MichaelGKellyMD

PubMed

• Surgical risk score predicts suboptimal debulking or a major perioperative complication in patients with advanced epithelial ovarian, fallopian tube, or primary perito...
  Stashwick, C., Post, M.D., Arruda, J.S., Spillman, M.A., Behbakht, K., Davidson, S.A., Kelly, M.G.> ;Int J Gynecol Cancer. 2011 Nov
• Phase II Evaluation of Phenoxodiol in Combination With Cisplatin or Paclitaxel in Women With Platinum/Taxane-Refractory/Resistant Epithelial Ovarian, Fallopian Tube, o...
  Kelly, M.G., Mor, G., Husband, A., O'Malley, D.M., Baker, L., Azodi, M., Schwartz, P.E., Rutherford, T.J.> ;Int J Gynecol Cancer. 2011 May
• Large cell neuroendocrine carcinoma of the cervix: prognostic factors and survival advantage with platinum chemotherapy.
  Embry, J.R., Kelly, M.G., Post, M.D., Spillman, M.A.> ;Gynecol Oncol. 2011 Mar
• Identification and characterization of novel TRPV4 modulators.
  Vincent, F., Acevedo, A., Nguyen, M.T., Dourado, M., DeFalco, J., Gustafson, A., Spiro, P., Emerling, D.E., Kelly, M.G., Duncton, M.J.> ;Biochem Biophys Res Commun. 2009-11-20
• Preparation of heteroaryloxetanes and heteroarylazetidines by use of a Minisci reaction.
  Duncton, M.J., Estiarte, M.A., Johnson, R.J., Cox, M., O'Mahony, D.R., Edwards, W.T., Kelly, M.G.> ;J Org Chem. 2009-08-21
• Preparation of aryloxetanes and arylazetidines by use of an alkyl-aryl suzuki coupling.
  Duncton, M.J., Estiarte, M.A., Tan, D., Kaub, C., O'Mahony, D.R., Johnson, R.J., Cox, M., Edwards, W.T., Wan, M., Kincaid, J., Kelly, M.G.> ;Org Lett. 2008 Aug 7
• Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)e...
  Hirst, W.D., Andree, T.H., Aschmies, S., Childers, W.E., Comery, T.A., Dawson, L.A., Day, M., Feingold, I.B., Grauer, S.M., Harrison, B.L., Hughes, Z.A., Kao, J., Kell...> ;J Pharmacol Exp Ther. 2008 Apr
• Neoadjuvant chemotherapy lessens surgical morbidity in advanced ovarian cancer and leads to improved survival in stage IV disease.
  Hou, J.Y., Kelly, M.G., Yu, H., McAlpine, J.N., Azodi, M., Rutherford, T.J., Schwartz, P.E.> ;Gynecol Oncol. 2007 Apr
• Atypical presentations of carboplatin hypersensitivity reactions: characterization and management in patients with gynecologic malignancies.
  McAlpine, J.N., Kelly, M.G., O'malley, D.M., Azodi, M., Coombe, K., Schwartz, P.E., Rutherford, T.J.> ;Gynecol Oncol. 2006 Oct
• 404 citations
  TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer.
  Michael G. Kelly, Ayesha B. Alvero, Rui Chen, Dan-Arin Silasi, Vikki M. Abrahams, Serena Chan, Irene Visintin, Thomas J. Rutherford, Gil Mor> ;Cancer Research. 2006 Apr 1
• Malignant transformation of myomas: myth or reality?
  Schwartz, P.E., Kelly, M.G.> ;Obstet Gynecol Clin North Am. 2006 Mar
• Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapy.
  > ;Gynecol Oncol. 2005 Sep
• Synthesis and biological evaluation of benzodioxanylpiperazine derivatives as potent serotonin 5-HT(1A) antagonists: the discovery of Lecozotan.
  Childers, W. E.,Abou-Gharbia, M. A.,Kelly, M. G.,Andree, T. H.,Harrison, B. L.,Ho, D. M.,Hornby, G.,Huryn, D. M.,Potestio, L.,Rosenzweig-Lipson, S. J.,Schmid, J.,Smith...> ;J Med Chem. 2005 May 19
• Discovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides.
