MichaelSMegaMD

Neurology • Portland, OR

Dementia & Geriatrics

Neurologist physician at Providence Health & Services - Oregon

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Office
Center for Cognitive Health
10200 SW Eastridge St Suite 105
Portland, OR 97225
Phone+1 503-207-2066

Fax+1 503-548-4981
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Education & Training

MedStar Health/Georgetown University HospitalInternship, Internal Medicine, 1988 - 1989
George Washington University School of Medicine and Health SciencesClass of 1988

Certifications & Licensure

CA State Medical License 1993 - Present
OR State Medical License 1993 - 2025
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012

Publications & Presentations

PubMed

10 citations
Stress-Induced Neurodegeneration: The Potential for Coping as Neuroprotective Therapy.
Shelby A Kline, Michael S Mega> ;American Journal of Alzheimer's Disease and Other Dementias. 2020 Sep 24
39 citations
Automated brain tissue assessment in the elderly and demented population: construction and validation of a sub-volume probabilistic brain atlas.
Michael S. Mega, Ivo D. Dinov, John C. Mazziotta, Mario Manese, Paul M. Thompson, Chris Lindshield, Jacob Moussai, Nah Tran, Kirsten Olsen, Chris I. Zoumalan, Roger P....> ;Neuroimage. 2005 Jul 15
69 citations
Metabolic patterns associated with the clinical response to galantamine therapy: a fludeoxyglucose f 18 positron emission tomographic study.
Michael S. Mega, Ivo D. Dinov, Verna Porter, George Chow, Erin Reback, Paras Davoodi, Susan M. O'Connor, Michele Carter, Herminia Amezcua, Jeffrey L. Cummings> ;Archives of Neurology. 2005 May 1
12 citations
A wavelet-based statistical analysis of FMRI data: I. motivation and data distribution modeling.
Ivo D. Dinov, John W. Boscardin, Michael S. Mega, Elizabeth L. Sowell, Arthur W. Toga> ;Neuroinformatics. 2005 Jan 1
80 citations
Agitation in Alzheimer’s Disease Is a Manifestation of Frontal Lobe Dysfunction
Vorapun Senanarong, Jeffrey L. Cummings, Lynn A. Fairbanks, Michael S. Mega, Donna M. Masterman, Susan M. O'Connor, Tony L. Strickland> ;Dementia and Geriatric Cognitive Disorders. 2004 Jan 1
Differential diagnosis of dementia: clinical examination and laboratory assessment.
Michael S Mega> ;Clinical Cornerstone. 2002 Jan 1
13 citations
A Transcultural Study of Agitation in Dementia
Jong Ling Fuh, Michael S. Mega, Giuliano Binetti, Shuu Jiun Wang, Eugenio Magni, Jeffrey L. Cummings> ;Journal of Geriatric Psychiatry and Neurology. 2002 Sep 1
35 citations
Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space.
Michael S. Mega, Gary W. Small, Mina L. Xu, Jenaro Felix, Mario Manese, Nha P Tran, Jason I Dailey, Linda M. Ercoli, Susan Y. Bookheimer, Arthur W. Toga> ;Psychosomatic Medicine. 2002 May 1
125 citations
Frontal White Matter Biochemical Abnormalities in Late-Life Major Depression Detected With Proton Magnetic Resonance Spectroscopy
Anand Kumar, Albert Thomas, Helen Lavretsky, Kenneth Yue, Amir Huda, John Curran, Talaignair N. Venkatraman, Laverne Estanol, Jim Mintz, Michael S. Mega, Arthur W. Toga> ;The American Journal of Psychiatry. 2002 Apr 1
18 citations
Quantitative comparison and analysis of brain image registration using frequency-adaptive wavelet shrinkage
Ivo D. Dinov, Michael S. Mega, Paul M. Thompson, Roger P. Woods, D.L. Sumners, Elizabeth L. Sowell, Arthur W. Toga> ;IEEE Transactions on Information Technology in Biomedicine. 2002 Mar 1
32 citations
Probabilistic approaches for atlasing normal and disease-specific brain variability.
Arthur W. Toga, Paul M. Thompson, Michael S. Mega, Katherine L. Narr, Rebecca E. Blanton> ;Anatomy and Embryology. 2001 Oct 1
300 citations
