MichaelOffinMD

PubMed

• Response letter to "Stereotactic body radiation therapy for pleural mesothelioma: Which goal, which patients".
  Jacob Y Shin, Michael Offin, Charles B Simone 2nd, Annemarie F Shepherd, Abraham J Wu, Narek Shaverdian, Daphna Y Gelblum, Daniel R Gomez, Jennifer L Sauter, Michelle ...> ;Radiotherapy and Oncology. 2024 Apr 1
• A plain language summary of the PHAROS study: the combination of encorafenib and binimetinib for people with BRAF V600E-mutant metastatic non-small cell lung cancer.
  Riely, G., Smit, E., Ahn, M., Felip, E., Ramalingam, S., Tsao, A., Johnson, M., Gelsomino, F., Esper, R., Nadal, E., Offin, M., Provencio, M., Clarke, J., Hussein, M.,...> ;Future Oncology. 2024 Feb 15
• Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma.
  Christopher A Febres-Aldana, Jason C Chang, Achim A Jungbluth, Prasad S Adusumilli, Francis M Bodd, Denise Frosina, Jerica A Geronimo, Enmily Hernandez, Helen Irawan, ...> ;Modern Pathology. 2024 Mar 1
• 1 citations
  Clinical outcomes of stereotactic body radiation therapy for malignant pleural mesothelioma.
  Zhang, Z., Shin, J., Offin, M., Shepherd, A., Wu, A., Shaverdian, N., Gelblum, D., Gomez, D., Sauter, J., Ginsberg, M., Adusumilli, P., Rusch, V., Zauderer, M., Rimner...> ;Radiotherapy and Oncology. 2024 Feb 1
• Exploring published and novel pre-treatment CT and PET radiomics to stratify risk of progression among early-stage non-small cell lung cancer patients treated with ste...
  Thor, M., Fitzgerald, K., Apte, A., Oh, J., Iyer, A., Odiase, O., Nadeem, S., Yorke, E., Chaft, J., Wu, A., Offin, M., Simone Ii, C., Preeshagul, I., Gelblum, D., Gome...> ;Radiotherapy and Oncology. 2024 Jan 1
• 1 citations
  Diffuse Pleural Mesothelioma: Advances in Molecular Pathogenesis, Diagnosis, and Treatment.
  Christopher A Febres-Aldana, Rachel Fanaroff, Michael Offin, Marjorie G Zauderer, Jennifer L Sauter, Soo-Ryum Yang, Marc Ladanyi> ;Annual Review of Pathology. 2024 Jan 24
• 5 citations
  MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer.
  Lars D Engstrom, Ruth Aranda, Laura Waters, Krystal Moya, Vickie Bowcut, Laura Vegar, David Trinh, Allan Hebbert, Christopher R Smith, Svitlana Kulyk, J David Lawson, ...> ;Cancer Discovery. 2023 Nov 1
• 6 citations
  Phase II, Open-Label Study of Encorafenib Plus Binimetinib in Patients With-Mutant Metastatic Non-Small-Cell Lung Cancer.
  Gregory J Riely, Egbert F Smit, Myung-Ju Ahn, Enriqueta Felip, Suresh S Ramalingam, Anne Tsao, Melissa Johnson, Francesco Gelsomino, Raymond Esper, Ernest Nadal, Micha...> ;Journal of Clinical Oncology. 2023 Jul 20
• 1 citations
  Reliability of assessing morphologic features with prognostic significance in cytology specimens of epithelioid diffuse pleural mesothelioma and implications for cytop...
  Yan Li, Abeer M Salama, Marina K Baine, Francis M Bodd, Michael D Offin, Natasha Rekhtman, Marjorie G Zauderer, William D Travis, Prasad S Adusumilli, Jennifer L Sauter> ;Cancer Cytopathology. 2023 Aug 1
• 1 citations
  Clinical Outcomes Associated With Pembrolizumab Monotherapy Among Adults With Diffuse Malignant Peritoneal Mesothelioma.
  Melina E Marmarelis, Xiao Wang, Leonid Roshkovan, Connor B Grady, John T Miura, Michelle S Ginsberg, Christine A Ciunci, Jacklynn Egger, Suzanne Walker, Andrea Cercek,...> ;JAMA Network Open. 2023 Mar 1
• 2 citations
  Neurofibromatosis Type 2-Yes-Associated Protein and Transcriptional Coactivator With PDZ-Binding Motif Dual Immunohistochemistry Is a Reliable Marker for the Detection...
  Yan Li, Soo-Ryum Yang, Ying-Bei Chen, Prasad S Adusumilli, Ann Bialik, Francis M Bodd, Marc Ladanyi, Jessica Lopardo, Michael D Offin, Valerie W Rusch, William D Travi...> ;Modern Pathology. 2023 Mar 1
• 5 citations
  Analysis of Tumor Mutational Burden, Progression-Free Survival, and Local-Regional Control in Patents with Locally Advanced Non-Small Cell Lung Cancer Treated With Che...
  Emily S Lebow, Annemarie Shepherd, Jordan E Eichholz, Michael Offin, Daphna Y Gelblum, Abraham J Wu, Charles B Simone 2nd, Adam J Schoenfeld, David R Jones, Andreas Ri...> ;JAMA Network Open. 2023 Jan 3
• 2 citations
  A Phase 1 Safety Study of Avelumab Plus Stereotactic Body Radiation Therapy in Malignant Pleural Mesothelioma.
  Andreas Rimner, Prasad S Adusumilli, Michael D Offin, Stephen B Solomon, Etay Ziv, Sara A Hayes, Michelle S Ginsberg, Jennifer L Sauter, Daphna Y Gelblum, Annemarie F ...> ;JTO Clinical and Research Reports. 2023 Jan 1
• Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library.
  Michael Offin, Jennifer L Sauter, Sam E Tischfield, Jacklynn V Egger, Shweta Chavan, Nisargbhai S Shah, Parvathy Manoj, Katia Ventura, Viola Allaj, Elisa de Stanchina,...> ;Genome Medicine. 2022 Nov 15
• 39 citations
  Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer.
  Justin Jee, Emily S Lebow, Randy Yeh, Jeeban P Das, Azadeh Namakydoust, Paul K Paik, Jamie E Chaft, Gowtham Jayakumaran, A Rose Brannon, Ryma Benayed, Ahmet Zehir, Mar...> ;Nature Medicine. 2022 Nov 1
• 6 citations
  Multimodality Therapy in Patients With Primary Pericardial Mesothelioma.
  Michael Offin, Dilanka L De Silva, Jennifer L Sauter, Jacklynn V Egger, Ellen Yorke, Prasad S Adusumilli, Andreas Rimner, Valerie W Rusch, Marjorie G Zauderer> ;Journal of Thoracic Oncology. 2022 Dec 1
• 1 citations
  Tumor volume as a predictor of cell free DNA mutation detection in advanced non-small cell lung cancer.
  Justin M Haseltine, Michael Offin, Jessica R Flynn, Zhigang Zhang, Emily S Lebow, Khaled Aziz, Alex Makhnin, Jordan Eichholz, Lee P Lim, Mark Li, James M Isbell, Danie...> ;Translational Lung Cancer Research. 2022 Aug 1
• 11 citations
  Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset.
  Christopher A Febres-Aldana, Jason C Chang, Ryan Ptashkin, Yuhan Wang, Erika Gedvilaite, Marina K Baine, William D Travis, Katia Ventura, Francis Bodd, Helena A Yu, Al...> ;Clinical Cancer Research. 2022 Nov 1
• 1 citations
  Evolving Landscape of Initial Treatments for Patients with Malignant Pleural Mesotheliomas: Clinical Trials to Clinical Practice.
  Michael Offin, Valerie W Rusch, Andreas Rimner, Prasad S Adusumilli, Marjorie G Zauderer> ;The Oncologist. 2022 Aug 5
• 12 citations
  Clinical Utility and Performance of an Ultrarapid Multiplex RNA-Based Assay for Detection of ALK, ROS1, RET, and NTRK1/2/3 Rearrangements and MET Exon 14 Skipping Alte...
  Ying-Hsia Chu, Jada Barbee, Soo-Ryum Yang, Jason C Chang, Priscilla Liang, Kerry Mullaney, Roger Chan, Paulo Salazar, Ryma Benayed, Michael Offin, Alexander Drilon, Ma...> ;The Journal of Molecular Diagnostics. 2022 Jun 1
• 7 citations
  Effects of Tumor Mutational Burden and Gene Alterations Associated with Radiation Response on Outcomes of Postoperative Radiation Therapy in Non-Small Cell Lung Cancer.
  Narek Shaverdian, Annemarie F Shepherd, Xingzhe Li, Michael Offin, Harry B Lengel, Daphna Y Gelblum, Abraham J Wu, Charles B Simone 2nd, Andreas Rimner, David R Jones,...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Jun 1
• ARCS-M: forging progress from this negative trial in malignant pleural mesothelioma.
  Marjorie G Zauderer, Michael Offin> ;The Lancet. Oncology. 2022 Apr 1
• 8 citations
  Immune biomarkers and response to checkpoint inhibition of BRAFand BRAF non-V600 altered lung cancers.
  Yonina R Murciano-Goroff, Terry Pak, Sebastian Mondaca, Jessica R Flynn, Joseph Montecalvo, Natasha Rekhtman, Darragh Halpenny, Andrew J Plodkowski, Stephanie L Wu, Ma...> ;British Journal of Cancer. 2022 Apr 1
• 9 citations
  Pre-treatment immune status predicts disease control in NSCLCs treated with chemoradiation and durvalumab.
  Maria Thor, Annemarie F Shepherd, Isabel Preeshagul, Michael Offin, Daphna Y Gelblum, Abraham J Wu, Aditya Apte, Charles B Simone 2nd, Matthew D Hellmann, Andreas Rimn...> ;Radiotherapy and Oncology. 2022 Feb 1
• 12 citations
  Image-guided interventional radiological delivery of chimeric antigen receptor (CAR) T cells for pleural malignancies in a phase I/II clinical trial.
  Mario Ghosn, Waseem Cheema, Amy Zhu, Jennifer Livschitz, Majid Maybody, Franz E Boas, Ernesto Santos, DaeHee Kim, Jason A Beattie, Michael Offin, Valerie W Rusch, Marj...> ;Lung Cancer. 2022 Mar 1
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Journal Articles

• PD-L1 Expression, Tumor Mutational Burden, and Response to Immunotherapy in Patients with MET Exon 14 Altered Lung Cancers  
  G J Riely, J Dienstag, C Mrad, J K Sabari, M G Kris, K C Arbour, D F Halpenny, N Rekhtman, R Chen, A J Plodkowski, P K Paik, B T Li, I Bergagnini, M D Offin, C M Rudin..., Annals of Oncology

Lectures

• Efficacy of ramucirumab and docetaxel given either before or after immune checkpoint inhibitors in patients with lung cancers. 
  2019 ASCO Annual Meeting - 6/1/2019