MichaelJeffreyGandalMDPhD

PubMed

• Single-cell genomics and regulatory networks for 388 human brains.
  Prashant S Emani, Jason J Liu, Declan Clarke, Matthew Jensen, Jonathan Warrell, Chirag Gupta, Ran Meng, Che Yu Lee, Siwei Xu, Cagatay Dursun, Shaoke Lou, Yuhang Chen, ...> ;Biorxiv. 2024 Mar 30
• 2 citations
  Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain.
  Arjun Bhattacharya, Daniel D Vo, Connor Jops, Minsoo Kim, Cindy Wen, Jonatan L Hervoso, Bogdan Pasaniuc, Michael J Gandal> ;Nature Genetics. 2023 Dec 1
• 8 citations
  Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.
  Daniel F Levey, Marco Galimberti, Joseph D Deak, Frank R Wendt, Arjun Bhattacharya, Dora Koller, Kelly M Harrington, Rachel Quaden, Emma C Johnson, Priya Gupta, Mahant...> ;Nature Genetics. 2023 Dec 1
• 1 citations
  The molecular genetic landscape of human brain size variation.
  Jakob Seidlitz, Travis T Mallard, Jacob W Vogel, Younga H Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M Hernandez, Ayan S Mandal, Konrad Wagstyl, Michael V ...> ;Cell Reports. 2023 Nov 28
• 1 citations
  Comparison of gene expression in living and postmortem human brain.
  Leonardo Collado-Torres, Lambertus Klei, Chunyu Liu, Joel E Kleinman, Thomas M Hyde, Daniel H Geschwind, Michael J Gandal, Bernie Devlin, Daniel R Weinberger> ;Medrxiv. 2023 Nov 9
• 14 citations
  GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
  Anna R Docherty, Niamh Mullins, Allison E Ashley-Koch, Xuejun Qin, Jonathan R I Coleman, Andrey Shabalin, JooEun Kang, Balasz Murnyak, Frank Wendt, Mark Adams, Adrian ...> ;The American Journal of Psychiatry. 2023 Oct 1
• Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
  Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Rude...> ;JAMA psychiatry.
• 409 citations
  Integrative functional genomic analysis of human brain development and neuropsychiatric risks
  Mingfeng Li, Gabriel Santpere, Yuka Imamura Kawasawa, Oleg V. Evgrafov, Forrest O. Gulden, Sirisha Pochareddy, Susan M. Sunkin, Zhen Li, Yurae Shin, Ying Zhu, André M....> ;Science. 2018 Dec 14
• Transcriptome and epigenome landscape of human cortical development modeled in organoids.
  Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM, PsychENCODE Consortium, Gerstein M, Crawford GE, Se...> ;Science (New York, N.Y.).
• 6 citations
  Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes.
  Varun Warrier, Eva-Maria Stauffer, Qin Qin Huang, Emilie M Wigdor, Eric A W Slob, Jakob Seidlitz, Lisa Ronan, Sofie L Valk, Travis T Mallard, Andrew D Grotzinger, Rafa...> ;Nature Genetics. 2023 Sep 1
• 2 citations
  150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.
  Yeda Wu, Slavina B Goleva, Lindsay B Breidenbach, Minsoo Kim, Stuart MacGregor, Michael J Gandal, Lea K Davis, Naomi R Wray> ;Cell Genomics. 2023 Jul 12
• 5 citations
  Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period.
  Nazim Kourdougli, Anand Suresh, Benjamin Liu, Pablo Juarez, Ashley Lin, David T Chung, Anette Graven Sams, Michael J Gandal, Verónica Martínez-Cerdeño, Dean V Buonoman...> ;Neuron. 2023 Sep 20
• 5 citations
  Interactions between the lipidome and genetic and environmental factors in autism.
  Chloe X Yap, Anjali K Henders, Gail A Alvares, Corey Giles, Kevin Huynh, Anh Nguyen, Leanne Wallace, Tiana McLaren, Yuanhao Yang, Leanna M Hernandez, Michael J Gandal,...> ;Nature Medicine. 2023 Apr 1
• 2 citations
  Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms.
  Ashok Patowary, Pan Zhang, Connor Jops, Celine K Vuong, Xinzhu Ge, Kangcheng Hou, Minsoo Kim, Naihua Gong, Michael Margolis, Daniel Vo, Xusheng Wang, Chunyu Liu, Bogda...> ;Biorxiv. 2023 Oct 11
