Michael Gilbert Goggins MD

PubMed

• Impact of race, sex and age on the probability of pancreatic cancer among patients with newly diagnosed diabetes in a claims-based cohort.
  Elham Afghani, Bryan Lau, Laura K Becker, Michael Goggins, Alison P Klein
  BMJ Open. 2025-05-26
• Reply to the Letter to the Editor regarding "Early detection of pancreatic cancer: Study design and analytical considerations in biomarker discovery and early phase va...
  Douglas M Mahoney, Lynette M Smith, Qiao-Li Wang, Grant Izmirlian, Gregory A Coté
  Pancreatology. 2025-05-01
• A Mixed-Methods Approach to Assessing Barriers and Facilitators to Cancer Genetics Care in Black and Latino/a Individuals Impacted by Pancreatic Cancer: The Racial/eth...
  Nicolette Juliana Rodriguez, Tara B Coffin, Andrew J Ward, Juan Felipe Rodriguez, Chinedu Ukaegbu
  Digestive Diseases and Sciences. 2025-04-27

Journal Articles

• Pancreatic Cancer Arising in the Remnant Pancreas Is Not Always a Relapse of the Preceding Primary  
  John L Cameron, Christopher L Wolfgang, Jin He, Matthew J Weiss, Ralph H Hruban, Michael Goggins, Nature
• Single‐Cell Sequencing Defines Genetic Heterogeneity in Pancreatic Cancer Precursor Lesions  
  Kevin Waters, Jin He, Christopher L Wolfgang, Ralph H Hruban, Michael G Goggins, Matthew J Weiss, Justin Poling, The Journal of Pathology
• Primordial Germ Cells as a Potential Shared Cell of Origin for Mucinous Cystic Neoplasms of the Pancreas and Mucinous Ovarian Tumors  
  Leona A Doyle, Daniel W Cramer, Michael Goggins, Ronny Drapkin, Jason L Hornick, Kevin M Elias, Michael Birrer, Michelle S Hirsch, The Journal of Pathology
• Blood Type as a Predictor of High-Grade Dysplasia and Associated Malignancy in Patients with Intraductal Papillary Mucinous Neoplasms  
  Martin A Makary, Michael Goggins, James Griffin, Katherine E Poruk, Jin He, Matthew J Weiss, John L Cameron, Christopher L Wolfgang, Journal of gastrointestinal surgery
• Long interspersed element-1 protein expression is a hallmark of many human cancers  
  Rodic N, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA, Maitra A, Torbenson MS, Goggins M, Shih Ie M, Duffield AS, Montgomery EA, gabrielson ..., Am J Pathol, 1/1/2014
• Role of a Multidisciplinary Clinic in the Management of Patients with Pancreatic Cysts: A Single-Center Cohort Study  
  Lennon AM, Manos LL, Hruban RH, Ali SZ, Fishman EK, Kamel IR, Raman SP, Zaheer A, Hutfless S, Salamone A, Kiswani V, Ahuja N, Makary MA, Weiss MJ, Hirose K, Goggins M,..., Ann Surg Oncol, 1/1/2014
• A systematic review of solid-pseudopapillary neoplasms: are these rare lesions?  
  Law JK, Ahmed A, Singh VK, Akshintala VS, Olson MT, Raman SP, Ali SZ, Fishman EK, Kamel I, Canto MI, Dal Molin M, Moran RA, Khashab MA, Ahuja N, Goggins M, Hruban RH, ..., Pancreas, 1/1/2014
• Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis  
  Kim H, Saka B, Knight S, Borges M, Childs E, Klein AP, Wolfgang CL, Herman JM, Adsay V, Hruban RH, Goggins M, Clin Cancer Res, 1/1/2014
• The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?  
  Lennon AM, Wolfgang CL, Canto MI, Klein AP, Herman JM, Goggins M, Fishman EK, Kamel I, Weiss MJ, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Cancer Res, 1/1/2014
• International Consensus Recommendations on the Management of Patients with Increased Risk for Familial Pancreatic Cancer (The Cancer of the Pancreas Screening (CAPS) C...  
  Canto MI, Harinck F, Hruban RH, Offerhaus GJ, Poley JW, Fockens P, Kamel I, Nio Y, Schulick R, Bassi C, Kluijt I, Goggins M, Bruno M, gut, 1/1/2013
• Mutant TP53 in Duodenal Samples of Pancreatic Juice from Patients with Pancreatic Cancer or High-grade Dysplasia  
