MichaelJKozalMD

Professor & Senior Associate Dean for Veteran Affairs, Stanford University School of Medicine; Chief of Staff, VA Palo Alto Healthcare System

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Office
3801 Miranda Ave
Palo Alto, CA 94304
Phone+1 650-374-9610
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Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Infectious Disease, 1991 - 1994
University of Nebraska Medical Center College of MedicineResidency, Internal Medicine, 1988 - 1991
University of Nebraska College of MedicineClass of 1988

Certifications & Licensure

CT State Medical License 2000 - 2025
TX State Medical License 1999 - 2025
CA State Medical License 1991 - 2025
NE State Medical License 1990 - 2024
IA State Medical License 1995 - 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Clinical Trials

Pilot Study of a Raltegravir Based NRTI Sparing Regimen Start of enrollment: 2009 May 01
Completed
Not Applicable
Collection of Samples From HIV-1 Infected Individuals for Evaluation of the Aptima HIV-1 Assay Start of enrollment: 2014 Jan 01
Completed
Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic Subjects Start of enrollment: 2014 Dec 01
Completed
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients Start of enrollment: 2015 Feb 23
Active, not recruiting
Phase 3
Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults Start of enrollment: 2015 May 12
Terminated
Phase 2
Ibalizumab Plus Optimized Background Regimen in Patient With Multi-Drug Resistant HIV Start of enrollment: 2015 Aug 01
Completed
Phase 3
Ibalizumab Plus Optimized Background Regimen in Treatment-Experienced Patients With Multi-Drug Resistant HIV-1 Start of enrollment: 2016 Mar 01
Completed
Phase 3
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Publications & Presentations