• 4 citations
  Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth.
  Leanna M Hernandez, Minsoo Kim, Pan Zhang, Richard A I Bethlehem, Gil Hoftman, Robert Loughnan, Diana Smith, Susan Y Bookheimer, Chun Chieh Fan, Carrie E Bearden, Wesl...> ;Genome Biology. 2023 Mar 7
• 4 citations
  Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex.
  Pan Zhang, Alicja Omanska, Bradley P Ander, Michael J Gandal, Boryana Stamova, Cynthia M Schumann> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Mar 7
• 4 citations
  Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.
  Cindy Wen, Michael Margolis, Rujia Dai, Pan Zhang, Pawel F Przytycki, Daniel D Vo, Arjun Bhattacharya, Nana Matoba, Chuan Jiao, Minsoo Kim, Ellen Tsai, Celine Hoh, Nil...> ;Medrxiv. 2023 Mar 6
• 1 citations
  No Increased Detection of Nucleic Acids of CNS-related Viruses in the Brains of Patients with Schizophrenia, Bipolar Disorder, and Autism Spectrum Disorder.
  Shishi Min, Michael J Gandal, Richard F Kopp, Chunyu Liu, Chao Chen> ;Schizophrenia Bulletin. 2023 May 3
• 2 citations
  Decoupling Sleep and Brain Size in Childhood: An Investigation of Genetic Covariation in the Adolescent Brain Cognitive Development Study.
  Leanna M Hernandez, Minsoo Kim, Cristian Hernandez, Wesley Thompson, Chun Chieh Fan, Adriana Galván, Mirella Dapretto, Susan Y Bookheimer, Andrew Fuligni, Michael J Ga...> ;Biological Psychiatry Global Open Science. 2023 Jan 1
• 3 citations
  GeneticsMakie.jl: a versatile and scalable toolkit for visualizing locus-level genetic and genomic data.
  Minsoo Kim, Daniel D Vo, Michi E Kumagai, Connor T Jops, Michael J Gandal> ;Bioinformatics. 2023 Jan 1
• 46 citations
  Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
  Michael J Gandal, Jillian R Haney, Brie Wamsley, Chloe X Yap, Sepideh Parhami, Prashant S Emani, Nathan Chang, George T Chen, Gil D Hoftman, Diego de Alba, Gokul Ramas...> ;Nature. 2022 Nov 1
• 6 citations
  TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.
  Momoko Watanabe, Jessie E Buth, Jillian R Haney, Neda Vishlaghi, Felix Turcios, Lubayna S Elahi, Wen Gu, Caroline A Pearson, Arinnae Kurdian, Natella V Baliaouri, Aman...> ;Stem Cell Reports. 2022 Oct 11
• 1 citations
  A Critical Appraisal of Imaging Transcriptomics.
  Ayan S Mandal, Michael Gandal, Jakob Seidlitz, Aaron Alexander-Bloch> ;Biological Psychiatry Global Open Science. 2022 Oct 1
• 8 citations
  White matter microstructure shows sex differences in late childhood: Evidence from 6797 children.
  Katherine E Lawrence, Zvart Abaryan, Emily Laltoo, Leanna M Hernandez, Michael J Gandal, James T McCracken, Paul M Thompson> ;Human Brain Mapping. 2023 Feb 1
• 4 citations
  Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.
  Gabriel E Hoffman, Andrew E Jaffe, Michael J Gandal, Leonardo Collado-Torres, Solveig K Sieberts, Bernie Devlin, Daniel H Geschwind, Daniel R Weinberger, Panos Roussos> ;Molecular Psychiatry. 2023 Feb 1
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Journal Articles

• Discovery of the First Genome-Wide Significant Risk Loci for Attention deficit/hyperactivity Disorder  
  Henry R Kranzler, Hakon Hakonarson, Michael Gandal, Elise B Robinson, Nature
• Integrative Network Analysis Reveals Biological Pathways Associated with Williams Syndrome  
  Michael J Gandal, Daniel H Geschwind, Journal of Child Psychology and Psychiatry
• Author Correction: Genome-Wide Changes in lncRNA, Splicing, and Regional Gene Expression Patterns in Autism  
  Daniel H Geschwind, Michael J Gandal, Nature