MichaelLeeMD

PubMed

• 27 citations
  Astrocyte-neuronal network interplay is disrupted in Alzheimer's disease mice.
  Justin Lines, Andrés M. Baraibar, Cenxiao Fang, Eduardo D. Martín, Juan Aguilar, Michael K. Lee, Alfonso Araque, Paulo Kofuji> ;Glia. 2021 Nov 2
• 3 citations
  UNC-45A Is Highly Expressed in the Proliferative Cells of the Mouse Genital Tract and in the Microtubule-Rich Areas of the Mouse Nervous System
  Asumi Hoshino, Joyce Meints, Mihir Shetty, Timothy K. Starr, Michael K. Lee, Martina Bazzaro, Valentino Clemente> ;Cells. 2021 Jun 26
• 25 citations
  Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson’s Disease
  Philipp Portz, Michael K. Lee> ;Cells. 2021 Apr 13
• 31 citations
  Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
  Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace A. Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno,...> ;Communications Biology. 2021 Jan 8
• 15 citations
  Ablating Tau Reduces Hyperexcitability and Moderates Electroencephalographic Slowing in Transgenic Mice Expressing A53T Human α-Synuclein.
  Samuel T. Peters, Allyssa Fahrenkopf, Jessica M. Choquette, Scott C. Vermilyea, Michael K. Lee, Keith A. Vossel> ;Frontiers in Neurology. 2020 Jun 19
• 31 citations
  α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment
  Md. Razaul Karim, Elly E. Liao, Jaekwang Kim, Joyce Meints, Hector Martell Martinez, Olga Pletnikova, Juan C. Troncoso, Michael K. Lee> ;Molecular Neurodegeneration. 2020 Apr 16
• 23 citations
  Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson’s disease
  Milos Stanojlovic, Jean Pierre Pallais, Michael K. Lee, Catherine M. Kotz> ;Molecular Brain. 2019 Oct 30
• 47 citations
  Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
  Ana Covelo, Héctor A. Martell-Martínez, Carmen Nanclares, Mathew A. Sherman, Joyce Meints, Peter J. Teravskis, Christopher Gallardo, Alena Savonenko, Michael A. Benney...> ;Acta Neuropathologica. 2019 Jun 6
• 48 citations
  A53T Mutant Alpha-Synuclein Induces Tau-Dependent Postsynaptic Impairment Independently of Neurodegenerative Changes.
  Peter J. Teravskis, Ana Covelo, Eric C. Miller, Héctor A. Martell-Martínez, Michael A. Benneyworth, Christopher Gallardo, Breeta R. Oxnard, Alfonso Araque, Michael K. ...> ;The Journal of Neuroscience. 2018 Nov 7
• 16 citations
  UNC-45A is a Novel Microtubule-associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells
  Ashley Mooneyham, Yoshie Iizuka, Qing Yang, Courtney Coombes, Mark McClellan, Vijayalakshmi Shridhar, Edith Emmings, Mihir Shetty, Liqiang Chen, Teng Ai, Joyce Meints,...> ;Molecular Cancer Research. 2019 Feb 1
• 28 citations
  Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons
  Shahzad S. Khan, Michael LaCroix, Gabriel Boyle, Mathew A. Sherman, Jennifer L. Brown, Fatou Amar, Jacqeline Aldaco, Michael K. Lee, George S. Bloom, Sylvain Lesné> ;Acta Neuropathologica. 2018 Jul 11
• 20 citations
  Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons
  Emanuela Colla, Giulia Panattoni, Alessio Ricci, Caterina Rizzi, Lucia Rota, Nicola Maria Carucci, Verdiana Valvano, Francesco Gobbo, Simona Capsoni, Michael K. Lee, A...> ;Neurobiology of Disease. 2018 Mar 1
• 143 citations
  α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton.
  Dalila G. Ordonez, Michael K. Lee, Mel B. Feany> ;Neuron. 2018 Jan 3
• 38 citations
  Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease.
  Santiago V. Salazar, Christopher Gallardo, Adam C. Kaufman, Charlotte Herber, Laura T. Haas, Sophie A. Robinson, Jean Manson, Michael K. Lee, Stephen M. Strittmatter> ;The Journal of Neuroscience. 2017 Sep 20