  Kanda M, Sadakari Y, Borges M, Topazian M, Farrell J, Syngal S, Lee J, Kamel I, Lennon AM, Knight S, Fujiwara S, Hruban RH, Canto MI, Goggins M, Clin gastroenterol Hepatol, 1/1/2013
• Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4  
  Leenders M, Bhattacharjee S, Vineis P, Stevens V, Bueno-de-Mesquita HB, Shu XO, Amundadottir L, gross M, Tobias gS, Wactawski-Wende J, Arslan AA, Duell EJ, Fuchs CS, g..., Cancer Causes Control, 1/1/2013
• Clinicopathological Correlates of Activating gNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas  
  Dal Molin M, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini g, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruba..., Ann Surg Oncol, 1/1/2013
• Novel methylation biomarker panel for the early detection of pancreatic cancer  
  Yi JM, guzzetta AA, Bailey VJ, Downing SR, Van Neste L, Chiappinelli KB, Keeley BP, Stark A, Herrera A, Wolfgang C, Pappou EP, Iacobuzio-Donahue CA, Goggins MG, Herman..., Clinical Cancer Research, 1/1/2013
• MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls  
  Li A, Yu J, Kim H, Wolfgang CL, Canto MI, Hruban RH, Goggins M, Clinical Cancer Research, 1/1/2013
• Novel methylation biomarker panel for the early detection of pancreatic cancer  
  Yi JM, guzzetta AA, Bailey VJ, Downing SR, Van Neste L, Chiappinelli KB, Keeley BP, Stark A, Herrera A, Wolfgang C, Pappou EP, Iacobuzio-Donahue CA, Goggins MG, Herman..., Clin Cancer Res, 1/1/2013
• S100A4 expression is a prognostic indicator in small intestine adenocarcinoma  
  Roh J, Knight S, Chung JY, Eo SH, Goggins M, Kim J, Cho H, Yu E, Hong SM, J Clin Pathol, 1/1/2013
• Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop  
  Andersen DK, Andren-Sandberg A, Duell EJ, Goggins M, Korc M, Petersen gM, Smith JP, Whitcomb DC, Pancreas, 1/1/2013
• The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma  
  Perez-Mancera PA, Rust Ag, van der Weyden L, Kristiansen g, Li A, Sarver AL, Silverstein KA, grutzmann R, Aust D, Rummele P, Knosel T, Herd C, Stemple DL, Kettleboroug..., Nature, 1/1/2012
• Pathway Analysis of Genome-wide Association Study Data Highlights Pancreatic Development genes as Susceptibility Factors for Pancreatic Cancer  
  Li D, Duell EJ, Yu K, Risch HA, Olson SH, Kooperberg C, Wolpin BM, Jiao L, Dong X, Wheeler B, Arslan AA, Bueno-de-Mesquita HB, Fuchs CS, gallinger S, gross M, Hartge P..., Carcinogenesis, 1/1/2012
• Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia  
  Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B, Goggins M, gastroenterology, 1/1/2012
• Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types  
  Jones S, Li M, Parsons DW, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A..., Hum Mutat, 1/1/2012
• Detectable clonal mosaicism and its relationship to aging and cancer  
  Jacobs KB, Yeager M, Zhou W, Wacholder S, Wang Z, Rodriguez-Santiago B, Hutchinson A, Deng X, Liu C, Horner MJ, Cullen M, Epstein Cg, Burdett L, Dean MC, Chatterjee N,..., Nat genet, 1/1/2012
• Genome-wide Cpg island profiling of intraductal papillary mucinous neoplasms of the pancreas  
  Hong SM, Omura N, Vincent A, Li A, Knight S, Yu J, Hruban RH, Goggins M, Clin Cancer Res, 1/1/2012
• Vascular invasion in infiltrating ductal adenocarcinoma of the pancreas can mimic pancreatic intraepithelial neoplasia: a histopathologic study of 209 cases  
  Hong SM, Goggins M, Wolfgang CL, Schulick RD, Edil BH, Cameron JL, Handra-Luca A, Herman JM, Hruban RH, Am J Surg Pathol, 1/1/2012
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Books/Book Chapters

