MichaelKentCooperMD

PubMed

• Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.
  Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch...> ;Genes Dev.. 2012-08-15
• Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma.
  Xu, B.J., An, Q.A., Srinivasa Gowda, S., Yan, W., Pierce, L.A., Abel, T.W., Rush, S.Z., Cooper, M.K., Ye, F., Shyr, Y., Weaver, K.D., Thompson, R.C.> ;Int J Oncol. 2012 Jun
• Intracranial orthotopic allografting of medulloblastoma cells in immunocompromised mice.
  Huang, X., Sarangi, A., Ketova, T., Litingtung, Y., Cooper, M.K., Chiang, C.> ;J Vis Exp. 2010
• A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
  Cooper, M.K., Wassif, C.A., Krakowiak, P.A., Taipale, J., Gong, R., Kelley, R.I., Porter, F.D., Beachy, P.A.> ;Nat Genet. 2003 Apr
• Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
  Chen, J.K., Taipale, J., Cooper, M.K., Beachy, P.A.> ;Genes Dev. 2002 Nov 1
• Medulloblastoma growth inhibition by hedgehog pathway blockade.
  Berman, D.M., Karhadkar, S.S., Hallahan, A.R., Pritchard, J.I., Eberhart, C.G., Watkins, D.N., Chen, J.K., Cooper, M.K., Taipale, J., Olson, J.M., Beachy, P.A.> ;Science. 2002 Aug 30
• Development of a confirmatory enzyme-linked immunosorbent assay for HIV-1 antibodies.
  Chiang CS, Grove T, Cooper M, Cuan J, Kowalski A, Parcells K, Tsunokawa M, Rosenberg M, Arcuri E, Franklin S> ;Clin. Chem.. 1989-06-01
• Expression and regulation of chicken fibroblast growth factor homologous factor (FHF)-4 during craniofacial morphogenesis.
  Muñoz-Sanjuán, I., Cooper, M. K., Beachy, P. A., Fallon, J. F., Nathans, J.> ;Dev Dyn. 2001 Mar
• Essential role for Sonic hedgehog during hair follicle morphogenesis.
  Chiang, C., Swan, R. Z., Grachtchouk, M., Bolinger, M., Litingtung, Y., Robertson, E. K., Cooper, M. K., Gaffield, W., Westphal, H., Beachy, P. A., Dlugosz, A. A.> ;Dev Biol. 1999 Jan 1
• Patched acts catalytically to suppress the activity of Smoothened.
  Taipale, J., Cooper, M. K., Maiti, T., Beachy, P. A.> ;Nature. 2002 Aug 22
• Teratogen-mediated inhibition of target tissue response to Shh signaling.
  Cooper, M. K., Porter, J. A., Young, K. E., Beachy, P. A.> ;Science. 1998 Jun 5
• Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival.
  Sarangi, A., Valadez, J. G., Rush, S., Abel, T. W., Thompson, R. C., Cooper, M. K.> ;Oncogene. 2009 Oct 01
• Multiple roles of cholesterol in hedgehog protein biogenesis and signaling.
  Beachy, P. A., Cooper, M. K., Young, K. E., von Kessler, D. P., Park, W. J., Hall, T. M., Leahy, D. J., Porter, J. A.> ;Cold Spring Harb Symp Quant Biol. 1997
• Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
  Taipale, J., Chen, J. K., Cooper, M. K., Wang, B., Mann, R. K., Milenkovic, L., Scott, M. P., Beachy, P. A.> ;Nature. 2000 Aug 31
• Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells.
  Ehtesham, M., Sarangi, A., Valadez, J. G., Chanthaphaychith, S., Becher, M. W., Abel, T. W., Thompson, R. C., Cooper, M. K.> ;Oncogene. 2007 Aug 23
• Reappraisal of the role of the DRD3 gene in essential tremor.
  Blair, M. A., Ma, S., Phibbs, F., Fang, J. Y., Cooper, M. K., Davis, T. L., Hedera, P.> ;Parkinsonism Relat Disord. 2008 Aug
• Hedgehog signaling in the murine melanoma microenvironment.
  Geng, L., Cuneo, K. C., Cooper, M. K., Wang, H., Sekhar, K., Fu, A., Hallahan, D. E.> ;Angiogenesis. 2007
• Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor.
  Hedera, P., Phibbs, F. T., Fang, J. Y., Cooper, M. K., Charles, P. D., Davis, T. L.> ;BMC Neurol. 2010
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