MichaelLeonardHowellMD

PubMed

• Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion.
  Sundaramoorthy S, Vázquez-Novelle MD, Lekomtsev S, Howell M, Petronczki M> ;EMBO J.. 2014-11-18
• Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.
  McKnight NC, Jefferies HBJ, Alemu EA, Saunders RE, Howell M, Johansen T, Tooze SA> ;EMBO J.. 2012-04-18
• Glioblastoma motility occurs in the absence of actin polymer.
  Panopoulos A, Howell M, Fotedar R, Margolis RL> ;Mol. Biol. Cell. 2011-07-01
• 59 citations
  Two‐pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration
  Sang Sun Yoon, Ahmet C. Karabulut, John D. Lipscomb, Robert F. Hennigan, Sergei V. Lymar, Stephanie L. Groce, Andrew B. Herr, Michael L. Howell, Patricia J. Kiley, Mic...> ;The EMBO Journal. 2007 Aug 8
• 35 citations
  A new method to remove hybridization bias for interspecies comparison of global gene expression profiles uncovers an association between mRNA sequence divergence and d...
  Maureen A. Sartor, Aaron M. Zorn, Jennifer A. Schwanekamp, Danielle Halbleib, Saikumar Karyala, Michael L. Howell, Gary E. Dean, Mario Medvedovic, Craig R. Tomlinson> ;Nucleic Acids Research. 2006 Jan 1
• Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription.
  Howell M, Borchers C, Milgram SL> ;J. Biol. Chem.. 2004-06-18
• Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability.
  Maurice D, Pierreux CE, Howell M, Wilentz RE, Owen MJ, Hill CS> ;J. Biol. Chem.. 2001-11-16
• 46 citations
  AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide.
  Michael L. Howell, Eyad Alsabbagh, Ju-Fang Ma, Urs A. Ochsner, Martin G. Klotz, Terry J. Beveridge, Kenneth M. Blumenthal, Eric C. Niederhoffer, Randall E. Morris, Dav...> ;Journal of Bacteriology. 2000 Aug 15
• 82 citations
  A Protease-Resistant Catalase, KatA, Released upon Cell Lysis during Stationary Phase Is Essential for Aerobic Survival of a Pseudomonas aeruginosa oxyR Mutant at Low ...
  Daniel J. Hassett, Eyad Alsabbagh, Kislay Parvatiyar, Michael L. Howell, Robert W. Wilmott, Urs A. Ochsner> ;Journal of Bacteriology. 2000 Aug 15
• 121 citations
  Bacterioferritin A Modulates Catalase A (KatA) Activity and Resistance to Hydrogen Peroxide in Pseudomonas aeruginosa
  Ju-Fang Ma, Urs A. Ochsner, Martin G. Klotz, Vagira K. Nanayakkara, Michael L. Howell, Zaiga Johnson, James E. Posey, Michael L. Vasil, John J. Monaco, Daniel J. Hassett> ;Journal of Bacteriology. 1999 Jun 15
• 78 citations
  Regulation of the Macrophage Vacuolar ATPase and Phagosome-Lysosome Fusion by Histoplasma capsulatum
  Jane E. Strasser, Simon L. Newman, Georgianne M. Ciraolo, Randal E. Morris, Michael L. Howell, Gary E. Dean> ;Journal of Immunology. 1999 May 15
• 54 citations
  Cloning and Characterization of the Pseudomonas aeruginosa zwf Gene Encoding Glucose-6-Phosphate Dehydrogenase, an Enzyme Important in Resistance to Methyl Viologen (P...
  Ju-Fang Ma, Paul W. Hager, Michael L. Howell, Paul V. Phibbs, Daniel J. Hassett> ;Journal of Bacteriology. 1998 Apr 1
• XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos.
  Howell M, Hill CS> ;EMBO J.. 1997-12-15
• 46 citations
  Fumarase C activity is elevated in response to iron deprivation and in mucoid, alginate-producing Pseudomonas aeruginosa: cloning and characterization of fumC and puri...
  Daniel J. Hassett, Michael L. Howell, P A Sokol, M L Vasil, Gary E. Dean> ;Journal of Bacteriology. 1997 Mar 1
• 81 citations
  An operon containing fumC and sodA encoding fumarase C and manganese superoxide dismutase is controlled by the ferric uptake regulator in Pseudomonas aeruginosa: fur m...
  Daniel J. Hassett, Michael L. Howell, U A Ochsner, M L Vasil, Z Johnson, Gary E. Dean> ;Journal of Bacteriology. 1997 Mar 1
• 126 citations
  Ferric uptake regulator (Fur) mutants of Pseudomonas aeruginosa demonstrate defective siderophore-mediated iron uptake, altered aerobic growth, and decreased superoxid...
  Daniel J. Hassett, P A Sokol, Michael L. Howell, Ju-Fang Ma, H T Schweizer, U A Ochsner, M L Vasil> ;Journal of Bacteriology. 1996 Jul 1
• 130 citations
  Cloning and characterization of the katB gene of Pseudomonas aeruginosa encoding a hydrogen peroxide-inducible catalase: purification of KatB, cellular localization, a...
  S M Brown, Michael L. Howell, M L Vasil, A J Anderson, Daniel J. Hassett> ;Journal of Bacteriology. 1995 Nov 1
• Vaccinia virus ribonucleotide reductase. Correlation between deoxyribonucleotide supply and demand.
  Howell ML, Roseman NA, Slabaugh MB, Mathews CK> ;J. Biol. Chem.. 1993-04-05
• Cloning of the vaccinia virus ribonucleotide reductase small subunit gene. Characterization of the gene product expressed in Escherichia coli.
  Howell ML, Sanders-Loehr J, Loehr TM, Roseman NA, Mathews CK, Slabaugh MB> ;J. Biol. Chem.. 1992-01-25
• Mutagenesis of Cerebratulus lacteus neurotoxin B-IV identifies NH2-terminal sequences important for biological activity.
  Howell, M. L., Blumenthal, K. M.> ;J Biol Chem. 1991 Jul 15
• Cloning and expression of a synthetic gene for Cerebratulus lacteus neurotoxin B-IV.
  Howell, M. L., Blumenthal, K. M.> ;J Biol Chem. 1989 Sep 15
• Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts.
  Laitala-Leinonen, T., Howell, M. L., Dean, G. E., Väänänen, H. K.> ;Mol Biol Cell. 1996 Jan
• Effects of base substituents on the hydration of B- and Z-DNA: correlations to the B- to Z-DNA transition.
  Kagawa, T. F., Howell, M. L., Tseng, K., Ho, P. S.> ;Nucleic Acids Res. 1993 Dec 25
• Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription.
  Ross, S., Cheung, E., Petrakis, T. G., Howell, M., Kraus, W. L., Hill, C. S.> ;EMBO J. 2006 Oct 4
• Join now to see all

Abstracts/Posters

• A Biomarker Signature to Predict Complete Response to Itacitinib and Corticosteroids in Acute Graft Versus Host Disease
  Michael D. Howell, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019