MeredithChukMDMSc

PubMed

• 2 citations
  Need for aligning the definition and reporting of cytokine release syndrome (CRS) in immuno-oncology clinical trials.
  Mark D Stewart, Bruce McCall, Marcelo Pasquini, Allen S Yang, Carolyn D Britten, Meredith Chuk, R Angelo De Claro, Bindu George, Nicole Gormley, Mary M Horowitz, Eric ...> ;Cytotherapy. 2022 Jul 1
• 31 citations
  FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC.
  Oladimeji Akinboro, Erin Larkins, Lee H Pai-Scherf, Luckson N Mathieu, Yi Ren, Joyce Cheng, Mallorie H Fiero, Wentao Fu, Youwei Bi, Shyam Kalavar, Samina Jafri, Pallav...> ;Clinical Cancer Research. 2022 Jun 1
• 2 citations
  Recommendations for Dose Selection for Adolescent Patients in Relevant Adult Oncology Clinical Trials
  Ruby Leong, Qi Liu, Lingjue Li, Jiang Liu, Yunzhao R. Ren, Peter Lee, Meredith K. Chuk, Gregory H. Reaman, Yaning Wang> ;Clinical Pharmacology and Therapeutics. 2021 Oct 29
• 44 citations
  FDA Approval Summary: Nivolumab Plus Ipilimumab for the Treatment of Patients with Hepatocellular Carcinoma Previously Treated with Sorafenib
  May Tun Saung, Lorraine Pelosof, Sandra Casak, Martha Donoghue, Steven Lemery, Mengdie Yuan, Lisa Rodriguez, Peter Schotland, Meredith K. Chuk, Gina Davis, Kirsten B. ...> ;The Oncologist. 2021 Sep 1
• 5 citations
  Advancing Assessment, Analysis, and Reporting of Safety and Tolerability in Cancer Trials.
  Paul G. Kluetz, Bellinda L King-Kallimanis, Daniel L. Suzman, Elaine Chang, Michael Brave, Chana Weinstock, Vishal Bhatnagar, Julia A. Beaver, Meredith K. Chuk> ;Journal of the National Cancer Institute. 2020 Aug 28
• 8 citations
  Second cancers in adults with acute promyelocytic leukemia treated with or without arsenic trioxide: a SEER-medicare analysis.
  Kelly J. Norsworthy, Armen Avagyan, Steven T. Bird, Yuchen Li, Sandia Akhtar, Jiemin Liao, Michael Wernecke, Albert Deisseroth, Meredith K. Chuk, Thomas E. MaCurdy, Ri...> ;Leukemia. 2020 Jun 9
• Evaluation of Serious Postmarket Safety Signals Within 2 Years of FDA Approval for New Cancer Drugs.
  Janice Kim, Abhilasha Nair, Patricia Keegan, Julia A Beaver, Paul G Kluetz, Richard Pazdur, Meredith Chuk, Gideon M Blumenthal> ;The Oncologist. 2020 Apr 1
• 3 citations
  Reducing Uninformative IND Safety Reports: A List of Serious Adverse Events anticipated to Occur in Patients with Lung Cancer.
  P. Bonomi, Nina Stuccio, C. J. Delgra, Meredith K. Chuk, Alexander Spira, Anne C. Deitz, Gideon M. Blumenthal, Andrea Ferris, Yutao Gong, Jinghua He, Upal Basu Roy, We...> ;Therapeutic Innovation & Regulatory Science. 2020 Mar 26
• 1 citations
  Assessing an ASCO Decision Aid for Improving the Accuracy and Attribution of Serious Adverse Event Reporting From Investigators to Sponsors
  Kathryn Finch Mileham, Caroline Schenkel, Meredith K. Chuk, Andrea D. Buchmeier, Raymond P. Perez, Patricia Hurley, Laura A. Levit, Elizabeth Garrett-Mayer, Courtney D...> ;Journal of Oncology Practice. 2019 Oct 24
• 42 citations
  A phase 1 study of cabozantinib in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1211, a report from the Children...
  Meredith K. Chuk, Brigitte C. Widemann, Charles G. Minard, Xiaowei Liu, Ae Rang Kim, Melanie Brooke Bernhardt, Rachel A. Kudgus, Joel M. Reid, Stephan D. Voss, Susan M...> ;Pediatric Blood & Cancer. 2018 Aug 1
• 93 citations
  Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis.
  Julia A. Beaver, Maitreyee Hazarika, Flora Mulkey, Sirisha Mushti, Huanyu Chen, Kun He, Rajeshwari Sridhara, Kirsten B. Goldberg, Meredith K. Chuk, Dow Chung Chi, Jenn...> ;The Lancet. Oncology. 2018 Feb 1
• 28 citations
  FDA Approval Summary: Eribulin for Patients with Unresectable or Metastatic Liposarcoma Who Have Received a Prior Anthracycline-Containing Regimen.
  Christy L. Osgood, Meredith K. Chuk, Marc R. Theoret, Lan Huang, Kun He, Leah Her, Patricia Keegan, Richard Pazdur> ;Clinical Cancer Research. 2017 Nov 1
• 63 citations
  FDA Approval Summary: Accelerated Approval of Pembrolizumab for Second-Line Treatment of Metastatic Melanoma
