MatthewMRechlerMD

Internal Medicine • Washington, DC

Physician

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Office
3120 38th St Nw
Washington, DC 20016
Phone+1 202-244-1390
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Summary

Dr. Matthew Rechler, MD is an internist in Washington, District of Columbia. He is currently licensed to practice medicine in Maryland.

Education & Training

Jacobi Medical Center/Albert Einstein College of MedicineResidency, Internal Medicine, 1964 - 1966
Columbia University Vagelos College of Physicians and SurgeonsClass of 1964

Certifications & Licensure

MD State Medical License 1990 - 2021

Publications & Presentations

PubMed

38 citations
IGFBP-3, Hypoxia and TNF-α Inhibit Adiponectin Transcription
Giovanna Zappalà, Matthew M. Rechler> ;Biochemical and Biophysical Research Communications. 2009 May 15
16 citations
An N-terminal fragment of insulin-like growth factor binding protein-3 (IGFBP-3) induces apoptosis in human prostate cancer cells in an IGF-independent manner.
Hanief M Shahjee, Nisan Bhattacharyya, Giovanna Zappalà, Malgorzata Wiench, S. Prakash, Matthew M. Rechler> ;Growth Hormone & IGF Research. 2008 Jun 1
18 citations
Induction of Apoptosis in Human Prostate Cancer Cells by Insulin-Like Growth Factor Binding Protein-3 Does Not Require Binding to Retinoid X Receptor-α
Giovanna Zappalà, Cem Elbi, Joanna Edwards, Julie Gorenstein, Matthew M. Rechler, Nisan Bhattacharyya> ;Endocrinology. 2008 Apr 1
62 citations
Nonsecreted Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) Can Induce Apoptosis in Human Prostate Cancer Cells by IGF-independent Mechanisms without Being Conc...
Nisan Bhattacharyya, Klaus Pechhold, Hanief M Shahjee, Giovanna Zappalà, Cem Elbi, Bruce M. Raaka, Malgorzata Wiench, Jiang Hong, Matthew M. Rechler> ;The Journal of Biological Chemistry. 2006 Aug 25
96 citations
The Coactivator p300 Directly Acetylates the Forkhead Transcription Factor Foxo1 and Stimulates Foxo1-induced Transcription
Valérie Perrot, Matthew M. Rechler> ;Molecular Endocrinology. 2005 Sep 1
55 citations
Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion.
Wen-Chi Tsai, Nisan Bhattacharyya, Li-Ying Han, John A. Hanover, Matthew M. Rechler> ;Endocrinology. 2003 Dec 1
24 citations
Characterization of insulin inhibition of transactivation by a C-terminal fragment of the forkhead transcription factor Foxo1 in rat hepatoma cells.
Valérie Perrot, Matthew M. Rechler> ;The Journal of Biological Chemistry. 2003 Jul 11
132 citations
Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells.
Jiang Hong, George Zhang, Feng Dong, Matthew M. Rechler> ;The Journal of Biological Chemistry. 2002 Mar 22
11 citations
Insulin-like growth factor binding protein-2 mediates the inhibition of DNA synthesis by transforming growth factor-beta in mink lung epithelial cells.
Feng Dong, Hai-Bin Wu, Jiang Hong, Matthew M. Rechler> ;Journal of Cellular Physiology. 2002 Jan 1
22 citations
Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.
Hai-Bin Wu, Amit Kumar, Wen-Chi Tsai, Desmond Mascarenhas, Judy Healey, Matthew M. Rechler> ;Journal of Cellular Biochemistry. 2000 May 1
60 citations
Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR: a mechanism for insulin inhibition of insulin-like...
Minoru Tomizawa, Amit Kumar, Valérie Perrot, Jun Nakae, Domenico Accili, Matthew M. Rechler> ;The Journal of Biological Chemistry. 2000 Mar 10
89 citations
Regulatory Actions of Insulin-like Growth Factor-binding Proteins
Matthew M. Rechler, David R. Clemmons> ;Trends in Endocrinology and Metabolism. 1998 Jul 1
54 citations
Binding of STAT5a and STAT5b to a Single Element Resembling a γ-Interferon-Activated Sequence Mediates the Growth Hormone Induction of the Mouse Acid-Labile Subunit Pr...
Guck T. Ooi, Kelley R. Hurst, Matthew N. Poy, Matthew M. Rechler, Yves R. Boisclair> ;Molecular Endocrinology. 1998 May 1
31 citations
Hepatocyte nuclear factor 1 and the glucocorticoid receptor synergistically activate transcription of the rat insulin-like growth factor binding protein-1 gene.
Dae-Shik Suh, Matthew M. Rechler> ;Molecular Endocrinology. 1997 Nov 1
66 citations
Editorial: Growth Inhibition by Insulin-Like Growth Factor (IGF) Binding Protein-3—What’s IGF Got To Do with It?
Matthew M. Rechler> ;Endocrinology. 1997 Jul 1
86 citations
Growth Hormone Stimulates Transcription of the Gene Encoding the Acid-Labile Subunit (ALS) of the Circulating Insulin-Like Growth Factor-Binding Protein Complex and AL...
Guck T. Ooi, Fredric J. Cohen, Lucy Y.-H. Tseng, Matthew M. Rechler, Yves R. Boisclair> ;Molecular Endocrinology. 1997 Jun 1
7 citations
Insulin-Like Growth Factor-I (IGF-I) Concentration in 150-Kilodalton Complexes Containing Human IGF-Binding Protein-3 (hIGFBP-3) after Intravenous Injection of Adult R...
C Y Lee, Huhehasi Wu, Suh Ds, Matthew M. Rechler> ;Endocrinology. 1997 Apr 1
18 citations
DEXAMETHASONE STIMULATION OF RAT INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1 PROMOTER ACTIVITY INVOLVES MULTIPLE CIS-ELEMENTS
Dae-Shik Suh, Y Zhou, Guck T. Ooi, Matthew M. Rechler> ;Molecular Endocrinology. 1996 Oct 1
40 citations
Heparin inhibition of insulin-like growth factor-binding protein-3 binding to human fibroblasts and rat glioma cells: role of heparan sulfate proteoglycans
Yvonne W.-H. Yang, Masaki Yanagishita, Matthew M. Rechler> ;Endocrinology. 1996 Oct 1
8 citations
Measurement of insulin-like growth factor (IGF)-II binding to purified IGF binding proteins 1–6: comparison of charcoal adsorption and high performance size exclusion ...
Leon A. Bach, Matthew M. Rechler> ;Biochimica Et Biophysica Acta. 1996 Aug 21
43 citations
Proteolysis of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in 150-kilodalton IGFBP complexes by a cation-dependent protease activity in adult rat seru...
C Y Lee, Matthew M. Rechler> ;Endocrinology. 1996 May 1
21 citations
Purified rat acid-labile subunit and recombinant human insulin-like growth factor (IGF)-binding protein-3 can form a 150-kilodalton binary complex in vitro in the abse...
C Y Lee, Matthew M. Rechler> ;Endocrinology. 1995 Nov 1
29 citations
A major portion of the 150-kilodalton insulin-like growth factor-binding protein (IGFBP) complex in adult rat serum contains unoccupied, proteolytically nicked IGFBP-3...
C Y Lee, Matthew M. Rechler> ;Endocrinology. 1995 Feb 1
9 citations
Formation of 150-kDa binary complexes on insulin-like growth factor binding protein-3 and the acid-labile subunit in vitro and in vivo
C. Young Lee, Matthew M. Rechler> ;Progress in Growth Factor Research. 1995 Jan 1
1 citations
Structure and regulation of the ALS gene
Guck T. Ooi, Fredric J. Cohen, Susan Hsieh, Donald Seto, Matthew M. Rechler, Yves R. Boisclair> ;Progress in Growth Factor Research. 1995 Jan 1
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Grant Support

