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Michael Moskowitz, MD, Neurology, Boston, MA

MichaelArthurMoskowitzMD

Neurology Boston, MA

Headache

Professor, Neurology, Massachusetts General Hospital, Harvard Medical School

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Summary

  • I am Board Certified in Internal Medicine and Neurology. My major interest is research in stroke and migraine. My research training took place at M.I.T. where my research in migraine led to the development of the CGRP receptor antagonists. My lab discovered and introduced the concept of the trigeminovascular system as a final common path for headache pain and proposed neuropeptides as targets for therapy. My lab also showed a mechanism of action for the ergot alkaloids that largely replaced the vasoconstrictor theories regarding their action. For this I won the Brain Prize from the Lundbeck Foundation and presented by the Crown Prince of Denmark. This is the largest prize given in neuroscience and 1.5 million Danish Kroner was shared with 3 other investigators from Sweden, Denmark and Australia. My research in stroke laid the basis for using nitric oxide targeting drugs for therapy. That therapeutic application is just beginning.

Education & Training

  • Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical School
    Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1971 - 1974
  • Yale-New Haven Medical Center
    Yale-New Haven Medical CenterResidency, Internal Medicine, 1968 - 1971
  • Tufts University School of Medicine
    Tufts University School of MedicineClass of 1968

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1971 - 2023
  • PA State Medical License
    PA State Medical License 1971 - 1976
  • American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

  • Doctor Honoris Causa Clermont Auvergne University, 2022
  • Brain Prize 2021 Lundbeck Foundation, 2021
  • Doctor Honoris Causa University of Athens, Greece, 2019
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Publications & Presentations

PubMed

Journal Articles

  • Direct Vascular Channels Connect Skull Bone Marrow and the Brain Surface Enabling Myeloid Cell Migration  
    Michael A Moskowitz, Ralph Weissleder, Nature

Press Mentions

  • Skull Channels Shown to Protect Brain from Infection
    Skull Channels Shown to Protect Brain from InfectionMay 2nd, 2022
  • Hallmarks of Alzheimer’s Found Well Before Diagnosis
    Hallmarks of Alzheimer’s Found Well Before DiagnosisMay 2nd, 2022

Grant Support

  • Administrative CoreNational Institute Of Neurological Disorders And Stroke2007–2011
  • Migraine Pathophysiology And Treatment MechanismsNational Institute Of Neurological Disorders And Stroke2001–2011
  • Migraine Drug ProphylaxisNational Institute Of Neurological Disorders And Stroke2008–2010
  • Cortical Spreading Depression, Proteases And IschemiaNational Institute Of Neurological Disorders And Stroke2008
  • HMG1 Signaling In Inflammation Following Brain IschemiaNational Institute Of Neurological Disorders And Stroke2007–2008
  • Cortical Spreading Depression, Proteases And IschemiaNational Institute Of Neurological Disorders And Stroke2004–2008
  • Interdepartmental Stroke ProgramNational Institute Of Neurological Disorders And Stroke1989–2008
  • Migraine Drug ProphylaxisNational Institute Of Neurological Disorders And Stroke2006–2007
  • Cortical Spreading Depression, Proteases And IschemiaNational Institute Of Neurological Disorders And Stroke2004–2007
  • Interdepartmental Stroke ProgramNational Institute Of Neurological Disorders And Stroke1991–2007
  • Caspase Mechanisms After Brain InjuryNational Institute Of Neurological Disorders And Stroke2002–2006
  • Core--AdministrativeNational Institute Of Neurological Disorders And Stroke2004
  • Interdepartmental Stroke Program ProjectNational Institute Of Neurological Disorders And Stroke1999–2003
  • Roll Of Dural Inos Expression In MigraineNational Institute Of Neurological Disorders And Stroke2001–2002
  • Prophylactic Hmg-Coa Reductase Inhibitors In StrokeNational Institute Of Neurological Disorders And Stroke1999–2002
  • Caspase Inhibitors Protect Ischemic BrainNational Institute Of Neurological Disorders And Stroke1998–2001
  • Trigeminal Nerve--Control Of The Brain VasculatureNational Institute Of Neurological Disorders And Stroke1996–2000
  • Migraine--Pathophysiology And Treatment MechanismsNational Institute Of Neurological Disorders And Stroke1996–2000
  • Core--ScientificNational Institute Of Neurological Disorders And Stroke1996–1999
  • Nitric Oxide As Mediator In Cerebrovascular DilationNational Institute Of Neurological Disorders And Stroke1996–1998
  • Interdepartment Stroke ProgramNational Institute Of Neurological Disorders And Stroke1994–1998
  • Trigeminal Vasomotor Effects On The Cerebral CirculationNational Institute Of Neurological Disorders And Stroke1988–1995
  • Trigeminal Nerve--Control Of The Brain VasculatureNational Institute Of Neurological Disorders And Stroke1985–1995
  • 19th Conference On Cerebrovascular DiseaseNational Institute Of Neurological Disorders And Stroke1994
  • Trigeminal Nerve: Control Of The Brain VasculatureNational Institute Of Neurological Disorders And Stroke1993
  • Opioid Peptide Gene Expression In Nucleus CaudalisNational Institute Of Neurological Disorders And Stroke1989–1992
  • Trigeminal Vasomotor Effects On The Cerebral CirculationNational Institute Of Neurological Disorders And Stroke1991
  • Trigeminal Nerve: Control Of The Brain VasculatureNational Institute Of Neurological Disorders And Stroke1991
  • CNS Vascular Cells In Cultures: Arachidonate MetabolismNational Institute Of Neurological Disorders And Stroke1985–1986
  • Trigeminovascular Control Of Cerebral Blood VesselsNational Institute Of Neurological Disorders And Stroke1985