MichaelR.LebensMD

PubMed

• 29 citations
  Construction and preclinical evaluation of mmCT, a novel mutant cholera toxin adjuvant that can be efficiently produced in genetically manipulated Vibrio cholerae
  Michael Lebens, Manuela Terrinoni, Stefan L. Karlsson, Maximilian Larena, Tobias Gustafsson-Hedberg, Susanne Källgård, Erik Nygren, Jan Holmgren> ;Vaccine. 2016 Apr 19
• 55 citations
  Cholera Toxin, and the Related Nontoxic Adjuvants mmCT and dmLT, Promote Human Th17 Responses via Cyclic AMP–Protein Kinase A and Inflammasome-Dependent IL-1 Signaling
  Maximilian Larena, Jan Holmgren, Michael Lebens, Manuela Terrinoni, Anna Lundgren> ;Journal of Immunology. 2015 Apr 15
• 26 citations
  Development of stable Vibrio cholerae O1 Hikojima type vaccine strains co-expressing the Inaba and Ogawa lipopolysaccharide antigens.
  Stefan L. Karlsson, Elisabeth Ax, Erik Nygren, Susanne Källgård, Margareta Blomquist, Annelie Ekman, John Benktander, Jan Holmgren, Michael Lebens> ;Plos One. 2014 Nov 14
• 6 citations
  The repertoire of glycosphingolipids recognized by Vibrio cholerae.
  John Benktander, Jonas Ångström, Hasse Karlsson, Omid Teymournejad, Sara K. Lindén, Michael Lebens, Susann Teneberg> ;Plos One. 2013 Jan 21
• 24 citations
  Construction of a non-toxigenic Escherichia coli oral vaccine strain expressing large amounts of CS6 and inducing strong intestinal and serum anti-CS6 antibody respons...
  Joshua Tobias, Ann-Mari Svennerholm, Nils Carlin, Michael Lebens, Jan Holmgren> ;Vaccine. 2011 Nov 8
• 19 citations
  Construction of novel vaccine strains of Vibrio cholerae co-expressing the Inaba and Ogawa serotype antigens.
  Michael Lebens, Stefan L. Karlsson, Susanne Källgård, Margareta Blomquist, Annelie Ekman, Erik Nygren, Jan Holmgren> ;Vaccine. 2011 Oct 6
• 448 citations
  Evidence for several waves of global transmission in the seventh cholera pandemic
  Ankur Mutreja, Dong Wook Kim, Nicholas R. Thomson, Thomas R. Connor, Jehee Lee, Samuel Kariuki, Nicholas J. Croucher, Seon Young Choi, Simon R. Harris, Michael Lebens,...> ;Nature. 2011 Sep 22
• 19 citations
  Crystal structures exploring the origins of the broader specificity of escherichia coli heat-labile enterotoxin compared to cholera toxin.
  Åsa Holmner, Alasdair Mackenzie, Mats Ökvist, Lena Jansson, Michael Lebens, Susann Teneberg, Ute Krengel> ;Journal of Molecular Biology. 2010 Dec 8
• 19 citations
  Over-expression of major colonization factors of enterotoxigenic Escherichia coli, alone or together, on non-toxigenic E. coli bacteria
  Joshua Tobias, Jan Holmgren, Maria Hellman, Erik Nygren, Michael Lebens, Ann-Mari Svennerholm> ;Vaccine. 2010 Oct 8
• 12 citations
  Carbohydrate binding specificities and crystal structure of the cholera toxin-like B-subunit from Citrobacter freundii☆
  Lena Jansson, Jonas Ångström, Michael Lebens, Anne Imberty, Annabelle Varrot, Susann Teneberg> ;Biochimie. 2010 May 1
• 155 citations
  Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis
  Roland Klingenberg, Michael Lebens, Andreas Hermansson, Gunilla Nordin Fredrikson, Daniela Strodthoff, Mats Rudling, Daniel F. J. Ketelhuth, Norbert Gerdes, Jan Holmgr...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 May 1
• 14 citations
  Construction and expression of immunogenic hybrid enterotoxigenic Escherichia coli CFA/I and CS2 colonization fimbriae for use in vaccines.
