 Bush St
San Francisco, CA 94115
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Education & Training

University of California (San Francisco)/FresnoResidency, Emergency Medicine, 2001 - 2003
Zucker School of Medicine at Hofstra/NorthwellResidency, Emergency Medicine, 2000 - 2001
California Pacific Medical CenterInternship, Internal Medicine, 1999 - 2000
McGovern Medical School at UTHealthClass of 1999

Certifications & Licensure

CA State Medical License 2000 - 2026
NY State Medical License 2010 - 2014
American Board of Emergency Medicine Emergency Medicine

Awards, Honors, & Recognition

Fellow, California Academy of Sciences California Academy of Sciences, 2010

Publications & Presentations

PubMed

3 citations
Neuromuscular Weakness and Paralysis Produced by Snakebite Envenoming: Mechanisms and Proposed Standards for Clinical Assessment.
Philip E Bickler, Michael Abouyannis, Ashish Bhalla, Matthew R Lewin> ;Toxins. 2023 Jan 6
6 citations
Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib.
Guilherme H M Salvador, Êmylle K R Pinto, Paula L Ortolani, Consuelo L Fortes-Dias, Walter L G Cavalcante, Andreimar M Soares, Bruno Lomonte, Matthew R Lewin, Marcos R...> ;Biochimie. 2023 Apr 1
1 citations
Keel venom: Rhabdophis subminiatus (Red-Necked Keelback) venom pathophysiologically affects diverse blood clotting pathways.
Abhinandan Chowdhury, Matthew R Lewin, Rebecca W Carter, Nicholas R Casewell, Bryan G Fry> ;Toxicon. 2022 Oct 30
1 citations
The relative efficacy of chemically diverse small-molecule enzyme-inhibitors against anticoagulant activities of Black Snake (Pseudechis spp.) venoms.
Abhinandan Chowdhury, Nicholas J Youngman, Jiaojiao Liu, Matthew R Lewin, Rebecca W Carter, Bryan G Fry> ;Toxicology Letters. 2022 Aug 1
Envenoming by a Marine Blood Worm ().
Daniela M Durkin, Alison N Young, Kent Khtikian, Zuzana Karjala, Arin L Isenstein, Bryan G Fry, Matthew R Lewin> ;Toxins. 2022 Jul 17
1 citations
Acute Kidney Injury as a Complication of Venomous Snakebite in the United States.
Timothy F Platts-Mills, Matthew R Lewin> ;The American Surgeon. 2022 Jun 1
2 citations
Efficacy and Limitations of Chemically Diverse Small-Molecule Enzyme-Inhibitors against the Synergistic Coagulotoxic Activities ofViper Venoms.
Nicholas J Youngman, Matthew R Lewin, Rebecca Carter, Arno Naude, Bryan G Fry> ;Molecules. 2022 Mar 7
1 citations
Complex regional pain syndrome following southern pacific rattlesnake (C. oreganus helleri) envenoming.
Lawrence McLean House, Matthew R. Lewin, Ramana K. Naidu, Halil Beqaj> ;Clinical Case Reports. 2021 Nov 1
5 citations
The 'Snake song': a pilot study of musical intervention in Eswatini.
Lee T Erickson, Thea Litschka-Koen, Jonathan Pons, Tommaso C. Bulfone, Gideon Bhendile, Shannon M. Fuller, Eoin Harrington, Jerry Harrison, Stephen P. Samuel, Matthew ...> ;Rural and Remote Health. 2020 Jul 6
54 citations
Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms.
José María Gutiérrez, Matthew R. Lewin, David J. Williams, Bruno Lomonte> ;Toxins. 2020 Feb 20
49 citations
Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920).
Guilherme H. M. Salvador, Antoniel A. S. Gomes, Wendy Bryan-Quirós, Julián Fernández, Matthew R. Lewin, José María Gutiérrez, Bruno Lomonte, Marcos R.M. Fontes> ;Scientific Reports. 2019 Nov 20
52 citations
Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Ve...