Rxr:Igfbp-3 Binding And The Induction Of Human Prostate Cancer Cell ApoptosisNational Institute Of Diabetes And Digestive And Kidney Diseases2007
Role Of Nuclear IGFBP-3 In The Induction Of Human Prostate Cancer Cell ApoptosisNational Institute Of Diabetes And Digestive And Kidney Diseases2007
Regulation Of Adiponectin Promoter Activity By IGFBP-3National Institute Of Diabetes And Digestive And Kidney Diseases2007
Induction Of Human Prostate Cancer Cell Apoptosis By An IGFBP-3 FragmentNational Institute Of Diabetes And Digestive And Kidney Diseases2007
Insulin-Like Growth Factor Binding ProteinsNational Institute Of Diabetes And Digestive And Kidney Diseases1993–2006
Insulin-Like Growth FactorsNational Institute Of Diabetes And Digestive And Kidney Diseases1990–1992
Insulin-Like Growth Factors--Biosynthesis And ActionNational Institute Of Diabetes And Digestive And Kidney Diseases1988
Insulin-Like Growth Factors (Somatomedins)--Biosynthesis And ActionNational Institute Of Diabetes And Digestive And Kidney Diseases1987
Insulin-Like Growth Factors (Somatomedine)--Biosynthesis And ActionNational Institute Of Diabetes And Digestive And Kidney Diseases1986
Hormones And Receptors--Insulin And Insulin-Like Growth FactorsNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985