  Joshua Tobias, Ann-Mari Svennerholm, Jan Holmgren, Michael Lebens> ;Applied Microbiology and Biotechnology. 2010 Apr 20
• 7 citations
  No direct binding of the heat-labile enterotoxin of Escherichia coli to E. coli lipopolysaccharides
  Lena Jansson, Jonas Ångström, Michael Lebens, Susann Teneberg> ;Glycoconjugate Journal. 2010 Jan 1
• 24 citations
  CD4+ T-cell responses to an oral inactivated cholera vaccine in young children in a cholera endemic country and the enhancing effect of zinc supplementation.
  Tanvir Ahmed, Mohammad Arifuzzaman, Michael Lebens, Firdausi Qadri, Anna Lundgren> ;Vaccine. 2009 Dec 11
• 39 citations
  Sulfatide Recognition by Colonization Factor Antigen CS6 from Enterotoxigenic Escherichia coli
  Lena Jansson, Joshua Tobias, Catharina Jarefjäll, Michael Lebens, Ann-Mari Svennerholm, Susann Teneberg> ;Plos One. 2009 Feb 16
• 24 citations
  Role of different genes in the CS6 operon for surface expression of Enterotoxigenic Escherichia coli colonization factor CS6.
  Joshua Tobias, Michael Lebens, Susanne Källgård, Matilda Nicklasson, Ann-Mari Svennerholm> ;Vaccine. 2008 Oct 3
• 18 citations
  Mutations in the periplasmic chaperone leading to loss of surface expression of the colonization factor CS6 in enterotoxigenic Escherichia coli (ETEC) clinical isolates.
  Matilda Nicklasson, Åsa Sjöling, Michael Lebens, Joshua Tobias, Anders Janzon, Lars Brive, Ann-Mari Svennerholm> ;Microbial Pathogenesis. 2008 Mar 1
• 28 citations
  Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I fimbriae.
  Joshua Tobias, Michael Lebens, Ingrid Bölin, Gudrun Wiklund, Ann-Mari Svennerholm> ;Vaccine. 2008 Feb 6
• 35 citations
  Novel Binding Site Identified in a Hybrid between Cholera Toxin and Heat-Labile Enterotoxin: 1.9 Å Crystal Structure Reveals the Details
  Åsa Holmner, Michael Lebens, Susann Teneberg, Jonas Ångström, Mats Ökvist, Ute Krengel> ;Structure. 2007 Feb 1
• 20 citations
  Oral tolerance induction by mucosal administration of cholera toxin B‐coupled antigen involves T‐cell proliferation in vivo and is not affected by depletion of CD25+ T...
  Annie George Chandy, Susanne Hultkrantz, Sukanya Raghavan, Cecil Czerkinsky, Michael Lebens, Esbjörn Telemo, Jan Holmgren> ;Immunology. 2006 Jul 1
• 60 citations
  The Major Subunit, CfaB, of Colonization Factor Antigen I from Enterotoxigenic Escherichia coli Is a Glycosphingolipid Binding Protein
  Lena Jansson, Joshua Tobias, Michael Lebens, Ann-Mari Svennerholm, Susann Teneberg> ;Infection and Immunity. 2006 Jun 1
• 168 citations
  Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.
  Jan Holmgren, Jenni Adamsson, Fabienne Anjuère, John D. Clemens, Cecil Czerkinsky, Kristina Eriksson, Carl-Fredrik Flach, Annie George-Chandy, Ali M. Harandi, Michael ...> ;Immunology Letters. 2005 Mar 15
• 75 citations
  In vivo adjuvant-induced mobilization and maturation of gut dendritic cells after oral administration of cholera toxin.
  Fabienne Anjuère, Carmelo Luci, Michael Lebens, Déborah Rousseau, Catherine Hervouet, Geneviève Milon, Jan Holmgren, Carlos Ardavín, Cecil Czerkinsky> ;Journal of Immunology. 2004 Oct 15
• 36 citations
  Current status and future prospects for a vaccine against schistosomiasis.
  Michael Lebens, Jia-Bin Sun, Cecil Czerkinsky, Jan Holmgren> ;Expert Review of Vaccines. 2004 Jun 1
• 29 citations
  A mucosally administered recombinant fusion protein vaccine against schistosomiasis protecting against immunopathology and infection.
  Michael Lebens, Jia-Bin Sun, Hamid Sadeghi, Malin Bäckström, Ida Olsson, Nathalie Mielcarek, Bin-Ling Li, André Capron, Cecil Czerkinsky, Jan Holmgren> ;Vaccine. 2003 Jan 17
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