MichaelMaitlandMDPhD

Oncology • Fairfax, VA

Hematologic Oncology

Professor of Medicine, University of Virginia

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Office
8081 Innovation Park Dr
Fairfax, VA 22031
Phone+1 571-472-1180

Fax+1 571-472-1197
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Education & Training

University of ChicagoFellowship, Hematology and Medical Oncology, 2003 - 2005
Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 2002 - 2003
New York Presbyterian Hospital (Cornell Campus)Residency, Internal Medicine, 2000 - 2002
Albert Einstein College of MedicineClass of 2000

Certifications & Licensure

VA State Medical License 2016 - 2024
IL State Medical License 2003 - 2017
NY State Medical License 2002 - 2004

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Sorafenib in Treating Patients With Advanced Solid Tumors Start of enrollment: 2007 Jan 01
Terminated
Phase 1
INNO-206 in Patients With Small Cell Lung Cancer (SCLC) Start of enrollment: 2008 May 01
Withdrawn
Phase 2
Dose Escalation of Bevacizumab With Ambulatory Blood Pressure Monitoring in Patients With Advanced Non-squamous NSCLC Start of enrollment: 2010 Mar 01
Completed
Not Applicable
Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme Start of enrollment: 2009 Dec 01
Terminated
Phase 1
High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid Tumors Start of enrollment: 2011 Feb 09
Active, not recruiting
Phase 1
Phase 1 Study of OTS167 in Patients With Solid Tumors Start of enrollment: 2013 Aug 23
Completed
Phase 1
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Publications & Presentations

