Michael Mannstadt MD
Osteoporosis & Bone Metabolism Medicine, Parathyroid
Chief, Endocrine Unit, Massachusetts General Hospital Associate Professor of Medicine, Harvard Medical School
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55 Fruit StWang ACC 730a Endocrine AssociatesBoston, MA 02114
Phone+1 617-726-8720
Fax+1 617-724-2718
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Summary
- Dr. Michael Mannstadt is an endocrinologist based in Boston, MA, specializing in bone and parathyroid disorders. He completed his fellowship in endocrinology, diabetes, and metabolism at Massachusetts General Hospital, where he serves as an attending physician since 2007 and Chief of the Endocrine Unit. His areas of expertise include disorders of calcium and bone metabolism such as fibrous dysplasia, osteoporosis, and hypo- and hyperparathyroidism. Dr. Mannstadt's research contributions include >120 publications, such as studies on patients with hypoparathyroidism, genetic disorders and FD. He has been involved in multiple clinical trials focusing on novel treatments for hypoparathyroidism and served as Co-Chair of the International Workshop in Hypoparathyroidism and Hyperparathyroidism
Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2004 - 2007- Mass General Brigham/Massachusetts General HospitalChief Residency, Internal Medicine, 2005 - 2006
- Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 2001 - 2004
Friedrich-Schiller-Universität JenaClass of 1991
Certifications & Licensure
MA State Medical License 2003 - 2026
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 1 Certification Longitudinal Medical Record, Partners Healthcare System, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
Clinical Trials
- A Open-label Study Investigating the Safety and Tolerability of NPSP558, a Recombinant Human Parathyroid Hormone (rhPTH [1-84]), for the Treatment of Adults With Hypoparathyroidism - A Clinical Extension Study (RACE) Start of enrollment: 2011 Apr 06
- A Registry for Participants With Chronic Hypoparathyroidism Start of enrollment: 2013 Jul 30
- A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidism Start of enrollment: 2020 Jul 23
Publications & Presentations
PubMed
- Multiple Endocrine Neoplasia Type 5 due to Germline MAX Mutations: A Systematic Review of Tumor Spectrum and Clinical Features.Nipith Charoenngam, Natapong Thaneerat, Pornlada Likasitwatanakul, Chalermkiat Kansuttiviwat, Michael Mannstadt
Endocrine Practice. 2025-12-30 - Comment on "Pre-Operative Vitamin D Supplementation to Reduce Hypocalcemia Following Total Thyroidectomy: Systematic Review and Meta-Analysis of Randomized Clinical Tr...Luca Canali, Gian Marco Pace, Marika D Russell, Francesca Gaino, Luca Malvezzi
Head & Neck. 2025-12-01 - Plasma proteomic markers of pain and emotional dysfunction in fibrous dysplasia/McCune-Albright syndrome.Camryn Berry, Evan E Hsu, Courtney LeSon, Kailey E Brodeur, Edin Randall
Bone. 2025-12-01
Journal Articles
- A New Multi-System Disorder Caused by the Gαs Mutation p.F376VMichael Mannstadt, MD, The Journal of Clinical Endocrinology and Metabolism
Lectures
- Challenges in Treating Hypoparathyroid Patients (Repeat)ENDO 2019 - New Orleans, LA - 3/24/2019
- Challenges in Treating Hypoparathyroid PatientsENDO 2019 - New Orleans, LA - 3/24/2019
- Genetics of Calcium RegulationENDO 2018: 100th Endocrine Society Annual Meeting - Chicago, Illinios - 03/20/2018
Press Mentions
BridgeBio Hits Phase 3 Win for Calcium Deficiency Candidate, Plots FDA Review Next YearOctober 29th, 2025
Recall of Takeda's Natpara Leaves Patients in Health LimboSeptember 16th, 2019
Understanding Healthy Bone Growth in Childhood to Improve Long-Term Quality of LifeApril 29th, 2014
Grant Support
- R01NIH NIDDKPresent
Professional Memberships
- Member
- American Society of Bone and Mineral ResearchMember
External Links
- Research Homepagehttp://www.massgeneral.org/research/researchlab.aspx?id=1256
- Lab Homepagehttps://mannstadt.mgh.harvard.edu
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