MichaelJohnGarciaMD

PubMed

• Quantitative expression profiling in mouse spinal cord reveals changing relationships among channel and receptor mRNA levels across postnatal maturation.
  Garcia, V. B.,Garcia, M. L.,Schulz, D. J.> ;Neuroscience. 2014 Jul 22
• Axonal Transport: How High Microtubule Density Can Compensate for Boundary Effects in Small-Caliber Axons.
  Wortman, J. C.,Shrestha, U. M.,Barry, D. M.,Garcia, M. L.,Gross, S. P.,Yu, C. C.> ;Biophys. J.. 2014 Feb 25
• Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy.
  Cobb, M. S.,Rose, F. F.,Rindt, H.,Glascock, J. J.,Shababi, M.,Miller, M. R.,Osman, E. Y.,Yen, P. F.,Garcia, M. L.,Martin, B. R.,Wetz, M. J.,Mazzasette, C.,Feng, Z.,Ko,...> ;Hum. Mol. Genet.. 2013 May 1
• 25 citations
  Transgenic inactivation of murine myostatin does not decrease the severity of disease in a model of Spinal Muscular Atrophy.
  Hansjörg Rindt, Desire M. Buckley, Spencer M. Vale, Megan M. Krogman, Ferrill F. Rose, Michael L. Garcia, Christian L. Lorson> ;Neuromuscular Disorders. 2012 Mar 1
• Expressing hNF-LE397K results in abnormal gaiting in a transgenic model of CMT2E.
  Dale, J.M., Villalon, E., Shannon, S.G., Barry, D.M., Markey, R.M., Garcia, V.B., Garcia, M.L.> ;Genes Brain Behav. 2012 Apr
• The spinal muscular atrophy mouse model, SMA??7, displays altered axonal transport without global neurofilament alterations.
  Dale, J.M., Shen, H., Barry, D.M., Garcia, V.B., Rose, F.F., Lorson, C.L., Garcia, M.L.> ;Acta Neuropathol. 2011 Sep
• Muscle pathology without severe nerve pathology in a new mouse model of Charcot-Marie-Tooth disease type 2E.
  Shen, H., Barry, D.M., Dale, J.M., Garcia, V.B., Calcutt, N.A., Garcia, M.L.> ;Hum Mol Genet. 2011 Jul 1
• Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.
  Garcia, M.L., Rao, M.V., Fujimoto, J., Garcia, V.B., Shah, S.B., Crum, J., Gotow, T., Uchiyama, Y., Ellisman, M., Calcutt, N.A., Cleveland, D.W.> ;J Neurosci. 2009-02-04
• The Wallerian degeneration slow (Wld(s)) gene does not attenuate disease in a mouse model of spinal muscular atrophy.
  Rose, F.F., Meehan, P.W., Coady, T.H., Garcia, V.B., Garcia, M.L., Lorson, C.L.> ;Biochem Biophys Res Commun. 2008 Oct 10
• Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.
  Yamanaka, K., Boillee, S., Roberts, E.A., Garcia, M.L., McAlonis-Downes, M., Mikse, O.R., Cleveland, D.W., Goldstein, L.B.> ;Proc Natl Acad Sci U S A. 2008 May 27
• New movements in neurofilament transport, turnover and disease.
  Barry, D.M., Millecamps, S., Julien, J., Garcia, M.L.> ;Exp Cell Res. 2007 Jun 10
• Mutations in neurofilament genes are not a significant primary cause of non-SOD1-mediated amyotrophic lateral sclerosis.
  Garcia, M.L., Singleton, A.B., Hernandez, D., Ward, C.M., Evey, C., Sapp, P.A., Hardy, J., Brown, R.H., Cleveland, D.W.> ;Neurobiol Dis. 2006 Jan
• Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.
  Lobsiger, C. S.,Garcia, M. L.,Ward, C. M.,Cleveland, D. W.> ;Proc Natl Acad Sci U S A. 2005 Jul 19
• The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease.
  Vande Velde, C., Garcia, M.L., Yin, X., Trapp, B.D., Cleveland, D.W.> ;Neuromolecular Med. 2004
• NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.
  Garcia, M.L., Lobsiger, C.S., Shah, S.B., Deerinck, T.J., Crum, J., Young, D., Ward, C.M., Crawford, T.O., Gotow, T., Uchiyama, Y., Ellisman, M.H., Calcutt, N.A., Clev...> ;J Cell Biol. 2003 Dec 8
• Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow a...
  Rao, M.V., Garcia, M.L., Miyazaki, Y., Gotow, T., Yuan, A., Mattina, S., Ward, C.M., Calcutt, N.A., Uchiyama, Y., Nixon, R.A., Cleveland, D.W.> ;J Cell Biol. 2002 Aug 19
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