MichaelTunyinLamMDPhD(He/Him)

PubMed

• 66 citations
  Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients: a case series and review of the literature.
  Patel, A., Jorge A. Masso-Silva, A. Moshensky, Michael T. Lam, Mazen Odish, Arjun Patel, Le Xu, Emily Hansen, Samantha Trescott, Celina Nguyen, Roy Kim, Katherine Pero...> ;Clinical Infectious Diseases. 2021 May 14
• Lungs can tell time-a highlight from 2016 ATS session on clock genes, inflammation, immunology, and sleep.
  Lam MT, Grandner MA, Malhotra A> ;Journal of thoracic disease.
• 3 citations
  Enhancer RNAs.
  Wenbo Li, Michael T Y Lam, Dimple Notani> ;Cell Cycle. 2014 Jan 1
• 94 citations
  Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis
  Yung Hae Kim, Huiqing Hu, Michael T. Lam, Shun-Yin Fong, Rong Wang> ;Development. 2008 Nov 15
• 8 citations
  OSA as a probable risk factor for severe COVID-19.
  Michael T. Lam, Atul Malhotra> ;Journal of Clinical Sleep Medicine. 2020 Sep 15
• Use of Electronic Cigarettes with Conventional Tobacco Is Associated with Decreased Sleep Quality in Women.
  Boddu SA, Bojanowski CM, Lam MT, Advani IN, Scholten EL, Sun X, Montgrain P, Malhotra A, Jain S, Alexander LEC> ;American journal of respiratory and critical care medicine.
• Timing Matters: Circadian Rhythm in Sepsis, Obstructive Lung Disease, Obstructive Sleep Apnea, and Cancer.
  Truong KK, Lam MT, Grandner MA, Sassoon CS, Malhotra A> ;Annals of the American Thoracic Society.
• PPARs and lipid ligands in inflammation and metabolism.
  Harmon GS, Lam MT, Glass CK> ;Chemical reviews.
• 2 citations
  Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients.
  Patel, A., Michael Tun Yin Lam, Sascha H Duttke, Mazen F Odish, Hiep D Le, Emily A Hansen, Celina T Nguyen, Samantha Trescott, Roy Kim, Shaunak Deota, Max W Chang, Arj...> ;Cell Reports. Medicine. 2023 Feb 21
• 1 citations
  Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis.
  Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donog...> ;Frontiers in Molecular Biosciences. 2022 Jan 1
• 8 citations
  Absolute quantification of plasma mitochondrial DNA by droplet digital PCR marks COVID-19 severity over time during intensive care unit admissions.
  Mark L Hepokoski, Mazen Odish, Michael T Lam, Nicole G Coufal, Mark L Rolfsen, Gerald S Shadel, Alexandra G Moyzis, Alva G Sainz, Puja G Takiar, Sagar Patel, Austin J ...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Jul 1
• ATS Core Curriculum 2020. Adult Sleep Medicine.
  Jamil SM, Owens RL, Lipford MC, Shafazand S, Marron RM, Vega Sanchez ME, Lam MT, Sunwoo BY, Schmickl C, Orr JE, Sharma S, Sankari A, Javaheri S, Bertisch S, Dupuy-McCa...> ;ATS scholar. 2020-12-30
• 223 citations
  Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment
  Gabriele Sulli, Michael Tun Yin Lam, Satchidananda Panda> ;Trends in Cancer. 2019 Aug 1
• 58 citations
  Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells.
  Nicholas T Hogan, Michael B. Whalen, Lindsey K. Stolze, Michael T. Lam, James R. Springstead, Christopher K. Glass, Casey E. Romanoski> ;Elife. 2017 Jun 6
• SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism.
  Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A,...> ;Cell metabolism. 2016-12-29
• 56 citations
  Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages
  Dawn Z Eichenfield, Ty D. Troutman, Michael T. Lam, Han Cho, David Gosselin, Nathanael J. Spann, Hanna P. Lesch, Jenhan Tao, Jun Muto, Richard L. Gallo, Ronald M. Evan...> ;Elife. 2016 Jul 27
• Enhancer RNAs and regulated transcriptional programs.
  Lam MT, Li W, Rosenfeld MG, Glass CK> ;Trends in biochemical sciences. 2014-03-24
• 50 citations
  25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages
  , , , , , , , , , , , , , , , , , , , , , , , , > ;The Journal of Biological Chemistry. 2013 Dec 13
• Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.
  Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK> ;Nature. 2013-06-02
• Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β.
  Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM> ;Nature. 2012-03-29
• 371 citations
  Non-coding RNAs as regulators of gene expression and epigenetics.
  Michael T. Lam, Christopher K. Glass, Minna U. Kaikkonen> ;Cardiovascular Research. 2011 Jun 1
• 106 citations
  Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice
  Michael T. Lam, Xiaoqing Wu, Tyson N. Kim, Shant M. Vartanian, Andrew W. Bollen, Timothy R. Carlson, Rong Wang> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 5
• 152 citations
  Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice
  Timothy R. Carlson, Yibing Yan, Michael T. Lam, Gale L. Tang, Levi J. Beverly, Louis M. Messina, Anthony J. Capobianco, Zena Werb, Rong Wang> ;Proceedings of the National Academy of Sciences of the United States of America. 2005 Jul 12
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Journal Articles

• Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription  
  Michael T. Y. Lam, Han Cho, Hanna P. Lesch, David Gosselin, Sven Heinz, Yumiko Tanaka-Oishi, Christopher Benner, Minna U. Kaikkonen, Aneeza S. Kim, Mika Kosaka, Cindy ..., Nature, 6/2/2013