  Doherty, E. M.,Fotsch, C.,Bo, Y.,Chakrabarti, P. P.,Chen, N.,Gavva, N.,Han, N.,Kelly, M. G.,Kincaid, J.,Klionsky, L.,Liu, Q.,Ognyanov, V. I.,Tamir, R.,Wang, X.,Zhu, J....> ;J Med Chem. 2005 Jan 13
• Structure-activity relationship of (1-aryl-2-piperazinylethyl)piperazines: antagonists for the AGRP/melanocortin receptor binding.
  Arasasingham, P.N., Fotsch, C., Ouyang, X., Norman, M.H., Kelly, M.G., Stark, K.L., Karbon, B., Hale, C., Baumgartner, J.W., Zambrano, M., Cheetham, J., Tamayo, N.A.> ;J Med Chem. 2003 Jan 2
• 20 citations
  Chronic ectopic pregnancy: Two cases of acute rupture despite negative βHCG
  Daniel F. Brennan, Sanjay Kwatra, Michael Kelly, M. A. Dunn> ;The Journal of Emergency Medicine. 2000 Oct 1
• Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-DPhe-Arg-Trp-Lys]-NH(2).
  Fotsch, C., Smith, D. M., Adams, J. A., Cheetham, J., Croghan, M., Doherty, E. M., Hale, C., Jarosinski, M. A., Kelly, M. G., Norman, M. H., Tamayo, N. A., Xi, N., Bau...> ;Bioorg Med Chem Lett. 2003 Jul 21
• Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells.
  Chen, R., Alvero, A. B., Silasi, D. A., Kelly, M. G., Fest, S., Visintin, I., Leiser, A., Schwartz, P. E., Rutherford, T., Mor, G.> ;Oncogene. 2008 Aug 7
• The incidence and risk factors associated with postoperative delirium in geriatric patients undergoing surgery for suspected gynecologic malignancies.
  McAlpine, J. N., Hodgson, E. J., Abramowitz, S., Richman, S. M., Su, Y., Kelly, M. G., Luther, M., Baker, L., Zelterman, D., Rutherford, T. J., Schwartz, P. E.> ;Gynecol Oncol. 2008 May
• Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides.
  Fotsch, C., Han, N., Arasasingham, P., Bo, Y., Carmouche, M., Chen, N., Davis, J., Goldberg, M. H., Hale, C., Hsieh, F. Y., Kelly, M. G., Liu, Q., Norman, M. H., Smith...> ;Bioorg Med Chem Lett. 2005 Mar 15
• Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
  Vincent, F., Nguyen, M. T., Emerling, D. E., Kelly, M. G., Duncton, M. A.> ;Bioorg Med Chem Lett. 2009 Dec 01
• Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor.
  Defalco, J., Steiger, D., Gustafson, A., Emerling, D. E., Kelly, M. G., Duncton, M. A.> ;Bioorg Med Chem Lett. 2010 Jan 01
• Patients with uterine papillary serous cancers may benefit from adjuvant platinum-based chemoradiation.
  Kelly, M. G., O'Malley, D., Hui, P., McAlpine, J., Dziura, J., Rutherford, T. J., Azodi, M., Chambers, S. K., Schwartz, P. E.> ;Gynecol Oncol. 2004 Dec
• 1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors.
  Sabb, A. L., Vogel, R. L., Kelly, M. G., Palmer, Y., Smith, D. L., Andree, T. H., Schechter, L. E.> ;Bioorg Med Chem Lett. 2001 Apr 23
• The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core.
  Harrington, P. E., St Jean, D. J., Clarine, J., Coulter, T. S., Croghan, M., Davenport, A., Davis, J., Ghiron, C., Hutchinson, J., Kelly, M. G., Lott, F., Lu, J. Y., M...> ;Bioorg Med Chem Lett. 2010 Sep 15
• Join now to see all