• 40 citations
  Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
  Megan Larson, Susan Greimel, Fatou Amar, Michael LaCroix, Gabriel Boyle, Mathew A. Sherman, Hallie Schley, Camille Miel, Julie A. Schneider, Rakez Kayed, Fabio Benfena...> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jun 6
• 91 citations
  Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification.
  Byung Chul Jung, Yoon Ju Lim, Eun Jin Bae, Jun Sung Lee, Choi Min Sun, Michael K. Lee, He Jin Lee, Yoon Suk Kim, Seung-Jae Lee> ;Experimental & Molecular Medicine. 2017 Apr 7
• 9 citations
  UNC-45A is Required for Neurite Extension via Controlling NMII activation.
  Yoshie Iizuka, Ashley Mooneyham, Andrew Sieben, Kevin Chen, Makayla Maile, Raffaele Hellweg, Florian Schütz, Kebebush Teckle, Timothy K. Starr, Venugopal Thayanithy, R...> ;Molecular Biology of the Cell. 2017 Mar 29
• 29 citations
  Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.
  L. Zhao, Majda Hadziahmetovic, Chenguang Wang, Xueying Xu, Ying Song, Hyder A. Jinnah, Jolanta Wodzinska, Jared Iacovelli, Natalie Wolkow, Predrag Krajacic, Alyssa Cwa...> ;Journal of Neurochemistry. 2015 Dec 1
• 21 citations
  UNC-45A Is a Nonmuscle Myosin IIA Chaperone Required for NK Cell Cytotoxicity via Control of Lytic Granule Secretion
  Yoshie Iizuka, Frank Cichocki, Andrew Sieben, Fabio Sforza, Razaul Karim, Kathleen Coughlin, Rachel Isaksson Vogel, Riccardo Gavioli, Valarie McCullar, Todd Lenvik, Mi...> ;Journal of Immunology. 2015 Oct 5
• 129 citations
  Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer
  Derek Marshall, Susan K. Lyman, Scott Alan Mccauley, Maria Kovalenko, Rhyannon Spangler, Chian Liu, Michael K. Lee, Christopher O’Sullivan, Vivian Barry-Hamilton, Habe...> ;Plos One. 2015 May 11
• 3 citations
  Method for measuring the activity of deubiquitinating enzymes in cell lines and tissue samples
  Percy Griffin, Ashley Sexton, Lauren Macneill, Yoshie Iizuka, Michael K. Lee, Martina Bazzaro> ;Journal of Visualized Experiments. 2015 May 10
• 50 citations
  Small-Molecule RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer In Vitro and In Vivo via Exacerbating Unfolded Protein Responses
  Kathleen Coughlin, Ravi K. Anchoori, Yoshie Iizuka, Joyce Meints, Lauren Macneill, Rachel Isaksson Vogel, Robert Z. Orlowski, Michael K. Lee, Richard B.S. Roden, Marti...> ;Clinical Cancer Research. 2014 Jun 15
• 249 citations
  Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future
  Yonas E. Geda, Lon S. Schneider, Laura N. Gitlin, David S. Miller, Gwenn S. Smith, Joanne Bell, Jovier D. Evans, Michael K. Lee, Anton P. Porsteinsson, Krista L. Lanct...> ;Alzheimer's & Dementia. 2013 Sep 1
• Comparison of Adolescents' Reports of Sexual Behavior on a Survey and Sexual Health History Calendar.
  Fisher, C. M.,Lee, M. G.> ;J Sex Res. 2013 Jul 11
• 21 citations
  Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6...
  Gary Probst, Danielle L. Aubele, Simeon Bowers, Darren B. Dressen, Albert W. Garofalo, Roy K. Hom, Andrei W. Konradi, Jennifer Marugg, Matthew N. Mattson, Martin L. Ne...> ;Journal of Medicinal Chemistry. 2013 Jun 20
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Journal Articles

• A53T Mutant Alpha-Synuclein Induces Tau Dependent Postsynaptic Impairment Independent of Neurodegenerative Changes  
  Peter J Teravskis, Michael K Lee, Breeta R Oxnard, The Journal of Neuroscience
• Bidirectional Modulation of Alzheimer Phenotype by Alpha-Synuclein in Mice and Primary Neurons  
  Michael Lee, MD, Acta Neuropathologica