MelanieMalave sanchezMD

Research History

• PI/A pilot, intervention, non-randomized, controlled prospective study to understand the role of estrogen hormonal therapy on accelerated aging, immune activation, and cardiovascular diseaseThe purpose of this study is to evaluate whether administration of exogenous estrogen therapy can reduce cardiovascular disease (CVD) risk and age acceleration in transgender women with and without HIV and who are receiving gender-affirming or feminizing hormone therapy.2021 - 2023
• Sub-I/AGT CS168 Developing a Cure for HIV Disease: Clinical Specimen collection from HIV+ individualsObjective is to get clinical specimens from HIV + individuals to facilitate the development of an FDA approved autologous genetically modified CD4 Tcell preparation2020 - 2022
• Sub-I/Daptomycin Non-susceptibility as a Consequence of Inadequate Source Control in Recurrent, Deep-seated Staphylococcus aureus InfectionsA retrospective chart review of inpatient cases of daptomycin non-susceptible S. aureus (DNSSA) at our institution from 2009-2018. Demographic information, past medical history, microbiologic data, treatment regimens, and clinical outcomes were reviewed.2019 - 2020
• Sub-I/Prevalence of Vitamin D deficiencyRetrospective chart review studying the prevalence of vitamin D deficiency and obstructive sleep apnea in patients undergoing bariatric surgery in Puerto Rico and presented at the Research Symposium of The School of Medicine, UPR Internal Medicine Department2016 - 2017
• Sub-I/R10933-10987 COVID 2069A randomized, double-blind, placebo-controlled trial studying anti spike protein monoclonal antibodies as outpatient treatment for SARS-CoV-2