Matthew R. Lewin, Lyndi L. Gilliam, John Gilliam, Stephen P. Samuel, Tommaso C. Bulfone, Philip E. Bickler, José María Gutiérrez> ;Toxins. 2018 Nov 17
47 citations
Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom.
Matthew R. Lewin, José María Gutiérrez, Stephen P. Samuel, María Herrera, Wendy Bryan-Quirós, Bruno Lomonte, Philip E. Bickler, Tommaso C. Bulfone, David J. Williams> ;Toxins. 2018 Sep 20
49 citations
Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite.
Tommaso C. Bulfone, Stephen P. Samuel, Philip E. Bickler, Matthew R. Lewin> ;Journal of Tropical Medicine. 2018 Jul 30
11 citations
Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies.
Benjamin Herzel, Stephen P. Samuel, Tommaso C. Bulfone, C. Soundara Raj, Matthew R. Lewin, James G. Kahn> ;The American Journal of Tropical Medicine and Hygiene. 2018 May 31
4 citations
Parotid swelling after Russell's viper envenomation: an unusual and poor prognostic sign.
Maanoj N. Sasidaran, Stephen P. Samuel, Soundararaj Chinnaraju, Michael Antonysamy, Tommaso C. Bulfone, Matthew R. Lewin> ;Clinical Case Reports. 2018 Feb 1
134 citations
Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation.
Matthew R. Lewin, Stephen P. Samuel, Janie Merkel, Philip E. Bickler> ;Toxins. 2016 Aug 25
19 citations
Use of von Frey filaments to assess nociceptive sensitization in the hornworm, Manduca sexta.
Marissa Zubia McMackin, Matthew R. Lewin, Dennis R. Tabuena, F. Eric Arreola, Christopher A. Moffatt, Megumi Fuse> ;Journal of Neuroscience Methods. 2016 Jan 15
1 citations
No evidence of neuroprotection? Perhaps not…perhaps so
Matthew R. Lewin, Diana P. Blum> ;Parkinsonism & Related Disorders. 2014 Sep 1
3 citations
Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation.
Matthew R. Lewin, Stephen P. Samuel, David S. Wexler, Philip E. Bickler, Sakthivel Vaiyapuri, Brett D. Mensh> ;Journal of Tropical Medicine. 2014 May 14
1 citations
Subluxation of clinical skills.
Matthew R. Lewin> ;Annals of Emergency Medicine. 2014 Feb 1
6 citations
Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation
Matthew R. Lewin, Philip E. Bickler, Tom Heier, John Feiner, Lance Montauk, Brett D. Mensh> ;Clinical Case Reports. 2013 Oct 1
19 citations
A case and review of noma.
Joseph E. Tonna, Matthew R. Lewin, Brett Mensh> ;Plos Neglected Tropical Diseases. 2010 Dec 21
6 citations
Domicile-related carbon monoxide poisoning in cold months and its relation with climatic factors
Tiekuan Du, Yanping Zhang, Jack S. Wu, Houli Wang, Xu Ji, Tengda Xu, Yi Li, Lingjie Xu, Matthew R. Lewin> ;The American Journal of Emergency Medicine. 2010 Oct 1
6 citations
Diagnostic nuclear medicine in the ED
Behrang Amini, Chirag B. Patel, Matthew R. Lewin, Taegyeong Kim, Ronald E. Fisher> ;The American Journal of Emergency Medicine. 2011 Jan 1
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Press Mentions

Ophirex Receives Wellcome Trust Award to AdvanceMarch 2nd, 2020
Ophirex Licenses Lilly - Shionogi Data for Novel Snakebite Treatment Development ProgramAugust 28th, 2017
Trick of the Trade Epistaxis Control with Tongue BladesJanuary 29th, 2016

Hospital Affiliations

MarinHealth Medical CenterGreenbrae, California
Petaluma Valley HospitalPetaluma, California
Novato Community HospitalNovato, California
San Francisco VA Medical CenterSan Francisco, California