MatthewMeriggioliMD

Neurology • Chicago, IL

Neuromuscular Medicine

Executive Director, Neuroscience Translational Medicine Head, Neuromuscular Disease

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Office
1725 West Harrison Street,
Suite 1106
Chicago, IL 60612
Phone+1 312-942-4500
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Education & Training

Loyola University Medical CenterResidency, Neurology, 1991 - 1994
McGaw Medical Center of Northwestern UniversityInternship, Internal Medicine, 1990 - 1991
Chicago Medical School at Rosalind Franklin University of Medicine and ScienceClass of 1990

Certifications & Licensure

IL State Medical License 1993 - 2023
American Board of Psychiatry and Neurology Neurology

Clinical Trials

A Pilot Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Generalized Myasthenia Gravis Start of enrollment: 2012 Apr 01
Unknown status
Early Phase 1

Publications & Presentations

PubMed

1 citations
Efficacy and safety of iscalimab, a novel anti-CD40 monoclonal antibody, in moderate-to-severe myasthenia gravis: A phase 2 randomized study.
Baltazar GomezMancilla, Matthew N Meriggioli, Angela Genge, Ronenn Roubenoff, Pascal Espié, Cyrielle Dupuy, Nicole Hartmann, Nicole Pezous, Arvind Kinhikar, Mia Tichy,...> ;Journal of Clinical Neuroscience. 2024 Jan 1
105 citations
Five-Year Extension Results of the Phase 1 START Trial of Onasemnogene Abeparvovec in Spinal Muscular Atrophy.
Jerry R. Mendell, Samiah Al-Zaidy, Kelly J. Lehman, Markus McColly, Linda Lowes, Lindsay N. Alfano, Natalie F. Reash, M. Iammarino, Kathleen Church, Aaron Kleyn, Matth...> ;JAMA Neurology. 2021 Jul 1
56 citations
Anti-HMGCR myopathy may resemble limb-girdle muscular dystrophy.
Payam Mohassel, Océane Landon-Cardinal, A. Reghan Foley, Sandra Donkervoort, Katherine Pak, Colleen E. Wahl, Robert T. Shebert, Amy Harper, Pierre R. Fequiere, Matthew...> ;Neurology(R) Neuroimmunology & Neuroinflammation. 2019 Jan 1
24 citations
Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial.
Christopher Grunseich, Ram R. Miller, Therese Swan, David J. Glass, Mohamed El Mouelhi, Mara Fornaro, Olivier Petricoul, Igor Vostiar, Ronenn Roubenoff, Matthew N. Mer...> ;The Lancet. Neurology. 2018 Dec 1
29 citations
Severe Exacerbation of Myasthenia Gravis Associated with Checkpoint Inhibitor Immunotherapy.
Dana S. Cooper, Matthew N. Meriggioli, Philip Bonomi, Rabia Malik> ;Journal of Neuromuscular Diseases. 2017 Jan 1
2 citations
TDP‐43 Proteinopathy: Aggregation and Propagation in the Pathogenesis of Amyotrophic Lateral Sclerosis
Matthew N. Meriggioli, Jeffrey H. Kordower> ;Movement Disorders. 2016 Aug 1
15 citations
Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine
Ted M. Burns, Gordon Smith, Jeffrey A. Allen, Anthony A. Amato, W. David Arnold, Richard J. Barohn, Michael Benatar, Shawn J. Bird, Mark B. Bromberg, Nizar Chahin, Emm...> ;Muscle & Nerve. 2016 Feb 1
49 citations
Current Treatment, Emerging Translational Therapies, and New Therapeutic Targets for Autoimmune Myasthenia Gravis
Jeffrey T. Guptill, Madhu Soni, Matthew N. Meriggioli> ;Neurotherapeutics. 2016 Jan 1
1 citations
The Clinical Spectrum of Necrotizing Autoimmune Myopathy: A Mixed Bag With Blurred Lines
Matthew N. Meriggioli> ;JAMA Neurology. 2015 Sep 1
13 citations
Prospect for Pharmacological Therapies to Treat Skeletal Muscle Dysfunction
Matthew N. Meriggioli, Ronenn Roubenoff> ;Calcified Tissue International. 2015 Mar 1
41 citations
Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis.
Muthusamy Thiruppathi, Jian Rong Sheng, Liang Cheng Li, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Journal of Autoimmunity. 2014 Aug 1
Introduction for myasthenia gravis and related disorders.