• Pancreatic Cancer, Methods in Molecular Medicine 
  Chapter: DNA methylation analysis in human cancer. 
  Page 131 - 156Eileen O'Sullivan, Michael GogginsEditors: gloria Su.Methods Mol BiolEdition 2nd,2013
• Hopkins Internal Medicine Board Review 
  Chapter: Disorders of the Small and Large Intestine. 
  Lennon AM, Goggins MEditors: Bimal Asher, Redonda Miller, Stephen Sisson.2011
• The Handbook of Pancreatic cancer 
  Chapter: The Development of Novel Biomarkers of Pancreatic Neoplasia. 
  Goggins MEditors: Neoptomolos, Urrutia, Abbruzzese, Buchler.Springer2009
• The Handbook of Pancreatic cancer 
  Chapter: Diagnostic and Therapeutic Response Markers. 
  Lennon AM, Goggins MEditors: Neoptomolos, Urrutia, Abbruzzese, Buchler.Springer2009
• Reelin 
  Chapter: Reelin and Pancreatic cancer. 
  Kimberly Walter and M Goggins, Dr. Fatemi2008
• Pancreatic Cancer 
  Chapter: Molecular Diagnosis of Pancreatic Cancer. 
  Goggins MEditors: von Hoff D, Evans D, Hruban R.Jones and Bartlett Publishers, Sudbury, MAEdition 1st,2005
• The principles and Practice of gastrointestinal Oncology 
  Chapter: The molecular biology of cholangiocarcinoma and gall Bladder carcinomas. 
  Goggins MEditors: Abbruzzese J, Evans D, Willett, Hamilton SR.Oxford University Press, New YorkEdition 1st,2004
• Advanced Therapy of gastroenterology and Liver Disease 
  Chapter: Neoplastic Cysts and Other Precancerous Lesions of the Pancreas. 
  Hruban RH, Goggins M, Yeo CJEditors: Theodore Bayless and Anna Mae Diehl.Edition 5th,2004
• Cancer: Principles and Practice of Oncology 
  Chapter: Cancer of the Pancreas. 
  Yeo TP, Hruban RH, Kern SE, Iacobuzio-Donahue CA, Maitra A, Goggins M, Canto MI, Abrams RA, Laheru D, Jaffee EM, Hidalgo M, Yeo CJEditors: DeVita VT, Hellman S, Rosenberg, S.Lippincott Williams &Wilkins, Philadelphia, PAEdition 7th,2004
• The Cancer Handbook 
  Chapter: Systemic Oncology of the pancreas. 
  Goggins M, Wilentz R, Hruban RHEditors: Malcolm Alison.MacMillan Press, London2002
• Cancer Precursors; Epidemiology, Detection and Prevention 
  Chapter: Pancreatic cancer epidemiology, detection and prevention. 
  Goggins M, Kern SE, Hruban RHEditors: L Franco and Thomas E Rohan.Springer-Verlag, New York, Inc.2002
• Principles and Practice of gastrointestinal Oncology 
  Chapter: Molecular genetics of Pancreatic Cancer. 
  Goggins MEditors: Kelsen DP, Daly JM, Kern SE, Levin B, Tepper J.Lippincott, Williams and Wilkins, Co.2001
• The Johns Hopkins Internal Medicine Board Review 
  Chapter: Disorders of the Small and Large Intestine. 
  M. GogginsEditors: Redonda Miller, Stephen Sisson, Bimal Asher.Mosby PublishersEdition 2nd,
• Molecular genetics of Pancreatic Cancer 
  Chapter: Epigenetic alterations of Pancreatic Cancer. 
  Michael Ayars, Michael GogginsEditors: Simeone, Maitra.Springer US
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Lectures