PubMed

6 citations
Week 96 Genotypic and Phenotypic Results of the Fostemsavir Phase 3 BRIGHTE Study in Heavily Treatment-Experienced Adults Living with Multidrug-Resistant HIV-1.
Margaret Gartland, Pedro Cahn, Edwin DeJesus, Ricardo Sobhie Diaz, Robert Grossberg, Michael Kozal, Princy Kumar, Jean-Michel Molina, Fernando Mendo Urbina, Marcia Wan...> ;Antimicrobial Agents and Chemotherapy. 2022 Jun 21
5 citations
Evaluation of HIV-1 reservoir size and broadly neutralizing antibodies (bNAb) susceptibility in acute ART treated individuals.
Brian Moldt, Huldrych F. Günthard, Kimberly A. Workowski, Susan J. Little, Joseph J. Eron, Edgar T. Overton, Clara Lehmann, Casper Rokx, Michael J. Kozal, Rajesh T. Ga...> ;AIDS. 2021 Sep 29
70 citations
Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection
Michael J. Kozal, Judith A. Aberg, Gilles Pialoux, Pedro Cahn, Melanie Thompson, Jean-Michel Molina, Beatriz Grinsztejn, Ricardo Sobhie Diaz, Antonella Castagna, Princ...> ;The New England Journal of Medicine. 2020 Mar 25
10 citations
Long-term efficacy and safety of fostemsavir among subgroups of heavily treatment-experienced adults with HIV-1.
Peter Ackerman, Melanie Thompson, Jean-Michel Molina, Judith A. Aberg, Isabel Cassetti, Michael J. Kozal, Antonella Castagna, Marcelo Martins, Moti Ramgopal, Eduardo S...> ;AIDS. 2021 Jun 1
12 citations
Fostemsavir for the treatment of HIV.
Nikhil Seval, Cynthia Frank, Michael J. Kozal> ;Expert Review of Anti-Infective Therapy. 2021 Jan 4
9 citations
Transmitted HIV-1 drug resistance in a large international cohort using next-generation sequencing: results from the Strategic Timing of Antiretroviral Treatment (STAR...
John D. Baxter, David Dunn, Anna Tostevin, Rasmus L. Marvig, Marc Bennedbæk, Alessandro Cozzi-Lepri, Shweta Sharma, Michael J. Kozal, Mark Gompels, Angie N Pinto, Jens...> ;HIV Medicine. 2021 May 1
47 citations
Safety and efficacy of the HIV-1 attachment inhibitor prodrug fostemsavir in heavily treatment-experienced individuals: week 96 results of the phase 3 BRIGHTE study
Max Lataillade, Jacob Lalezari, Michael J. Kozal, Judith A. Aberg, Gilles Pialoux, Pedro Cahn, Melanie Thompson, Jean-Michel Molina, Santiago Moreno, Beatriz Grinsztej...> ;The Lancet. HIV. 2020 Nov 1
8 citations
SARS-CoV-2 detection in setting of viral swabs scarcity: Are MRSA swabs and viral swabs equivalent?
Daniel G. Federman, Shaili Gupta, Gary Stack, Sheldon Campbell, David R. Peaper, Louise M. Dembry, Ann Fisher, Asim F. Tarabar, Michael J. Kozal, Christopher B. Ruser> ;Plos One. 2020 Aug 5
1 citations
Ombitasvir/paritaprevir/ritonavir and dasabuvir±ribavirin for chronic HCV infection in US veterans with psychiatric disorders.
Michael Fuchs, Alexander Monto, Norbert Bräu, Mariem Charafeddine, Warren N. Schmidt, Michael J. Kozal, Susanna Naggie, Ramsey Cheung, Gretja Schnell, Yao Yu, Kristine...> ;Journal of Medical Virology. 2020 Feb 17
9 citations
Characterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study.
Elie Helou, Sheela V Shenoi, Tassos C. Kyriakides, Marie-Louise Landry, Michael J. Kozal, Lydia Barakat> ;Journal of the International Association of Providers of AIDS Care. 2017 May 1
12 citations
HIV Drug Resistance Mutations (DRMs) Detected by Deep Sequencing in Virologic Failure Subjects on Therapy from Hunan Province, China
Xi Chen, Xiaobai Zou, Jianmei He, Jun Zheng, Jennifer Chiarella, Michael J. Kozal> ;Plos One. 2016 Feb 19
2137 citations
Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a c...
Daniel D Murray, Kazuo Suzuki, Matthew Law, Jonel Trebicka, Jacquie Neuhaus, Deborah Wentworth, Margaret Johnson, Michael J. Vjecha, Anthony D. Kelleher, Sean Emery, B...> ;Plos One. 2015 Oct 14
27 citations
Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers
Wendy E. Walker, Sebastian Kurscheid, Samit R Joshi, Charlie A Lopez, Gerald Goh, Murim Choi, Lydia Barakat, John Francis, Ann Fisher, Maichael J Kozal, Heidi J Zapata...> ;Journal of Virology. 2015 May 15
50 citations
Global HIV-1 transmitted drug resistance in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial
John D. Baxter, David Dunn, Ellen White, Shweta Sharma, Anna Maria Geretti, Michael J. Kozal, Margaret A. Johnson, S. Jacoby, Josep M. Llibre, Jens D Lundgren> ;HIV Medicine. 2015 Apr 1
11 citations
Transmission of HIV drug resistance: lessons from sensitive screening assays
Anna Maria Geretti, Roger Paredes, Michael J. Kozal> ;Current Opinion in Infectious Diseases. 2015 Feb 1
8 citations
Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection.
Arjet Gega, Michael J. Kozal, Jennifer Chiarella, Evelyn Lee, Julia Peterson, Frederick Hecht, Teri Liegler, Elizabeth P. St. John, Birgitte B. Simen, Richard W. Price...> ;Journal of Virus Eradication. 2015 Jan 1
15 citations
Low-Frequency NNRTI-Resistant HIV-1 Variants and Relationship to Mutational Load in Antiretroviral-Naïve Subjects
Shaili Gupta, Max Lataillade, Tassos C. Kyriakides, Jennifer Chiarella, Elizabeth P. St. John, Suzin Webb, Elizabeth A. Moreno, Birgitte B. Simen, Michael J. Kozal> ;Viruses. 2014 Sep 16
20 citations
Deep Sequencing of HIV: Clinical and Research Applications
Shiven B. Chabria, Shaili Gupta, Michael J. Kozal> ;Annual Review of Genomics and Human Genetics. 2014 Sep 3
14 citations
Prevalence of WHO transmitted drug resistance mutations by deep sequencing in antiretroviral-naïve subjects in Hunan Province, China.
Zou Xiaobai, Chen Xi, Hongping Tian, Ann B. Williams, Honghong Wang, Jianmei He, Jun Zhen, Jennifer Chiarella, Lisebeth A. Blake, Gregory S. Turenchalk, Michael J. Kozal> ;Plos One. 2014 Jun 4
7 citations
Association between risk behaviors and antiretroviral resistance in HIV-infected patients receiving opioid agonist treatment.
Jeanette M. Tetrault, Michael J. Kozal, Jennifer Chiarella, Lynn E. Sullivan, An T. Dinh, David A. Fiellin> ;Journal of Addiction Medicine. 2013 Mar 1
26 citations
A study of financial incentives to reduce plasma HIV RNA among patients in care.
Steven Farber, Janet P. Tate, Cyndi Frank, David Ardito, Michael J. Kozal, Amy C. Justice, R. Scott Braithwaite> ;AIDS and Behavior. 2013 Feb 13
40 citations
Impact of Minority Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Resistance Genotype After Virologic Failure
Jonathan Z. Li, Roger Paredes, Heather J. Ribaudo, Michael J. Kozal, Evguenia S. Svarovskaia, Jeffrey A. Johnson, Anna Maria Geretti, Karin J. Metzner, Martin R. Jakob...> ;The Journal of Infectious Diseases. 2013 Mar 15
28 citations
Development of Elvitegravir Resistance and Linkage of Integrase Inhibitor Mutations with Protease and Reverse Transcriptase Resistance Mutations
Mark A. Winters, Robert M. Lloyd, Robert W. Shafer, Michael J. Kozal, Michael D. Miller, Mark Holodniy> ;Plos One. 2012 Jul 18
73 citations
A nucleoside- and ritonavir-sparing regimen containing atazanavir plus raltegravir in antiretroviral treatment-naïve HIV-infected patients: SPARTAN study results.
Michael J. Kozal, Sergio Lupo, Edwin DeJesus, Jean-Michel Molina, Cheryl McDonald, François Raffi, Jorge Benetucci, Marco Mancini, Rong Yang, Victoria Wirtz, Lisa Perc...> ;HIV Clinical Trials. 2012 May 1
31 citations
Virologic Failures on Initial Boosted-PI Regimen Infrequently Possess Low-Level Variants with Major PI Resistance Mutations by Ultra-Deep Sequencing
Max Lataillade, Jennifer Chiarella, Rong Yang, Michelle DeGrosky, Jonathan Uy, Daniel Seekins, Birgitte B. Simen, Elizabeth P. St. John, Elizabeth A. Moreno, Michael J...> ;Plos One. 2012 Feb 15
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Journal Articles

Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection
Michael Kozal, Edwin Dejesus, Cyril Llamoso, The New England Journal of Medicine

Other

Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection
Michael Kozal, MD, The New England Journal of Medicine
https://www.doximity.com/articles/53c3f551-51dc-4278-9eda-95049ceeac02
UpToDate, Wolters Kluwer Health - 2012-12-06
Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection
Michael Kozal, MD, New England Journal of Medicine
https://www.doximity.com/articles/53c3f551-51dc-4278-9eda-95049ceeac02
UpToDate, Wolters Kluwer Health - 2013-02-19