MichaelBMartinMD

PubMed

• Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia.
  Janes, M. R.,Vu, C.,Mallya, S.,Shieh, M. P.,Limon, J. J.,Li, L. S.,Jessen, K. A.,Martin, M. B.,Ren, P.,Lilly, M. B.,Sender, L. S.,Liu, Y.,Rommel, C.,Fruman, D. A.> ;Leukemia. 2013 Mar
• 54 citations
  Selective Inhibition of Phosphoinositide 3- Kinase p110α Preserves Lymphocyte Function *
  Lomon So, Sung Su Yea, Jean S. Oak, Mengrou Lu, Arun Manmadhan, Qiao Han Ke, Matthew R. Janes, Linda V. Kessler, Jeff M. Kucharski, Lian-Sheng Li, Michael B. Martin, P...> ;The Journal of Biological Chemistry. 2013 Feb 22
• Defining the role of TORC1 and TORC2 in multiple myeloma.
  Maiso, P., Liu, Y., Morgan, B., Azab, A., Ren, P., Martin, M.B., Zhang, Y., Liu, Y., Sacco, A., Ngo, H., Azab, F., Quang, P., Rodig, S.J., Lin, C.P., Roccaro, A., Romm...> ;Blood. 2011 Dec 22
• Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
  Janes, M.R., Limon, J.J., So, L., Chen, J., Lim, R.J., Chavez, M.A., Vu, C., Lilly, M.B., Mallya, S., Ong, S.T., Konopleva, M., Martin, M.B., Ren, P., Liu, Y., Rommel,...> ;Nat Med. 2010 Feb
• Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits.
  Scheppke, L., Aguilar, E., Gariano, R.F., Jacobson, R., Hood, J., Doukas, J., Cao, J., Noronha, G., Yee, S., Weis, S., Martin, M.B., Soll, R., Cheresh, D.A., Friedland...> ;J Clin Invest. 2008 Jun
• TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations.
  Pardanani, A., Hood, J., Lasho, T., Levine, R. L., Martin, M. B., Noronha, G., Finke, C., Mak, C. C., Mesa, R., Zhu, H., Soll, R., Gilliland, D. G., Tefferi, A.> ;Leukemia. 2007 Aug
• An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.
  Szabo, C.M., Martin, M.B., Oldfield, E.> ;J Med Chem. 2002 Jul 4
• Activity of bisphosphonates against Trypanosoma brucei rhodesiense.
  Martin, M.B., Sanders, J.M., Kendrick, H., de Luca-Fradley, K., Lewis, J.C., Grimley, J.S., Van Brussel, E.M., Olsen, J.R., Meints, G.A., Burzynska, A., Kafarski, P., ...> ;J Med Chem. 2002 Jul 4
• Radical cure of experimental cutaneous leishmaniasis by the bisphosphonate pamidronate.
  Rodriguez, N., Bailey, B.N., Martin, M.B., Oldfield, E., Urbina, J.A., Docampo, R.> ;J Infect Dis. 2002 Jul 1
• 65 citations
  Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents
  Christina M. Szabo, Yoshihiro Matsumura, Sayaka Fukura, Michael B. Martin, John M. Sanders, Suraj Sengupta, John A. Cieslak, Timothy C. Loftus, Christopher R. Lea, Hyu...> ;Journal of Medicinal Chemistry. 2002 May 23
• In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii.
  Yardley, V., Khan, A.A., Martin, M.B., Slifer, T.R., Araujo, F.G., Moreno, S.J., Docampo, R., Croft, S.L., Oldfield, E.> ;Antimicrob Agents Chemother. 2002 Mar
• Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase.
  Montalvetti, A., Bailey, B. N., Martin, M. B., Severin, G. W., Oldfield, E., Docampo, R.> ;J Biol Chem. 2001 Sep 7
• (31)P NMR of apicomplexans and the effects of risedronate on Cryptosporidium parvum growth.
  Moreno, B., Bailey, B. N., Luo, S., Martin, M. B., Kuhlenschmidt, M., Moreno, S. N., Docampo, R., Oldfield, E.> ;Biochem Biophys Res Commun. 2001 Jun 15
• Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to ch...
  Martin, M. B., Grimley, J. S., Lewis, J. C., Heath, H. T., Bailey, B. N., Kendrick, H., Yardley, V., Caldera, A., Lira, R., Urbina, J. A., Moreno, S. N., Docampo, R., ...> ;J Med Chem. 2001 Mar 15
• Effects of arsenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells.
  Stoica, A., Pentecost, E., Martin, M. B.> ;Endocrinology. 2000 Oct
• Effects of selenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells.
  Stoica, A., Pentecost, E., Martin, M. B.> ;J Cell Biochem. 2000 Aug 2
• Regulation of estrogen receptor-alpha gene expression by epidermal growth factor.
  Stoica, A., Saceda, M., Doraiswamy, V. L., Coleman, C., Martin, M. B.> ;J Endocrinol. 2000 May
• Activation of estrogen receptor-alpha by the heavy metal cadmium.
  Stoica, A., Katzenellenbogen, B. S., Martin, M. B.> ;Mol Endocrinol. 2000 Apr
• Role of insulin-like growth factor-I in regulating estrogen receptor-alpha gene expression.
  Stoica, A., Saceda, M., Fakhro, A., Joyner, M., Martin, M. B.> ;J Cell Biochem. 2000 Jan
• Regulation of estrogen receptor-alpha gene expression by 1, 25-dihydroxyvitamin D in MCF-7 cells.
  Stoica, A., Saceda, M., Fakhro, A., Solomon, H. B., Fenster, B. D., Martin, M. B.> ;J Cell Biochem. 1999 Dec 15
• Nitrogen-containing bisphosphonates as carbocation transition state analogs for isoprenoid biosynthesis.
  Martin, M. B., Arnold, W., Heath, H. T., Urbina, J. A., Oldfield, E.> ;Biochem Biophys Res Commun. 1999 Oct 5
• Estradiol regulates estrogen receptor mRNA stability.
  Saceda, M., Lindsey, R. K., Solomon, H., Angeloni, S. V., Martin, M. B.> ;J Steroid Biochem Mol Biol. 1998 Aug
• Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.
  Stewart, A. O., Bhatia, P. A., Martin, J. G., Summers, J. B., Rodriques, K. E., Martin, M. B., Holms, J. H., Moore, J. L., Craig, R. A., Kolasa, T., Ratajczyk, J. D., ...> ;J Med Chem. 1997 Jun 20
• The role of transforming growth factor-beta in the regulation of estrogen receptor expression in the MCF-7 breast cancer cell line.
  Stoica, A., Saceda, M., Fakhro, A., Solomon, H. B., Fenster, B. D., Martin, M. B.> ;Endocrinology. 1997 Apr
• Erythrocytapheresis therapy to reduce iron overload in chronically transfused patients with sickle cell disease.
  Kim, H. C., Dugan, N. P., Silber, J. H., Martin, M. B., Schwartz, E., Ohene-Frempong, K., Cohen, A. R.> ;Blood. 1994 Feb 15
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