PubMed

Model-based approach to identify predictors of paclitaxel-induced myelosuppression in "real-world" administration.
Ahmed M Salem, Erik Dvergsten, Sanja Karovic, Michael L Maitland, Mathangi Gopalakrishnan> ;CPT. 2023 Jul 1
5 citations
Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer WithAmplification, Overexpression, or Mutation: Results From the TAPUR Study.
Eugene R Ahn, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Hussein M Ali-Ahmad, John Chan, Michael L Maitland, Sapna R Patel, Zachary Reese, Ani S Balmanoukia...> ;JCO Precision Oncology. 2023 Apr 1
4 citations
Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150.
René Bruno, Mathilde Marchand, Kenta Yoshida, Phyllis Chan, Haocheng Li, Wei Zou, Francois Mercier, Pascal Chanu, Benjamin Wu, Anthony Lee, Chunze Li, Jin Y Jin, Micha...> ;Clinical Cancer Research. 2023 Mar 14
Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome.
Bin Ni, Shanshan Chen, Kathleen A Ryan, Michael L Maitland, Jared S Farrar, Martin Witzenrath, Birgitt Gubier, Cindy Serdjebi, Karine Bertotti, Rui Wang, Fadi N Sallou...> ;Molecular Metabolism. 2022 Nov 1
35 citations
Early Readout on Overall Survival of Patients With Melanoma Treated With Immunotherapy Using a Novel Imaging Analysis.
Laurent Dercle, Binsheng Zhao, Mithat Gönen, Chaya S Moskowitz, Ahmed Firas, Volkan Beylergil, Dana E Connors, Hao Yang, Lin Lu, Tito Fojo, Richard Carvajal, Sanja Kar...> ;JAMA Oncology. 2022 Mar 1
4 citations
An imaging signature to predict outcome in metastatic colorectal cancer using routine computed tomography scans.
Laurent Dercle, Binsheng Zhao, Mithat Gönen, Chaya S Moskowitz, Dana E Connors, Hao Yang, Lin Lu, Diane Reidy-Lagunes, Tito Fojo, Sanja Karovic, Michael L Maitland, Ge...> ;European Journal of Cancer. 2022 Jan 1
476 citations
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis.
Julian D Gillmore, Ed Gane, Jorg Taubel, Justin Kao, Marianna Fontana, Michael L Maitland, Jessica Seitzer, Daniel O'Connell, Kathryn R Walsh, Kristy Wood, Jonathan Ph...> ;The New England Journal of Medicine. 2021 Aug 5
31 citations
First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody-Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors.
Michael L. Maitland, Jasgit C. Sachdev, Manish R. Sharma, Victor Moreno, Valentina Boni, Shivaani Kummar, Erica Stringer-Reasor, Nehal Lakhani, Allison R Moreau, Dawei...> ;Clinical Cancer Research. 2021 Aug 15
11 citations
Comparing RECIST 1.1 and iRECIST in advanced melanoma patients treated with pembrolizumab in a phase II clinical trial
Firas S. Ahmed, Laurent Dercle, Gregory V. Goldmacher, Hao Yang, Dana E. Connors, Ying Tang, Sanja Karovic, Binsheng Zhao, Richard D. Carvajal, Caroline Robert, Michae...> ;European Radiology. 2021 Apr 1
1 citations
Identifying Novel Drug Targets by iDTPnd: A Case Study of Kinase Inhibitors.
Hammad Naveed, Corinna Reglin, Thomas Schubert, Xin Gao, Stefan T. Arold, Michael L. Maitland> ;Genomics, Proteomics & Bioinformatics. 2021 Mar 29
Evaluation of publicly available in vitro drug sensitivity models for ovarian and uterine cancer.
Danielle C. Kimble, Erik Dvergsten, Vasiliki Thomeas-McEwing, Sanja Karovic, Thomas P. Conrads, Michael L. Maitland> ;Gynecologic Oncology. 2021 Jan 1
10 citations
Enhanced Detection of Treatment Effects on Metastatic Colorectal Cancer with Volumetric CT Measurements for Tumor Burden Growth Rate Evaluation.
Michael L. Maitland, Julia Wilkerson, Sanja Karovic, Binsheng Zhao, Jessica Flynn, Mengxi Zhou, Patrick Hilden, Firas S. Ahmed, Laurent Dercle, Chaya S. Moskowitz, Yin...> ;Clinical Cancer Research. 2020 Sep 28
Risk of COVID-19 in Patients With Cancer.
Michael L. Maitland, David Heyer, Mardi Gomberg-Maitland> ;JAMA Oncology. 2020 Sep 1
6 citations
Get Real: Integration of Real-World Data to Improve Patient Care
Ron J. Keizer, Erik Dvergsten, Andrej Kolacevski, Aaron Black, Sanja Karovic, Srijib Goswami, Michael L. Maitland> ;Clinical Pharmacology and Therapeutics. 2020 Apr 1
3 citations
Cancer Clinical Investigators Should Converge with Pharmacometricians.
Michael L. Maitland, Roisin E. O'Cearbhaill, Jogarao V. S. Gobburu> ;Clinical Cancer Research. 2019 Jun 27
11 citations
A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors
Amikar Sehdev, Theodore Karrison, Yuanyuan Zha, Linda Janisch, Michelle Turcich, Ezra E.W. Cohen, Michael Maitland, Blase N. Polite, Thomas F. Gajewski, Ravi Salgia, N...> ;Cancer Chemotherapy and Pharmacology. 2018 Jun 9
10 citations
Comparison of tumor size assessments in tumor growth inhibition-overall survival models with second-line colorectal cancer data from the VELOUR study
Laurent Claret, Christina Pentafragka, Sanja Karovic, Binsheng Zhao, Lawrence H. Schwartz, Michael L. Maitland, Rene Bruno> ;Cancer Chemotherapy and Pharmacology. 2018 Apr 26
14 citations
Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial.
Michael L. Maitland, Sarina Anne Piha-Paul, Gerald Steven Falchook, Razelle Kurzrock, Ly M. Nguyen, Linda Janisch, Sanja Karovic, Mark D. McKee, Elizabeth Hoening, She...> ;British Journal of Cancer. 2018 Mar 19
12 citations
Vol-PACT: A Foundation for the NIH Public-Private Partnership That Supports Sharing of Clinical Trial Data for the Development of Improved Imaging Biomarkers in Oncology.
Laurent Dercle, Dana E. Connors, Ying Tang, Stacey J Adam, Mithat Gonen, Patrick Hilden, Sanja Karovic, Michael L. Maitland, Chaya S. Moskowitz, Gary J. Kelloff, Binsh...> ;JCO Clinical Cancer Informatics. 2018 Mar 2
36 citations
PharmGKB summary: sorafenib pathways.
Li Gong, Marilyn M. Giacomini, Craig P. Giacomini, Michael L. Maitland, Russ B. Altman, Teri E. Klein> ;Pharmacogenetics and Genomics. 2017 Jun 1
18 citations
Pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies and hepatic impairment.
Ghassan K. Abou-Alfa, Lionel D. Lewis, Patricia LoRusso, Michael L. Maitland, Priya Chandra, Sravanthi Cheeti, Dawn Colburn, Sarah Williams, B. Simmons, Richard A. Graham> ;Cancer Chemotherapy and Pharmacology. 2017 May 18
2 citations
A Pharmacokinetic and Safety Study of Trebananib, an Fc-Fusion Peptibody, in Patients With Advanced Solid Tumors and Varying Degrees of Renal Dysfunction.
Benjamin Wu, Lionel D. Lewis, R. D. Harvey, Erik Rasmussen, Erick Gamelin, Yu-Nien Sun, Gregory Friberg, Jay L. Koyner, Afshin Dowlati, Michael L. Maitland> ;Clinical Pharmacology and Therapeutics. 2017 Aug 1
25 citations
First-in-human study of the antibody DR5 agonist DS-8273a in patients with advanced solid tumors
Andres Forero, Johanna C. Bendell, Prasanna Kumar, Linda Janisch, Michael Rosen, Qiang Wang, Catherine Copigneaux, Madhuri Desai, Giorgio Senaldi, Michael L. Maitland> ;Investigational New Drugs. 2017 Jan 3
7 citations
Patient-Level Adverse Event Patterns in a Single-Institution Study of the Multi-Kinase Inhibitor Sorafenib
S Karovic, Eileen Shiuan, SQ Zhang, Hongyuan Cao, ML Maitland> ;Clinical and Translational Science. 2016 Oct 1
Improving clinical trial design through quantitative pharmacology.
Michael L. Maitland> ;Clinical Advances in Hematology & Oncology. 2016 Aug 1
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Press Mentions

Public-Private Research Effort to Develop More Accurate Ways of Measuring Cancer ProgressionMarch 27th, 2017
Shop TalkSeptember 25th, 2016
Shop TalkSeptember 20th, 2016
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