Neuropsychiatric aspects of Huntington's disease
Jane S. Paulsen, Rebecca E. Ready, J. M. Hamilton, Michael S. Mega, Jeffrey L. Cummings> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2001 Sep 1
46 citations
Detecting Disease-Specific Patterns of Brain Structure Using Cortical Pattern Matching and a Population-Based Probabilistic Brain Atlas
Paul M. Thompson, Michael S. Mega, Christine N. Vidal, Judith L. Rapoport, Arthur W. Toga> ;Information Processing in Medical Imaging. 2001 Jun 18
102 citations
Behavioral disorders and caregivers' reaction in Taiwanese patients with Alzheimer's disease.
Jong Ling Fuh, Ching-Kuan Liu, Michael S. Mega, Shuu Jiun Wang, Jeffrey L. Cummings> ;International Psychogeriatrics. 2001 Mar 1
219 citations
Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease.
Sibel Tekin, Michael S. Mega, Donna M. Masterman, Tiffany W. Chow, Justine Garakian, Harry V. Vinters, Jeffrey L. Cummings> ;Annals of Neurology. 2001 Mar 1
316 citations
Cortical Change in Alzheimer's Disease Detected with a Disease-specific Population-based Brain Atlas
Paul M. Thompson, Michael S. Mega, Roger P. Woods, Chris I. Zoumalan, Chris Lindshield, Rebecca E. Blanton, Jacob Moussai, Colin J. Holmes, Jeffrey L. Cummings, Arthur...> ;Cerebral Cortex. 2001 Jan 1
42 citations
Cognitive and metabolic responses to metrifonate therapy in Alzheimer disease.
Michael S. Mega, Jeffrey L. Cummings, Susan M. O'Connor, Ivo D. Dinov, Erin Reback, Jenaro Felix, Donna Masterman, Michael E. Phelps, Gary W. Small, Arthur W. Toga> ;Neuropsychiatry, Neuropsychology, and Behavioral Neurology. 2001 Jan 1
137 citations
Cerebral correlates of psychotic symptoms in Alzheimer's disease
Michael S. Mega, Linda Lee, Ivo D. Dinov, Fred S. Mishkin, Arthur W. Toga, Jeffrey L. Cummings> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2000 Aug 1
22 citations
The cholinergic deficit in Alzheimer's disease: impact on cognition, behaviour and function
Michael S. Mega> ;The International Journal of Neuropsychopharmacology. 2000 Jul 1
15 citations
Disease-specific probabilistic brain atlases
Paul M. Thompson, Michael S. Mega, Arthur W. Toga> ;Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. 2000 Jun 11
80 citations
Left Frontotemporal Hypoperfusion Is Associated With Aggression in Patients With Dementia
Nobutsugu Hirono, Michael S. Mega, Ivo D. Dinov, Fred S. Mishkin, Jeffrey L. Cummings> ;Archives of Neurology. 2000 Jun 1
563 citations
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
Gary W. Small, Linda M. Ercoli, Daniel H.S. Silverman, Sung-Cheng Huang, Scott Komo, Susan Y. Bookheimer, Helen Lavretsky, Karen J. Miller, Prabha Siddarth, Natalie L....> ;Proceedings of the National Academy of Sciences of the United States of America. 2000 May 23
71 citations
Orbital and dorsolateral frontal perfusion defect associated with behavioral response to cholinesterase inhibitor therapy in Alzheimer's disease.
Michael S. Mega, Ivo D. Dinov, Linda Lee, Susan M. O'Connor, Donna M. Masterman, Barry Wilen, Fred S. Mishkin, Arthur W. Toga, Jeffrey L. Cummings> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2000 May 1
229 citations
Mathematical/computational challenges in creating deformable and probabilistic atlases of the human brain
Paul M. Thompson, Roger P. Woods, Michael S. Mega, Arthur W. Toga> ;Human Brain Mapping. 2000 Feb 1
32 citations
Analyzing functional brain images in a probabilistic atlas: a validation of subvolume thresholding.
Ivo D. Dinov, Michael S. Mega, Paul M. Thompson, Linda Lee, Roger P. Woods, Colin J. Holmes, De Witt L. Sumners, Arthur W. Toga> ;Journal of Computer Assisted Tomography. 2000 Jan 1
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