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9860 Mesa Rim RoadSan Diego, CA 92121
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Summary
- Dr. Michael Rafii is Professor of Neurology at Keck School of Medicine of the University of Southern California. He completed his medical education at The Warren Alpert Medical School of Brown University, followed by an internship and residency in neurology at Johns Hopkins University. His research primarily focuses on Alzheimer's disease and Down syndrome, with several publications in high-impact journals. He has led multiple clinical trials related to these conditions. He is author of First Aid for the Neurology Boards and First Aid for the Neurology Clerkship.
Education & Training
Johns Hopkins UniversityResidency, Neurology, 2003 - 2006- Johns Hopkins UniversityInternship, Internal Medicine, 2002 - 2003
The Warren Alpert Medical School of Brown UniversityClass of 2002
Certifications & Licensure
CA State Medical License 2006 - 2028
American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2015-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory EHR Suite, Epic Systems Corporation, 2015-2017
Clinical Trials
Publications & Presentations
PubMed
- Delayed Recognition and Stroke-Predominant Presentation in Down Syndrome-Associated Moyamoya Syndrome.Jonathan D Santoro, Mackenzie Silverman, Anthony C Wang, Deepti Nagesh, Eugenia Ho
Stroke. 2026-09-01 - Correction: Serum and cerebral folate are normal in Down Syndrome Regression Disorder.Jonathan D Santoro, Mackenzie Silverman, Lilia Kazerooni, Samuel T Otey, Maeve C Lucas
Molecular Autism. 2026-07-30 - Relationships between longitudinal retinal amyloid imaging and amyloid PET in the A4 Trial.Sonal Sukreet, Michael C Donohue, Jennifer Ngolab, Alison Belsha, Jennifer Salazar
Alzheimer's & Dementia. 2026-07-08
Journal Articles
- Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer DiseaseReisa Sperling, Michael S Rafii, JAMA Neurology
Press Mentions
Alzheimer's Meds Are Here. But for the down Syndrome Community, It's Still the 1980sMarch 1st, 2023- Top Dementia Scientists Present Key Findings, InitiativesNovember 28th, 2022
- It’s Not a Normal Sign of Aging: Mild Cognitive Impairment Takes TollApril 19th, 2022
Grant Support
- Life’s end Benefits of CannaBidiol and TetrahYdrocannabinol (LiBBY) Open-Label Extension (OLE) StudyMEDICAL UNIVERSITY OF SOUTH CAROLINA2025–2028
- Precision Medicine for Inflammatory Treatment for Alzheimer's Disease in Down SyndromeUNIVERSITY OF SOUTHERN CALIFORNIA2021–2026
- Clinical trials to prevent Alzheimer's Disease in Down SyndromeUNIVERSITY OF SOUTHERN CALIFORNIA2019–2025
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