Wolfe GI, Meriggioli MN, Ciafaloni E, Ruff RL> ;Ann. N. Y. Acad. Sci.. 2012-12-01
46 citations
Functional defect in regulatory T cells in myasthenia gravis.
Muthusamy Thiruppathi, Julie Rowin, Qin Li Jiang, Jian Rong Sheng, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Annals of the New York Academy of Sciences. 2012 Dec 1
85 citations
Impaired regulatory function in circulating CD4+CD25highCD127low/− T cells in patients with myasthenia gravis
Muthusamy Thiruppathi, Julie Rowin, Balaji B. Ganesh, Jian Rong Sheng, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Clinical Immunology. 2012 Dec 1
Introduction for Myasthenia Gravis and Related Disorders.
Wolfe, G. I.,Meriggioli, M. N.,Ciafaloni, E.,Ruff, R. L.> ;Ann N Y Acad Sci. 2012 Dec
60 citations
Granulocyte macrophage colony-stimulating factor treatment of a patient in myasthenic crisis: Effects on regulatory T cells
Julie Rowin, Muthusamy Thiruppathi, Ebinehita Arhebamen, Jian Rong Sheng, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Muscle & Nerve. 2012 Sep 1
107 citations
Muscle autoantibodies in myasthenia gravis: beyond diagnosis?
Matthew N. Meriggioli, Donald B. Sanders> ;Expert Review of Clinical Immunology. 2012 Jul 1
109 citations
Recommendations for myasthenia gravis clinical trials.
Michael Benatar, Donald B. Sanders, Ted M. Burns, Gary Cutter, Jeffrey T. Guptill, Fulvio Baggi, Henry J. Kaminski, Renato Mantegazza, Matthew N. Meriggioli, Joanne Qu...> ;Muscle & Nerve. 2012 Jun 1
38 citations
GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravis.
Jian Rong Sheng, Thiruppathi Muthusamy, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Journal of Neuroimmunology. 2011 Dec 15
24 citations
Novel and recurrent EMD mutations in patients with Emery–Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot
Charlotte A. Brown, Juergen Scharner, Kevin J. Felice, Matthew N. Meriggioli, Mark A. Tarnopolsky, Matthew Bower, Peter S. Zammit, Jerry R. Mendell, Juliet A. Ellis> ;Journal of Human Genetics. 2011 Aug 1
54 citations
Novel LMNA mutations in patients with Emery‐Dreifuss muscular dystrophy and functional characterization of four LMNA mutations
Juergen Scharner, Charlotte A. Brown, Matthew Bower, Susan T. Iannaccone, Ismail A. Khatri, Diana M. Escolar, Erynn S. Gordon, Kevin J. Felice, Carol A. Crowe, Carla G...> ;Human Mutation. 2011 Feb 1
8 citations
Hashimoto encephalopathy with fulminant myocarditis
Mark Podberezin, Matthew N. Meriggioli, Alberto M. Locante, Andras Voros, Tibor Valyi-Nagy, Andre Kajdacsy-Balla> ;Pathology, Research and Practice. 2010 Oct 15
10 citations
In vivo adsorption of autoantibodies in myasthenia gravis using Nanodisc-incorporated acetylcholine receptor
Jian Rong Sheng, Steve Grimme, Palash Bhattacharya, Michael H. B. Stowell, Michael A. Artinger, Bellur Prabahakar, Matthew N. Meriggioli> ;Experimental Neurology. 2010 Oct 1
30 citations
Nanodisc-Incorporated Hemagglutinin Provides Protective Immunity against Influenza Virus Infection
Palash Bhattacharya, Steve Grimme, Balaji B. Ganesh, Anupama Gopisetty, Jian Rong Sheng, Osvaldo Martinez, Shankar Jayarama, Michael A. Artinger, Matthew N. Meriggioli...> ;Journal of Virology. 2010 Jan 1
10 citations
ACETYLCHOLINE RECEPTOR-α SUBUNIT EXPRESSION IN MYASTHENIA GRAVIS: A ROLE FOR THE AUTOANTIGEN IN PATHOGENESIS?
Jian Rong Sheng, Liang Cheng Li, Bellur S. Prabhakar, Matthew N. Meriggioli> ;Muscle & Nerve. 2009 Aug 1
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Grant Support

12th International Conference On Myasthenia Gravis And Related DisordersNational Institute Of Neurological Disorders And Stroke2011–2012
Immunoregulation Of Experimental Autoimmune Myasthenia GravisNational Institute Of Neurological Disorders And Stroke2007–2011