  Meredith K. Chuk, Jennie T. Chang, Marc R. Theoret, Emmanuel Sampene, Kun He, Shawna L. Weis, Whitney S. Helms, Runyan Jin, Hongshan Li, Jingyu Yu, Hong Zhao, Liang Zh...> ;Clinical Cancer Research. 2017 Oct 1
• 93 citations
  U.S. FDA Approval Summary: Nivolumab for Treatment of Unresectable or Metastatic Melanoma Following Progression on Ipilimumab
  Maitreyee Hazarika, Meredith K. Chuk, Marc R. Theoret, Sirisha Mushti, Kun He, Shawna L. Weis, Alexander H. Putman, Whitney S. Helms, Xianhua Cao, Hongshan Li, Hong Zh...> ;Clinical Cancer Research. 2017 Jul 15
• 27 citations
  Clinical trial enrollment of adolescents and young adults with sarcoma.
  Lara E. Davis, Katherine A. Janeway, Aaron R. Weiss, Yen-Lin Chen, Thomas J. Scharschmidt, Mark Krailo, Julia L. Glade Bender, Lisa M. Kopp, Shreyaskumar Patel, Gary K...> ;Cancer. 2017 Sep 15
• 38 citations
  Enrolling Adolescents in Disease/Target-Appropriate Adult Oncology Clinical Trials of Investigational Agents
  Meredith K. Chuk, Yeruk Mulugeta, Michelle Roth-Cline, Nitin Mehrotra, Gregory H. Reaman> ;Clinical Cancer Research. 2017 Jan 1
• 2 citations
  Challenges in Opening and Enrolling Patients in Clinical Trials.
  Julie M. Vose, Meredith K. Chuk, Francis J. Giles> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2017 Jan 1
• 4 citations
  Regulatory watch: Evaluating the potential for digital submission of expedited premarket safety reports to the FDA
  Sean Khozin, Meredith K. Chuk, Kim Ts, Suranjan De, Sanjay K. Sahoo, Geoffrey Kim, Richard Pazdur> ;Nature Reviews. Drug Discovery. 2016 Sep 29
• 19 citations
  The Majority of Expedited Investigational New Drug Safety Reports Are Uninformative
  Jonathan P. Jarow, Sandra Casak, Meredith K. Chuk, Lori A. Ehrlich, Sean Khozin> ;Clinical Cancer Research. 2016 May 1
• 23 citations
  Expansion Cohorts in First-in-Human Solid Tumor Oncology Trials
  Marc R. Theoret, Lee Pai-Scherf, Meredith K. Chuk, Tatiana M. Prowell, Sanjeeve Balasubramaniam, Kim Ts, Geoffrey Kim, Paul G. Kluetz, Patricia Keegan, Richard Pazdur> ;Clinical Cancer Research. 2015 Oct 15
• 8 citations
  Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy
  Maya Lodish, Alexandra Gkourogianni, Ethan Bornstein, Ninet Sinaii, Elizabeth Fox, Meredith K. Chuk, Leigh Marcus, Srivandana Akshintala, Frank M. Balis, Brigitte C. W...> ;International Journal of Pediatric Endocrinology. 2015 Feb 16
• 101 citations
  Vandetanib in Children and Adolescents with Multiple Endocrine Neoplasia Type 2B Associated Medullary Thyroid Carcinoma
  Elizabeth Fox, Brigitte C. Widemann, Meredith K. Chuk, Leigh Marcus, Alberta A. Aikin, Patricia Whitcomb, Maria J. Merino, Maya Lodish, Eva Dombi, Seth M. Steinberg, S...> ;Clinical Cancer Research. 2013 Aug 1
• 23 citations
  A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis®, ET-743) in children and adolescents with relapsed or refractory solid tumors
  Meredith K. Chuk, Alberta A. Aikin, Trish Whitcomb, Brigitte C. Widemann, Peter Zannikos, Eliel Bayever, Frank M. Balis, Elizabeth Fox> ;Pediatric Blood & Cancer. 2012 Nov 1
• 11 citations
  111In-Octreotide Scintigraphy for Identification of Metastatic Medullary Thyroid Carcinoma in Children and Adolescents
  Maya Lodish, Urania Dagalakis, Clara C. Chen, Ninet Sinaii, Patricia Whitcomb, Alberta A. Aikin, Eva Dombi, Leigh Marcus, Brigitte C. Widemann, Elizabeth Fox, Meredith...> ;The Journal of Clinical Endocrinology and Metabolism. 2012 Feb 1
• 83 citations
  A Phase 1 Trial and Pharmacokinetic Study of Cediranib, an Orally Bioavailable Pan–Vascular Endothelial Growth Factor Receptor Inhibitor, in Children and Adolescents W...
  Elizabeth Fox, Richard Aplenc, Rochelle Bagatell, Meredith K. Chuk, Eva Dombi, Wendy Goodspeed, Anne Goodwin, Marie Kromplewski, Nalini Jayaprakash, Marcelo Marotti, K...> ;Journal of Clinical Oncology. 2010 Dec 10
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Abstracts/Posters

• Second Cancers in Adults with Acute Promyelocytic Leukemia (APL) Treated with or without Arsenic Trioxide (ATO): A SEER-Medicare Analysis
  Meredith Chuk, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019