MichaelRNicholsMD

PubMed

• 26 citations
  Aβ42 Protofibrils Interact with and Are Trafficked through Microglial-Derived Microvesicles
  Lisa K. Gouwens, Mudar S Ismail, Victoria A. Rogers, Nathan T Zeller, Evan C. Garrad, Fatima S. Amtashar, Nyasha J. Makoni, David Osborn, Michael R. Nichols> ;ACS Chemical Neuroscience. 2018 Mar 15
• 18 citations
  The conformational epitope for a new Aβ42 protofibril-selective antibody partially overlaps with the peptide N-terminal region.
  Benjamin A. Colvin, Victoria A. Rogers, Joshua A. Kulas, Elizabeth A. Ridgway, Fatima S. Amtashar, Colin K. Combs, Michael R. Nichols> ;Journal of Neurochemistry. 2017 Nov 22
• 45 citations
  APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease
  Gunjan D. Manocha, Angela M. Floden, Keiko Rausch, Joshua A. Kulas, Brett A. McGregor, Lalida Rojanathammanee, Kelley R. Puig, Kendra L. Puig, Sanjib Karki, Michael R....> ;The Journal of Neuroscience. 2016 Aug 10
• 9 citations
  CD47 does not mediate amyloid-β(1–42) protofibril-stimulated microglial cytokine release
  Sanjib Karki, Michael R. Nichols> ;Biochemical and Biophysical Research Communications. 2014 Nov 7
• 27 citations
  Amyloid-β(1-42) protofibrils formed in modified artificial cerebrospinal fluid bind and activate microglia
  Geeta S. Paranjape, Shana E. Terrill, Lisa K. Gouwens, Benjamin M. Ruck, Michael R. Nichols> ;Journal of Neuroimmune Pharmacology. 2013 Mar 1
• 4 citations
  Substituted tryptophans at amyloid-β(1-40) residues 19 and 20 experience different environments after fibril formation.
  Ryan T. McDonough, Geeta S. Paranjape, Fabio Gallazzi, Michael R. Nichols> ;Archives of Biochemistry and Biophysics. 2011 Oct 1
• 80 citations
  Amyloid-β Protofibrils Differ from Amyloid-β Aggregates Induced in Dilute Hexafluoroisopropanol in Stability and Morphology *
  Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Stephanie Cratic-McDaniel, Jan H. Hoh, Terrone L. Rosenberry> ;The Journal of Biological Chemistry. 2005 Jan 28
• 24 citations
  Rapid Assembly of Amyloid-β Peptide at a Liquid/Liquid Interface Produces Unstable β-Sheet Fibers†
  Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Jan H. Hoh, Terrone L. Rosenberry> ;Biochemistry. 2005 Jan 11
• 26 citations
  Nordihydroguaiaretic acid does not disaggregate beta-amyloid(1-40) protofibrils but does inhibit growth arising from direct protofibril association.
  Moss, M. A., Varvel, N. H., Nichols, M. R., Reed, D. K., Rosenberry, T. L.> ;Molecular pharmacology. 2004 Aug 24
• 129 citations
  Growth of β-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force micros...
  Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Wen Lang Lin, Rajendrani Mukhopadhyay, Jan H. Hoh, Terrone L. Rosenberry> ;Biochemistry. 2002 May 14
• 33 citations
  Tyrosine kinase-independent inhibition of cyclic-AMP phosphodiesterase by genistein and tyrphostin 51.
  Michael R. Nichols, Bruce H. Morimoto> ;Archives of Biochemistry and Biophysics. 1999 Jun 15
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