• Improving the early detection of pancreatic cancer. 
  Johns Hopkins Oncology Center - 2/19/2014
• The potential clinical utility of markers of pancreatic neoplasia. 
  Yale, New Haven, CT - 11/22/2013
• "The potential clinical utility of markers of pancreatic neoplasia", Visiting Professor 
  University of Pennsylvania, Philadelphia - 11/13/2013
• "Pancreatic cancer screening", Session Discussant 
  10/17/2013
• Grand Rounds: "The potential clinical utility of markers of pancreatic neoplasia" 
  University of Nebraska Medical Center Cancer Center, Omaha, NE - 8/13/2013
• "Pancreatitis, pancreatic cancer and diabetes." 
  NIH, Bethesda, MD - 6/12/2013
• Update on Pancreatic Cancer Screening. 
  University of Pennsylvania - 4/16/2013
• "Markers of pancreatic neoplasia and their clinical utility." Visiting Professor 
  Nagoya University, Japan - 2/15/2013
• Screening for pancreatic cancer in high risk individuals. 
  Boston - 10/27/2012
• Pancreatic cancer screening. 
  Boston - 10/26/2012
• Screening for pancreatic cancer: Current status and future plans. 
  NCI, Bethesda - 10/24/2012
• "Pancreatic Neuroendocrine tumors What's new in 2012" 
  Johns Hopkins University, Baltimore, MD - 10/1/2012
• Using molecular markers to improve pancreatic screening. 
  Bonn, germany - 7/8/2012
• Pancreatic cysts. 
  Bonn, germany - 7/7/2012
• Non-coding alterations and the development of pancreatic neoplasia. 
  Bayview Medical Center, Baltimore - 12/8/2011
• Genetic profiles of precancerous pancreatic lesions. 
  Boston, MA - 10/23/2011
• Update on pancreatic cysts. 
  Dulles, VA - 9/15/2011
• Translational Science : Current And Future Applications In gastrointestinal Cancer. 
  TCD, Dublin - 9/8/2011
• Molecular genetics of pancreatic cancer. 
  6/17/2011
• The Early Detection of Pancreatic Cancer and its precursors. 
  3/1/2011
• The molecular biology and progression of pancreatic ductal adenocarcinoma. 
  Memorial Sloan Kettering CC, NYC - 10/2/2010
• Pancreatic cancer, the Next 10 years. 
  Memorial Sloan Kettering CC, NYC - 10/2/2010
• Recent developments in our understanding of pancreatic cancer etiology and management. 
  Fukuoka, Japan - 7/13/2010
• Molecular profiles of pancreatic neoplasia and their clinical utility. 
  Nagoya University, Japan - 7/9/2010
• "Screening for early pancreatic cancer: when, in whom and how?" 
  Cork University, Ireland - 10/2/2009
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Other

• Absence of ALK-5 mutations in breast cancer cell lines. 
  Goggins M, Shekher M, Turnacioglu K, Yeo CJ, Hruban RH, Kern SE, NOgO
  1/1/1998
• Absence of Beta-catenin mutations in patients with pancreatic cancer. ( On-Line Publication) 
  Goggins M, Hilgers W, Hruban RH, Kern SE, NOgO
  1/1/1997
• Absence of Beta-catenin mutations in patients with breast cancer. 
  Goggins M, Hilgers W, Hruban RH, Kern SE, NOgO
  1/1/1997
• Normal SMAD2 gene in pancreatic cancer. 
  gJ Riggins; S Thiagalingam; Goggins M; SE Kern; KW Kinzler; B Vogelstein, NOgO
  1/1/1997
• National Academy of Clinical Biochemistry (NACB) guidelines for the Use of Tumor Markers in Pancreatic Ductal Adenocarcinoma. 
  Goggins M, Koopmann J, Yang D, Canto MI, Hruban RH
  http://www.nacb.org/lmpg/tumor/chp3i_pancreatic.pdf
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