Michael C Milone MD
Blood Banking & Transfusion Medicine, Anatomic Pathology, Clinical Pathology
Assistant Professor, Pathology & Laboratory Medicine, Perelman School of Medicine
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3400 Spruce StPhiladelphia, PA 19104
Phone+1 215-662-6503
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Education & Training
University of Pennsylvania Health SystemFellowship, Blood Banking/Transfusion Medicine, 2002 - 2003- University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 2000 - 2002
- University of Pennsylvania Health SystemInternship, Internal Medicine, 1999 - 2000
Rutgers New Jersey Medical SchoolClass of 1999
Certifications & Licensure
PA State Medical License 2002 - 2026
American Board of Pathology Clinical Pathology
Publications & Presentations
PubMed
- Concept CARs are picking up speed.Jorge Mansilla-Soto, Michael C Milone
Molecular Therapy. 2025-06-04 - Clinical advances in gene, cell, and RNA therapies.Michael C Milone, Jorge Mansilla-Soto, Norbert Pardi, Lindsey A George, Barry J Byrne
Molecular Therapy. 2025-06-04 - 1 citationsQuadruple adenine base-edited allogeneic CAR T cells outperform CRISPR/Cas9 nuclease-engineered T cells.Nils W Engel, Israel Steinfeld, Daniel Ryan, Kusala Anupindi, Samuel Kim
Proceedings of the National Academy of Sciences of the United States of America. 2025-05-20
Journal Articles
- Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-Exposure SARS-CoV-2 Prophylaxis Among Health Care WorkersMatthew C Hyman, Ian Frank, Scott E Hensley, Saar Gill, Dan T Vogl, Ivan Maillard, Daria V Babushok, Alexander C Huang, Sunita D Nasta, Jennifer C Walsh, Michael C Mil..., JAMA Internal Medicine
- CAR T Cell Immunotherapy for Human CancerCarl H June, Michael C Milone, Science Magazine
- High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma ModelStephan A Grupp, Zissimos Mourelatos, Michael C Milone, David M Barrett, Sarah A Richman, Clinical Cancer Research
Lectures
- Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Re...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- PD-1 Inhibitor Combinations As Salvage Therapy for Relapsed/Refractory Multiple Myeloma (MM) Patients Progressing after Bcma-Directed CAR T Cells2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Clinical Predictors of T Cell Fitness for CAR T Cell Manufacturing and Efficacy in Multiple Myeloma2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Press Mentions
Penn Medicine Breakthrough Immunotherapy Technique Could Reduce Cost of Cancer TreatmentApril 12th, 2022- Research Roundup: Scientists May Have Solved CAR-T Turnaround ChallengeApril 1st, 2022
FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University of Pennsylvania and Children’s Hospital of PhiladelphiaAugust 30th, 2017- Join now to see all
Grant Support
- Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantationUNIVERSITY OF PENNSYLVANIA2021–2028
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