Melanie G Cree MD PhD

Director, Multi-disciplinary PCOS clinic

13123 E 16th AveAurora, CO 80045
Phone+1 720-777-1234

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Summary

Dr. Melanie Cree is a pediatric endocrinologist in Denver, CO and is affiliated with Children's Hospital Colorado. She received her medical degree from University of Texas Medical Branch and has been in practice 10 years. She is experienced in precocious puberty, pediatric diabetes, growth disorders, childhood obesity, and pediatric thyroid disease. She specializes in treating teens with type 2 diabetes and polycystic ovary syndrome and is the Director of the multi-disciplinary PCOS clinic at Children's hospital Colorado.

Education & Training

University of ColoradoFellowship, Pediatric Endocrinology, 2011 - 2014
University of ColoradoResidency, Pediatrics, 2008 - 2011
University of Texas Medical Branch School of MedicineClass of 2007
Bryn Mawr CollegeB.A., Biology, Chemistry, 1995 - 1999

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Certifications & Licensure

CO State Medical License 2011 - 2027
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Endocrinology

Awards, Honors, & Recognition

High patient satisfaction award Childrens Hospital Colorado, 2018
Highest Patient Satisfaction Award Children’s Hospital Colorado, 2017
Early Investigators Award Endocrine Society, 2016

Clinical Trials

Liver and Fat Regulation in Overweight Adolescent Girls
COMPLETED
PHASE2, PHASE3
Sleep Timing and Insulin Resistance in Adolescents With Obesity
COMPLETED
Post-Prandial Liver Glucose Metabolism in PCOS Start of enrollment: 2017 Apr 14
COMPLETED

Publications & Presentations

PubMed

From PCOS to PMOS: inclusion of the adolescent voice in setting clinical and research priorities.
Melanie G Cree, Ira Bagga, Phoutdavone Phimphasone-Brady, Sasha Ottey, Alexia S Pena
The Lancet. Child & Adolescent Health. 2026-09-01
Comparing the Independent Effects of Weight Loss or Exercise Training on Skeletal Muscle Lipid Localization and Insulin Sensitivity in Humans.
Simona Zarini, Karin Zemski Berry, Amanda Garfield, Emily Macias, Purevsuren Jambal
Diabetes. 2026-08-18
Testosterone Reference Ranges in Women, Adolescent Girls, and Children: The 2024 PCOS Challenge-CDC Stakeholder Meeting.
Sasha Ottey, Fidelia Pokuah, Melanie Cree, Katherine Sherif, Hubert W Vesper
The Journal of Clinical Endocrinology and Metabolism. 2026-07-14

Journal Articles

Identifying the Critical Gaps in Research on Sex Differences in Metabolism Across the Life Span
Reusch JEB, Kumar TR, Regensteiner JG, Zeitler PS; Conference Participants, Endocrinology, 1/1/2018
Insulin Resistance, Hyperinsulinemia, and Mitochondria Dysfunction in Nonobese Girls With Polycystic Ovarian Syndrome
M. Cree-Green; H. Rahat; B.R. Newcomer; B.C. Bergman; M.S. Brown; G.V. Coe; L. Newnes; Y. Garcia-Reyes; S. Bacon; J.E. Thurston; L. Pyle; A. Scherzinger; K. J. Nadeau, J Endocr Soc, 1/1/2017
Increased Hepatic Steatosis in Obese Adolescents with Hyperandrogenism Relates to Peripheral Insulin Resistance and Markers of De Novo Lipogenesis
M. Cree-Green, B. Bergman, G.L. Coe, L. Newnes, A. Sherzinger, L. Pyle, K.J. Nadeau, Obesity, 1/1/2016

Books/Book Chapters

Pediatric Endocrinology and Inborn Errors of Metabolism
Chapter: Vaginal Bleeding and Menstrual Disorders
B.I. Frohnert, M. Cree-Green, C.A. TerrellEdition 2nd,2017
Aging Men's Health
Chapter: Effect of Androgens on Muscle, Bone, and Hair in Men
Page 83 - 93M. Sheffield-Moore, D. Paddon-Jones, M.G. Cree, D.W. Lackan, and R.J. UrbanEditors: Tan RS.Thieme Medical Publishers, New York, NY2005

Abstracts/Posters

Modeling tissue-specific insulin resistance in obese adolescent girls during an oral glucose tolerance test
C. Diniz Behn , B.C. Bergman, K.J. Nadeau, M. Cree-Green, SIAM, 1/1/2018
Comparing methods for estimating the rate of appearance of exogenous glucose in an oral glucose tolerance test
Kai, M. Cree-Green, B.C. Bergman, K.J. Nadeau, C. Diniz Behn, SIAM, 1/1/2018
Associations between Liver Stiffness by Magnetic Resonance Elastography (MRE), Liver Phospholipids Metabolites and Post-OGTT Metabolism in Obese Adolescent girls with ...
A-M Carreau, T Jensen, Y Garcia-Reyes, H Rahat, D Befroy, BR Newcomer, MS Brown, KJ Nadeau, M Cree-Green, Keystone Symposia on Obesity and NAFLD, 1/1/2018

Lectures

Assessment of metabolic disease in youth
Bethesda, MD - 1/1/2017
Methods of assessing insulin action in humans
Aurora, CO - 1/1/2017
Interactions between sleep and metabolic disease
Wright Sleep Lab, Boulder, CO - 1/1/2017

Other

PhD Thesis Defense
M.G. Cree
UTMB Graduate School, Galveston, TX - 1/1/2005
Biology Thesis Defense
M.G. Cree
Bryn Mawr College, Bryn Mawr, PA - 1/1/1999

Press Mentions

CU Anschutz Researchers Share Innovative Advice on Collaborative Teams in Health ScienceOctober 27th, 2025
Weight Loss Drugs Could Be a Gamechanger for Women with a Common Hormonal DisorderJuly 20th, 2025
GLP-1 Medications Linked to Lower Risk for Type 2 Diabetes in Adolescents with ObesityMay 2nd, 2025

Grant Support

Role of semaglutide in restoring ovulation in youth and adults with polycystic ovary syndromeUNIVERSITY OF COLORADO DENVER2023–2028
The presentation and medical course of PCOS in adolescents across the United StatesUNIVERSITY OF COLORADO DENVER2023–2025
Impact of GLP-1 on Hepatic Fat and Energy Utilization in Obese Girls with Polycystic Ovarian SyndromeUNIVERSITY OF COLORADO DENVER2019–2025